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6.
Cutis ; 41(5): 347-50, 1988 May.
Article in English | MEDLINE | ID: mdl-2836133

ABSTRACT

The clinical picture of neuropathy caused by dapsone is usually progressive muscle weakness and wasting, most often involving distal muscles of the extremities. Two patients with neurologic symptoms following the use of dapsone for dermatitis herpetiformis are reported. Both patients had normal motor conduction velocities, and negative results on physical examination of muscle wasting. We conclude that their clinical presentation was not due to dapsone-induced neuropathy. A discussion and a review of cases of this unusual effect of dapsone are included.


Subject(s)
Dapsone/adverse effects , Dermatitis Herpetiformis/drug therapy , Peripheral Nervous System Diseases/chemically induced , Adult , Dermatitis Herpetiformis/pathology , Electromyography , Humans , Male , Neural Conduction , Peripheral Nervous System Diseases/diagnosis , Skin/pathology
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