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Trends Parasitol
; 39(8): 622-625, 2023 08.
Article
in English
| MEDLINE
| ID: mdl-37302957
ABSTRACT
Protein disulfide isomerases (PDIs) ensure that specific substrate proteins are correctly folded. PDI activity plays an essential role in malaria transmission. Here we provide an overview of the role of PDIs in malaria-causing Plasmodium parasites and outline why PDI inhibition could be a novel way to treat malaria and prevent transmission.