ABSTRACT
Nine patients with choledocholithiasis or cholelithiasis developed transient elevations of serum glutamic oxalacetic transaminase (SGOT) levels of greater than 600 units. Awareness of such transient biliary disease will prevent an unnecessary evaluation of a primary hepatocellular disorder. In our study, we concluded that 1) The SGOT level rose and fell rapidly within a 24- to 72-hour period. 2) Higher SGOT levels were seen in patients with choledocholithiasis in whom the gallbladder had been removed. 3) In patients with choledocholithiasis a fall in SGOT level did not necessarily mean the stone had passed.
Subject(s)
Aspartate Aminotransferases/blood , Cholelithiasis/enzymology , Gallstones/enzymology , Adult , Aged , Female , Humans , MaleABSTRACT
Twenty-two patients with multiple relapses of antibiotic-associated pseudomembranous colitis underwent a tapering dose of oral vancomycin for 21 days and a pulse dose of vancomycin for 21 days. In follow-up ranging from 2-12 months with a mean of 6 months, all patients have been without recurrence of the antibiotic-associated pseudomembranous colitis.
Subject(s)
Enterocolitis, Pseudomembranous/drug therapy , Vancomycin/administration & dosage , Administration, Oral , Adult , Aged , Anti-Bacterial Agents/administration & dosage , Clostridium/physiology , Drug Administration Schedule , Drug Therapy, Combination , Humans , Middle Aged , Recurrence , Spores, Bacterial/drug effectsSubject(s)
Colitis/chemically induced , Anti-Bacterial Agents/adverse effects , Anti-Inflammatory Agents/adverse effects , Antineoplastic Agents/adverse effects , Cimetidine/adverse effects , Contrast Media/adverse effects , Enema/adverse effects , Enterocolitis, Pseudomembranous/chemically induced , Ergot Alkaloids/adverse effects , Estrogens/adverse effects , Ethanol/adverse effects , Flucytosine/adverse effects , Gold/adverse effects , Humans , Methyldopa/adverse effects , Penicillamine/adverse effects , Progesterone/adverse effects , Soaps/adverse effects , Vasopressins/adverse effectsABSTRACT
A patient with hyperviscosity syndrome was noted to have an abnormal liver radionuclide scan. Ultrasound and normalization of the liver scan after plasmapheresis confirmed the non-neoplastic nature of the patchy labeling defects. This case suggests a new cause for labeling abnormalities on liver radionuclide scans in patients with a syndrome where liver biopsies would be unusually hazardous. Possible mechanisms for this scintigraphic pattern in the hyperviscosity syndrome are briefly discussed.
