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2.
Fitoterapia ; 73(4): 346-50, 2002 Jul.
Article in English | MEDLINE | ID: mdl-12234582

ABSTRACT

Methanol extracts of 36 medicinal plants from La Réunion Island were evaluated against two viruses: Herpes simplex type 1 (HSV-1) and poliovirus type 2 (PV). Five of them showed an effect against HSV-1 and five against PV, Senecio ambavilla being inhibitor for both viruses.


Subject(s)
Antiviral Agents/pharmacology , Herpesvirus 1, Human/drug effects , Phytotherapy , Plant Extracts/pharmacology , Plants, Medicinal , Poliovirus/drug effects , Humans , Microbial Sensitivity Tests , Plant Leaves , Plant Stems , Reunion
3.
Chem Pharm Bull (Tokyo) ; 49(5): 619-21, 2001 May.
Article in English | MEDLINE | ID: mdl-11383617

ABSTRACT

A new coumarin identified as 5-hydroxy-6-methoxy-7-(3-methyl-but-2-enyloxy)-2H-1-benzopyran-2-one (isoobtusitin) was isolated from Psiadia dentata. This compound showed, in vitro, a moderate inhibitory activity against poliovirus and a very weak activity against (HIV), whereas it was inactive against (HSV1), (VSV), and murine tumoral cell lines (3LL, L1210).


Subject(s)
Coumarins/isolation & purification , Coumarins/pharmacology , Plants, Medicinal/chemistry , Animals , Anti-HIV Agents/pharmacology , Antineoplastic Agents, Phytogenic/isolation & purification , Antineoplastic Agents, Phytogenic/pharmacology , Antiviral Agents/isolation & purification , Antiviral Agents/pharmacology , Magnetic Resonance Spectroscopy , Mass Spectrometry , Mice , Plant Leaves/chemistry , Poliovirus/drug effects , Reunion , Spectrophotometry, Infrared , Spectrophotometry, Ultraviolet , Tumor Cells, Cultured
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