ABSTRACT
PURPOSE OF INVESTIGATION: To propose a multidisciplinary protocol for postmortem disclosure of complex fetal malformations, comparing ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and autopsy in a case of conjoined ischiopagus twins. MATERIALS AND METHODS: A screening second-trimester ultrasound diagnosed ischiopagus twins at 20 gestational weeks in a 31-year-old woman without any previous ultrasound examination. The couple decided for pregnancy termination. The formalin-fixed fetuses underwent full-body CT, MRI, and autopsy. RESULTS: ultrasound accurately diagnosed ischiopagus twins. CT was very accurate in the description of bone components. MRI allowed better visualization of the visceral organs than CT. Only autopsy could disclose the aspect of the two gastrointestinal tracts and the external genitalia. CONCLUSIONS: Prenatal ultrasound represents the standard diagnostic exam for conjoined twins. CT-MRI virtual autopsy (virtopsy) may be an option if the couple refuses to authorize necropsy or may be useful to plan a minimally invasive autopsy preserving the external phenotype.
Subject(s)
Twins, Conjoined/pathology , Adult , Autopsy/methods , Female , Humans , Magnetic Resonance Imaging/methods , Pregnancy , Pregnancy Reduction, Multifetal/methods , Pregnancy Trimester, Second , Tomography, X-Ray Computed/methods , Ultrasonography, Prenatal/methodsSubject(s)
Attitude to Health , Decision Making , Down Syndrome/diagnosis , Mothers/psychology , Prenatal Diagnosis/psychology , Female , Humans , Male , PregnancyABSTRACT
El artículo hace referencia a casos clínicos de efectos adversos graves en la administración intramuscular de Penicilina Benzatínica, aún bajo observancia de buena técnica de administración. Se destacan además aspectos relevantes del procedimiento de administración de medicamentos por esta vía (AU)
Subject(s)
Humans , Male , Child , Adolescent , Adult , Penicillin G Benzathine/adverse effects , Injections, Intramuscular/adverse effects , Injections, Intramuscular/standards , Injections, Intra-Arterial/adverse effectsABSTRACT
El artículo hace referencia a casos clínicos de efectos adversos graves en la administración intramuscular de Penicilina Benzatínica, aún bajo observancia de buena técnica de administración. Se destacan además aspectos relevantes del procedimiento de administración de medicamentos por esta vía
