[Cardiac manifestations of phospholipid antibody syndrome. Study of 2 cases]. / Les manifestations cardiaques du syndrome des anticorps antiphospholipides. Etude de deux observations.

Cardiac manifestations of phospholipid antibody syndrome may include mitral and/or aortic valve disease, pseudo-infectious endocarditis, thrombi of the right atrium, myocardial infection, pulmonary artery hypertension and cardiomyopathy with global or segmental left ventricular dysfunction. The authors report two patients showing evidence simultaneously of a circulating anticoagulant, dissociated syphilis serology and cardiolipin antibodies at a very high level. They had the majority of cardiac complications described in phospholipid antibody syndrome. Both also had renal involvement and one of them had recurrent venous thromboses and a cerebrovascular accident. Prolonged corticosteroid treatment, combined with anticoagulants in one patient, was accompanied by stability of lesions with follow-up of five years and ten months respectively.

[Deep venous thrombosis of the upper limb complicated by pulmonary embolism. Apropos of a case]. / Thrombose veineuse profonde du membre supérieur compliquée d'embolie pulmonaire. A propos d'un cas.

Venous thrombosis of the upper limb is classically rarely complicated by pulmonary embolism. The authors report a case of phlebitis of the upper limb in a 46-year-old woman with a thoracic outlet syndrome complicated by multiple and recurrent pulmonary emboli. Analysis of recent data from the literature would appear to bring into question the classically accepted harmless nature of this condition regarding the risk of embolic complications.

[Chronic obstructions of the left main and right coronary arteries]. / Occlusions chroniques du tronc coronaire gauche et de la coronaire droite.

The authors report a case of chronic occlusion of the left main coronary associated with occlusion of the second segment of the right coronary artery documented at coronary angiography carried out for effort angina without previous infarction. Myocardial perfusion was preserved mainly by a marginal branch of the right coronary arising immediately before the occluded second segment and by a small branch of the left main coronary artery.

[Cardiotoxicity of 5 fluoro-uracil. Apropos of a case]. / Cardiotoxicité du 5 fluoro-uracile. A propos d'une observation.

The cardiotoxicity of 5 fluoro-uracil is currently recognised. We report here a new case in which an effort test and a Methergin test were carried out in the hours following the episode and at a later date. With normal coronary arteriography the evidence is in favour of coronary artery spasm which is the usual mechanism for this type of toxicity.