ABSTRACT
Chondrodysplasia punctata (CP) is sometimes accompanied by heart lesions, but the literature is not specific or consistent regarding the incidence or types of cardiac anomalies. A patient with the mild Conradi-Hünermann type of CP is peripheral pulmonary arterial stenoses. A review of the literature brought to light a total of 23 patients with congenital heart lesions that were mainly found among cases of Conradi-Hünermann type and autosomal recessively inherited CP.
Subject(s)
Chondrodysplasia Punctata/genetics , Chromosome Aberrations/genetics , Genes, Recessive/genetics , Pulmonary Artery/abnormalities , Angiography , Chondrodysplasia Punctata/diagnosis , Chromosome Disorders , Constriction, Pathologic/genetics , Female , Humans , InfantABSTRACT
Thirty-four cases of tetanus neonatorum seen over a period of 2 years are analysed as regards severity, place and mode of birth of the affected infant and level of antenatal care. Possible methods of prevention are discussed in the light of the findings.
Subject(s)
Infant, Newborn, Diseases/epidemiology , Tetanus/epidemiology , Delivery, Obstetric , Humans , Infant, Newborn , Physical Examination , South Africa , Tetanus/etiologyABSTRACT
A case of neonatal tetanus in an infant with myelomeningocele is described, and the possible action of tetanus toxin is discussed.
Subject(s)
Infant, Newborn, Diseases/etiology , Tetanus/etiology , Humans , Infant, Newborn , Male , Meningomyelocele/complications , Tetanus/pathologyABSTRACT
A case of congenital stippled epiphyses is presented, and attention is drawn to the possibility that this condition was caused by maternal ingestion of warfarin during early pregnancy.
