Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 22
Filter
1.
Tech Coloproctol ; 25(9): 1045-1054, 2021 09.
Article in English | MEDLINE | ID: mdl-34110535

ABSTRACT

BACKGROUND: Minimally invasive techniques for treating pilonidal disease are safe and effective alternatives to conventional surgery, with improved recovery time, cosmetic results, and pain control. The aim of this study was to evaluate the 5-year surgical outcomes of a single-center case series treated with endoscopic pilonidal sinus treatment (EPSiT). METHODS: We conducted a retrospective single-center analysis of all patients treated with EPSiT, by a single surgical team, from March 2015 to December 2019, for primary or recurrent pilonidal disease. The primary outcomes were recurrence, persistence and treatment failure. The secondary outcomes were postoperative pain, painkiller use, time off work, satisfaction, complications, wound healing time, time to persistence or recurrence. RESULTS: Forty-two patients underwent 46 EPSiT procedures [34 males, 8 females, median age 25 (IQR 13.75) years] for primary (47.8%) or recurrent pilonidal disease (52.2%). All patients completed the follow-up [median 62 (IQR 43) months]. The single procedure healing rate was 76.1%. The healing rate for the first procedures plus the second EPSiT procedure (performed in 4 cases) was 83.3%. Among the 46 EPSiT procedures, we recorded six cases of persistence (13.0%) and five cases of recurrence (10.9%) The median operative time was 32.5 (IQR 18.75) minutes, the median pain score (visual analog scale) in week 1 was 2 (IQR 2), and the median time off work was 4 (IQR 2) days. Four patients (8.7%) experienced complications: serosanguineous (n = 2) or seropurulent discharge (n = 2). The satisfaction rate was 95.7%. CONCLUSIONS: In our experience, EPSiT is safe, well accepted. and associated with a low level of postoperative pain, short hospitalization, short time off work, as well as optimal cosmetic results. Its failure rate is similar to that of excisional surgery.


Subject(s)
Pilonidal Sinus , Adult , Female , Humans , Male , Neoplasm Recurrence, Local , Pain, Postoperative/etiology , Pilonidal Sinus/surgery , Recurrence , Retrospective Studies , Treatment Outcome
2.
Minerva Urol Nefrol ; 54(2): 131-3, 2002 Jun.
Article in English | MEDLINE | ID: mdl-12070462

ABSTRACT

Retroperitoneal lipomas are a heterogeneous group of mesenchymal tumors. They are usually large and occur most frequently in the retroperitoneal, perineal and pelvic regions. Lipomas grow slowly surrounding the retroperitoneal and pelvic organs, with a displacement of bowel and vascular axis. A case of a 61-year-old male patient which referred urinary frequency, urgency and nocturia is presented. Urodynamics evidenced a detrusor instability in a low capacity bladder. CT scan demonstrated a bladder dome compression due to a huge retroperitoneal mass extending from the right hepatic lobe to the hypogastric region and the right thigh. Surgical complete resection was performed: histology demonstrated a lipoma with areas of well differentiated myxoid degeneration. After surgery the irritative urinary symptoms disappeared. This is the first case described in literature of detrusor instability due to bladder compression by retroperitoneal lipoma.


Subject(s)
Lipoma/complications , Retroperitoneal Neoplasms/complications , Urinary Incontinence/etiology , Gait Disorders, Neurologic/etiology , Humans , Lipoma/diagnostic imaging , Lipoma/surgery , Male , Middle Aged , Retroperitoneal Neoplasms/diagnostic imaging , Retroperitoneal Neoplasms/surgery , Ultrasonography , Urodynamics
3.
Chir Ital ; 53(3): 399-404, 2001.
Article in English | MEDLINE | ID: mdl-11452827

ABSTRACT

The small cell carcinoma is a neuroendocrine tumour characterised by an aggressive clinical course and a high mortality rate. It occurs most commonly in the lung. Small cell carcinomas originating in the genitourinary system have been diagnosed with increasing frequency in recent years, because of the use of immunohistochemistry. Prostatic small cell carcinomas present the same biological behavior and similar histological, immunohistochemical and ultrastructural features to small cell carcinomas of the lungs. We describe the clinico-pathological findings in a 65-year-old male patient with a diagnosis of prostatic small cell carcinoma, obtained by means of a tru-cut needle biopsy. We performed the immunohistochemical tests using neuron-specific enolase and chromogranin A antibodies, according to the literature. On the basis of our experience we stress the malignant features of small cell carcinoma and the difficulty in obtaining an early diagnosis and treatment because of the aggressive course of the lesion and the late symptomatology.


Subject(s)
Carcinoma, Small Cell/pathology , Prostatic Neoplasms/pathology , Aged , Biopsy, Needle/methods , Humans , Male
4.
Chir Ital ; 53(3): 425-9, 2001.
Article in Italian | MEDLINE | ID: mdl-11452832

ABSTRACT

The Authors present a case of inflammatory pseudotumour (IPT) of the urinary bladder occurring in a 57-year-old female patient, who was referred to our department with haematuria, stranguria and hypogastric pain. Ultrasonographic, radiological and endoscopic examinations showed a sessile, ulcerated, easily bleeding bladder formation; urinary cytology revealed no atypical transitional cells. Abdomino-pelvic computed tomography analysis showed thickening of the bladder walls and infiltration of the perivesical fat. Histopathologically, the formation was indicated as an inflammatory pseudotumour (IPT) of the bladder. The patient underwent TURB (transurethral resection of the bladder) and was discharged clinically healed on postoperative day 4. A one-year follow up revealed no evidence of recurrence. On the basis of their experience and a thorough review of the literature review, the Authors discuss the clinico-pathological features of IPT of the bladder and the possible factors involved in the malignant transformation of IPT. In conclusion, the benign nature of the lesion is stressed.


Subject(s)
Granuloma, Plasma Cell , Urinary Bladder Diseases , Female , Granuloma, Plasma Cell/diagnosis , Granuloma, Plasma Cell/etiology , Humans , Middle Aged , Urinary Bladder Diseases/diagnosis , Urinary Bladder Diseases/etiology
5.
Surg Radiol Anat ; 23(6): 427-31, 2001.
Article in English | MEDLINE | ID: mdl-11963626

ABSTRACT

Left testicular vein anatomy has received more attention due to the presence of competent or incompetent venous valves and bypassing anastomoses, which are involved in venographic diagnosis and embolisation of varicocele. The left gonadal vein develops, in both males and females, between the 5th and 7th intrauterine weeks, being derived from the distal or postrenal portion of the left subcardinal vein. The varicocele aetiologic hypothesis leads to ontogenetic disturbances in the development of the secondary venous system. Retrograde testicular venography shows the precise anatomy of the left pampiniform plexus, while anterograde testicular venography identifies the presence of the valve and possible continence. In the present case sclerotherapy could not be achieved due to testicular vein anomalies. Sclerotherapy versus surgical high ligature of the left testicular vein in cases of left idiopathic varicocele with testicular vein anomalies is discussed.


Subject(s)
Sclerotherapy , Testis/blood supply , Varicocele/pathology , Varicocele/therapy , Adult , Humans , Male , Phlebography , Treatment Failure , Varicocele/diagnostic imaging , Veins/abnormalities
6.
Chir Ital ; 52(2): 147-53, 2000.
Article in Italian | MEDLINE | ID: mdl-10832540

ABSTRACT

The need to discover malignancy is the most challenging dilemma in the management of thyroid nodules, the most common endocrine disorders, affecting 4-5% of the general population. Malignancies account for only 2-3% of cases. The aim of our study was to evaluate the predictive value of preoperative fine-needle aspiration cytology (FNAC) in surgical decision making by evaluating the final pathologic diagnosis and comparing it to the preoperative and intraoperative diagnoses. We conducted a prospective study of 30 thyroid resections. The mean age was 49 years (range: 27 to 68 years). Preoperative physical and laboratory examinations, presenting symptoms, imaging studies and predictive values of preoperative and intraoperative FNAC were analyzed. The consistency of the lesion was strongly predictive of malignancy, when "hard". Single lesions were also predictive of malignancy. The diagnostic accuracy of preoperative FNAC vs intraoperative FNAC vs frozen section histopathology was 90% vs 100% vs 96.7%; sensitivity: 91.6% vs 100% vs 100%; specificity: 90.5% vs 100% vs 94.7%, while the positive predictive value was 84.6% vs 100% vs 91.7%, and the negative predictive value 95% vs 100% vs 100%. Ultrasound-guided preoperative FNAC showed high specificity, sensitivity and accuracy in diagnosing malignancy in thyroid nodules. Intraoperative FNAC was more accurate than intraoperative frozen sections in diagnosing malignancy in thyroid nodules.


Subject(s)
Biopsy, Needle , Thyroid Gland/pathology , Thyroid Nodule/pathology , Adult , Aged , Biopsy, Needle/methods , Diagnosis, Differential , Female , Frozen Sections , Humans , Intraoperative Care , Male , Middle Aged , Preoperative Care , Sensitivity and Specificity , Thyroid Nodule/diagnosis , Thyroid Nodule/surgery
7.
Chir Ital ; 52(6): 707-11, 2000.
Article in Italian | MEDLINE | ID: mdl-11200008

ABSTRACT

Three cases of urothelial inverted papilloma, detected in two female patients aged 32 and 31 years, respectively and in one 67-year-old male patient, are described. Inverted papilloma is a benign lesion which occurs in the urinary epithelium with a 20% incidence in comparison with other urothelial tumours. The male:female ratio is 3:1. The histological structure of urothelial inverted papilloma is similar to that of inverted papilloma of the nasal and paranasal sinuses. It presents interanastomosed epithelial cords, with transitional cells, which develop in the tunica propria connective tissue. Some cells are distributed in such a way as to constitute vacuolated glandular-like structures. The histogenetic origin of the lesion from Home subtrigonal or Albarran subcervical glands is debatable. Recent aetiological hypotheses have claimed that the origin of the lesion may be related to Brunn's nest hyperplasia and/or to chronic urothelial inflammation. The latter hypothesis would currently appear to be the most accredited: immunostaining for cytokeratins would tend to support a urothelial inflammatory aetiology. In our cases, we achieved a definitive diagnosis of inverted papilloma only at histology, because of the specificity of the echotomography and cystoscopy findings. Urinary cytology revealed only a large number of inflammatory cells with anaplastic elements, but without any more detailed morphological description. We performed a transurethral resection of the bladder (TURB) in all three patients: routine follow-up showed the absence of inverted papilloma relapses. On the basis of the above-mentioned data and a thorough review of the literature, we attempt to assess and classify the clinico-pathological findings and the aetiological hypotheses of urothelial inverted papilloma. In addition, the benign nature of the lesion and any malignant transformation factors are discussed.


Subject(s)
Kidney Neoplasms/pathology , Papilloma, Inverted/pathology , Urinary Bladder Neoplasms/pathology , Adenocarcinoma/pathology , Adult , Aged , Female , Humans , Male
8.
G Chir ; 20(1-2): 47-50, 1999.
Article in English | MEDLINE | ID: mdl-10097456

ABSTRACT

The Authors describe the interposition vein cuff technique as an adjuvant method to infrainguinal prosthetic bypass grafts. The haemodynamic, mechanical and humoral factors thought to be involved in the beneficial effects of the vein cuff are herein discussed. The results of the main series suggest the use of this method particularly in patients without any available autologous vein conduit requiring a below-knee popliteal or crural reconstruction.


Subject(s)
Blood Vessel Prosthesis , Ischemia/surgery , Leg/blood supply , Veins/transplantation , Anastomosis, Surgical , Arteries/surgery , Follow-Up Studies , Humans , Hyperplasia , Polytetrafluoroethylene , Prosthesis Design , Time Factors , Tunica Intima/pathology , Vascular Patency
9.
Minerva Med ; 87(1-2): 53-5, 1996.
Article in Italian | MEDLINE | ID: mdl-8610026

ABSTRACT

Ten patients affected with HCV-related chronic hepatitis received alpha lymphoblastoid-IFN, 3 mU i.m. TW, for 12 months. We obtained: 4 complete responses, 5 partial responses, 1 non-response (therapy stopped after 3 months). During the fourteen months follow-up, 4 patients (1 complete responder, 3 partial responders) relapsed.


Subject(s)
Hepatitis C/therapy , Interferon-alpha/administration & dosage , Adult , Chronic Disease , Drug Evaluation , Female , Follow-Up Studies , Humans , Male , Middle Aged , Remission Induction , Time Factors
10.
Minerva Med ; 81(9): 641-4, 1990 Sep.
Article in Italian | MEDLINE | ID: mdl-2234488

ABSTRACT

A case of central nervous system toxoplasmosis is reported. Attention is called to the diagnosis of this infection; moreover, the authors emphasize the importance of the TAC brain for the diagnosis and evaluation of the clinical evolution and response to the therapy.


Subject(s)
Brain Diseases/diagnostic imaging , Tomography, X-Ray Computed , Toxoplasmosis/diagnostic imaging , Adult , Brain Diseases/diagnosis , Brain Diseases/parasitology , Female , Humans , Toxoplasmosis/diagnosis
11.
Minerva Med ; 81(6): 495-7, 1990 Jun.
Article in Italian | MEDLINE | ID: mdl-2359505

ABSTRACT

The Authors report a case of leptospirosis. Stress is laid on the sporadicity of this infection in their region; attention is also drawn to the variety of the clinical expression of this disease.


Subject(s)
Leptospirosis/diagnosis , Adult , Humans , Italy/epidemiology , Leptospirosis/epidemiology , Male
12.
Radiol Med ; 79(5): 453-7, 1990 May.
Article in Italian | MEDLINE | ID: mdl-2359852

ABSTRACT

Liver regeneration after partial hepatectomy was studied in rats by means of magnetic resonance (MR) imaging and T1 relaxation time. Fourteen hepatectomized rats were compared to sham operated ones and to controls which had not undergone any surgical treatment. The animals were imaged at 0.5 T, and inversion recovery (IR) technique was employed at the T-null of liver before surgery. T1 was determined in vitro with spectroscopy. Regenerating rat liver exhibited a significantly high increase in MR signal intensity and T1 values (p less than 0.05) 24 hours after surgery, returning to baseline values at 2 weeks. Sham operated animals and controls did not exhibit significant changes in signal intensity from baseline values (p greater than 0.05). These findings suggest that MR imaging is able to detect the pathophysiological changes occurring in liver parenchyma during the regenerating process and to monitor different stages of the hyperplastic process.


Subject(s)
Disease Models, Animal , Liver Regeneration , Liver/pathology , Magnetic Resonance Imaging , Animals , Hepatectomy , Laparotomy , Liver/analysis , Magnetic Resonance Imaging/instrumentation , Magnetic Resonance Imaging/methods , Magnetic Resonance Spectroscopy/instrumentation , Magnetic Resonance Spectroscopy/methods , Rats , Rats, Inbred Strains
13.
Minerva Med ; 81(3): 157-68, 1990 Mar.
Article in Italian | MEDLINE | ID: mdl-2108397

ABSTRACT

Non-A, non-B hepatitis (NANB) is, after type B hepatitis, the most frequently encountered form of hepatitis. Parenteral transmission and apparently nonparenteral or "sporadic" forms are described. The epidemiology of this new form of hepatitis is examined in the light of personal experience and of reported data.


Subject(s)
Hepatitis C/epidemiology , Hepatitis, Viral, Human/epidemiology , Disease Outbreaks , Global Health , Hepatitis C/diagnosis , Hepatitis C/transmission , Humans , Italy/epidemiology , Risk Factors , Substance-Related Disorders/complications , Substance-Related Disorders/epidemiology
14.
Minerva Med ; 81(3): 169-73, 1990 Mar.
Article in Italian | MEDLINE | ID: mdl-2108398

ABSTRACT

Personal experience with a series of 69 cases of non-A, non-B viral hepatitis out of 164 cases of acute viral hepatitis observed at hospital admission between January 1985 and June 1988 is reported. Agreement is expressed with other Italian series as regards the incidence of sex, of the most involved age classes, of the most affected professional categories and of the incubation period of posttransfusional forms. The prevalence of sporadic forms over those transmitted intraparenterally and more prolonged course in icterus patients and in parenteral forms is pointed out.


Subject(s)
Hepatitis C/epidemiology , Hepatitis, Viral, Human/epidemiology , Acute Disease , Age Factors , Hepatitis C/diagnosis , Hepatitis C/transmission , Humans , Incidence , Italy/epidemiology , Sex Factors
15.
Minerva Med ; 81(1-2): 107-9, 1990.
Article in Italian | MEDLINE | ID: mdl-2314612

ABSTRACT

A case of induced pemphigus occurring in a patient affected with a brucellosis is reported with emphasis on the definitive remission of the pemphigus after antibiotic therapy against brucellosis and in the absence of corticosteroid treatment. Attention is also drawn to a possible autoimmune mechanism of the pemphigus triggered by brucellosis.


Subject(s)
Brucellosis/complications , Pemphigus/etiology , Anti-Bacterial Agents/therapeutic use , Brucellosis/drug therapy , Brucellosis/immunology , Complement C3/analysis , Humans , Immunoglobulin G/analysis , Male , Middle Aged , Pemphigus/immunology
16.
Ital J Neurol Sci ; 10(2): 211-3, 1989 Apr.
Article in English | MEDLINE | ID: mdl-2737869

ABSTRACT

A 36 year old woman with anterior sacral meningocele developed a purulent meningitis secondary to the rupture of the meningeal sac into the rectum. The value of neuroradialogical studies, especially CT, is emphasized.


Subject(s)
Meningitis/etiology , Meningocele/complications , Adult , Female , Humans , Meningocele/diagnostic imaging , Rectum , Rupture, Spontaneous , Tomography, X-Ray Computed
17.
Minerva Med ; 80(3): 303-4, 1989 Mar.
Article in Italian | MEDLINE | ID: mdl-2717051

ABSTRACT

A case of visceral leishmaniasis in a female patient suffering from acute nonlymphoid leukaemia is reported. Stress is laid on the atypical nature of the clinical picture, falsified by the underlying disease, and attention is called to the behaviour of Leishmania as an opportunistic agent in the immunodepressed host.


Subject(s)
Leishmaniasis, Visceral/complications , Leukemia, Myeloid, Acute/complications , Opportunistic Infections/complications , Female , Humans , Leishmaniasis, Visceral/diagnosis , Leishmaniasis, Visceral/drug therapy , Leishmaniasis, Visceral/pathology , Leukemia, Myeloid, Acute/pathology , Meglumine/administration & dosage , Middle Aged , Opportunistic Infections/diagnosis , Opportunistic Infections/drug therapy , Opportunistic Infections/pathology , Time Factors
18.
Minerva Med ; 79(6): 427-34, 1988 Jun.
Article in Italian | MEDLINE | ID: mdl-2454420

ABSTRACT

In the light of the international literature and personal observation, the diagnostic techniques employed in Pneumocystis Carinii Pneumonia (PCP), a major opportunistic infection of acquired immunodeficiency syndrome (AIDS) are reviewed.


Subject(s)
Pneumonia, Pneumocystis/diagnosis , Acquired Immunodeficiency Syndrome/complications , Animals , Humans , Immunologic Tests , Pneumocystis/isolation & purification , Pneumonia, Pneumocystis/diagnostic imaging , Pneumonia, Pneumocystis/immunology , Radiography , Staining and Labeling
19.
Minerva Med ; 74(27): 1635-8, 1983 Jun 30.
Article in Italian | MEDLINE | ID: mdl-6856173

ABSTRACT

The behaviour of serum immunoglobulins in 35 patients suffering from Mediterranean exanthematous has been studied. No particular quantitative or qualitative change lieve noted. Supported by the scanty and contrasting data in existing literature, it is maintained that aspecific immunological serum doses are of little use, but research is urged into specific antibodies by means of indirect immunofluorescence and the Elisa method.


Subject(s)
Boutonneuse Fever/immunology , Immunoglobulins/analysis , Rickettsiaceae Infections/immunology , Adult , Aged , Humans , Immunoglobulin A/analysis , Immunoglobulin G/analysis , Immunoglobulin M/analysis , Middle Aged
20.
Arch Sci Med (Torino) ; 139(4): 435-40, 1982.
Article in Italian | MEDLINE | ID: mdl-6820268

ABSTRACT

The importance of perinatal infection in the mother-foetus transmission of HbsAg positive hepatitis is stressed. The role of type A hepatitis has no influence and that of the NANB is little known. The Authors maintain that in no case is the hepatitis virus a valid motive for the interruption of pregnancy, even when it occurs in the first months of gestation.


Subject(s)
Hepatitis A/immunology , Hepatitis C/immunology , Hepatitis, Viral, Human/immunology , Pregnancy Complications, Infectious/immunology , Adult , Female , Hepatitis A/transmission , Hepatitis B Surface Antigens/analysis , Hepatitis C/transmission , Humans , Maternal-Fetal Exchange , Pregnancy
SELECTION OF CITATIONS
SEARCH DETAIL
...