ABSTRACT
In 1967, Watson described children in three families with pulmonary valve stenosis, dull intelligence, short stature, and cafe-au-lait spots. We present the case of an undiagnosed adult with coronary artery disease, the Watson syndrome characteristics, and a pulmonary artery aneurysm secondary to pulmonic stenosis.
Subject(s)
Aneurysm/surgery , Coronary Artery Disease/surgery , Neurofibromatosis 1/surgery , Pulmonary Artery , Pulmonary Valve Stenosis/surgery , Cafe-au-Lait Spots/etiology , Humans , Male , Middle AgedABSTRACT
PURPOSE: We report a case of small-cell undifferentiated carcinoma with neuroendocrine (SCUCN) of the gallbladder in a 67-year-old man who presented with suspected cholelithiasis. Treatment included a cholecystectomy and a 4-cycle course of etoposide and carboplatin. CONCLUSIONS: Small-cell undifferentiated carcinoma with neuroendocrine features of the gallbladder is a rare disease with approximately 30 cases reported in the literature. Clinical characteristics include an association with cholelithiasis, an elderly age distribution, a female preponderance, and a correlation with cigarette smoking. It is known to behave aggressively and carry a grave prognosis, with extensive local invasion and early metastasis being characteristic. Medical and surgical therapies exist and have demonstrated best results when used in combination.
ABSTRACT
This paper presents standard and innovative retrofit details which have been used by Caltrans to retrofit existing highway bridge and also discusses some innovative seismic details currently being used for new construction of highway bridges resulting from lessons learned from the San Fernando )1971), Loma Prieta (1989), Northridge (1994) and Kobe (1995) earthquakes. (AU)
