ABSTRACT
BACKGROUND: Direct coronary stenting is the dominant technique for coronary stent implantation, but previous randomized studies have strongly selected lesions to treat. To evaluate whether the results can be generalized to routine clinical practice, all consecutive patients with direct stenting in 15 hospitals were entered into a prospective registry. Single vessels and simple lesions, but also multivessel, complex and long lesions, and small vessels size (< or =2.5 mm) were included. Immediately results as well as clinical events within 30 days after the procedure were evaluated. METHODS: Between April and November 2002, direct coronary stenting was performed in 452 consecutive patients (559 lesions) at 15 sites. Stents edge-protected by "sleeves" (SOX technology, NIR Stent, Boston Scientific) or with short transitional edge protection (STEP technology, Multilink Stents, Guidant) were selected to minimize vessel injury outside the stent edges during balloon inflation/deployment. RESULTS: Stents were successfully implanted in 96% of lesions. Lesions were multivessel in 27%, type B2-C in 40%, very angulated in 28%, calcified in 18%, and longer than 20 mm in 10% of patients. Vessels were smaller than < or =2.5 mm in 27% of patients. Direct coronary stenting was unsuccessful in 25 lesions (24 patients) characterized by more unstable angina (p=0.07), more treated lesions (p<0.01), and more distal locations (p=0.001). Dissection occurred in 6% of patients, and one stent embolised. The 30-day follow-up period included 1 death (due to subacute occlusion), 11 (2.4%) acute myocardial infarctions (8 non-Q wave), and one stroke (following carotid surgery). CONCLUSIONS: Direct coronary stenting yielded excellent results at 30 days although some expanded indications will be included.
Subject(s)
Coronary Disease/therapy , Stents , Aged , Angioplasty, Balloon, Coronary , Blood Vessel Prosthesis Implantation , Calcinosis/diagnostic imaging , Calcinosis/surgery , Coronary Angiography , Coronary Disease/mortality , Female , Follow-Up Studies , Humans , Male , Middle Aged , Postoperative Complications/etiology , Postoperative Complications/mortality , Prospective Studies , Registries/statistics & numerical data , Survival Analysis , Survival Rate , Time Factors , Treatment OutcomeABSTRACT
No disponible
Subject(s)
Male , Humans , Angioplasty, Balloon, Coronary , Atherectomy, Coronary/methods , Calcinosis/surgery , Coronary Stenosis/surgery , Coronary Stenosis/therapy , Stents , Coronary Angiography , Follow-Up Studies , Time FactorsABSTRACT
Data on the long-term prognosis of acute myocardial infarction (AMI) in young patients are limited. This study investigated long-term survival and risk predictors in a series of 108 consecutive patients =40 years old who represented 4% of 2,644 patients who presented with AMI at a single center between June 1986 and April 1992. Four patients died soon after admission. The overall mortality rate of the 104 survivors was 25.5% at 15 years. The mortality rate was higher in patients who had type 1 diabetes mellitus (p = 0.01), long-term excessive alcohol intake (p = 0.035), peripheral arterial disease (p = 0.004), previous AMI (p = 0.04), anterior AMI (p = 0.01), and depressed left ventricular ejection fraction (p <0.0001). Cumulative survival rates (Kaplan-Meier analysis) at 1, 5, 10, and 15 years were 99%, 95%, 86%, and 75%, respectively. Event-free survival rates (death, AMI, coronary intervention, severe angina pectoris, malignant arrhythmias, and congestive heart failure) at the same times were 88%, 76%, 60%, and 43%, respectively. The strongest independent predictors of the long-term mortality rate were ejection fraction =45% (odds ratio 4.4, 95% confidence interval 1.6 to 12.4, p <0.001) and peripheral arterial disease (odds ratio 45.9, 95% confidence interval 3.79 to 555, p <0.0001). These data suggest that the long-term prognosis and functional status of young patients who have AMI are not benign, especially when ejection fraction is decreased or peripheral atherosclerotic disease is present.
Subject(s)
Myocardial Infarction , Adult , Age Factors , Female , Humans , Male , Myocardial Infarction/diagnosis , Myocardial Infarction/epidemiology , Myocardial Infarction/therapy , Prognosis , Prospective Studies , Time FactorsABSTRACT
Direct connections between normal distal coronary arteries are rarely detected with angiography. In a 67-year-old man a diagnosis of intercoronary arterial continuity was established after ruling out collateral circulation secondary to coronary obstruction. Published reports of similar cases are reviewed.
Subject(s)
Arterio-Arterial Fistula/diagnostic imaging , Coronary Vessel Anomalies/diagnostic imaging , Aged , Humans , Male , RadiographyABSTRACT
La intercomunicación distal entre arterias coronarias normales es una observación angiográfica extremadamente rara. Un varón de 67 años de edad fue diagnosticado de conexión intercoronaria distal tras descartar que se tratara de circulación colateral secundaria a la obstrucción de un vaso. Se revisa la bibliografía al respecto (AU)
No disponible