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1.
Obama catapults patient-empowered Precision Medicine.
Fox, Jeffrey L.
Nat Biotechnol ; 33(4): 325, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25850042

Subject(s)
Crowdsourcing/methods , Databases, Genetic , Government Programs , Patient Participation/methods , Precision Medicine/methods , Social Media , Humans , United States
2.
Agricultural probiotics enter spotlight.
Fox, Jeffrey L.
Nat Biotechnol ; 33(2): 122, 2015 Feb.
Article in English | MEDLINE | ID: mdl-25658267

Subject(s)
Agriculture , Drug Industry/economics , Probiotics/economics , Humans , Plant Development/drug effects
3.
Technology comes to typing.
Fox, Jeffrey L.
Nat Biotechnol ; 32(11): 1081-4, 2014 Nov.
Article in English | MEDLINE | ID: mdl-25380436

ABSTRACT

As mass spectrometry makes inroads into pathogen identification in the clinical laboratory, deep sequencing - even nanopore sequencing - is waiting in the wings. Jeffrey L. Fox investigates.


Subject(s)
Bacterial Typing Techniques , High-Throughput Nucleotide Sequencing , Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization , Humans , Nanopores
4.
Second MRSA antibiotic reaches the market.
Fox, Jeffrey L.
Nat Biotechnol ; 32(10): 972, 2014 Oct.
Article in English | MEDLINE | ID: mdl-25299909

Subject(s)
Anti-Bacterial Agents , Glycopeptides , Methicillin-Resistant Staphylococcus aureus , Staphylococcal Infections/drug therapy , Drug Approval , Humans , Lipoglycopeptides
5.
FDA launches two research centers with academia.
Fox, Jeffrey L.
Nat Biotechnol ; 32(7): 601, 2014 Jul.
Article in English | MEDLINE | ID: mdl-25004209

Subject(s)
Biotechnology/organization & administration , Clinical Trials as Topic/methods , Entrepreneurship/organization & administration , Government Programs/organization & administration , Government Regulation , Research/organization & administration , United States Food and Drug Administration , United States
6.
First vanguard anti-MRSA agent approved.
Fox, Jeffrey L.
Nat Biotechnol ; 32(7): 603, 2014 Jul.
Article in English | MEDLINE | ID: mdl-25004211

Subject(s)
Anti-Bacterial Agents/therapeutic use , Drug Approval , Drug Industry , Methicillin-Resistant Staphylococcus aureus/drug effects , Staphylococcal Infections/drug therapy , Teicoplanin/analogs & derivatives , Evidence-Based Medicine , Humans , Teicoplanin/therapeutic use , United States , United States Food and Drug Administration
7.
NIH 'hubs' aid translation.
Fox, Jeffrey L.
Nat Biotechnol ; 32(7): 608, 2014 Jul.
Article in English | MEDLINE | ID: mdl-25004219

Subject(s)
Financing, Government/economics , Government Programs/economics , National Institutes of Health (U.S.)/economics , Translational Research, Biomedical/economics , United States
8.
Indiana jumps the biosimilars gun.
Fox, Jeffrey L.
Nat Biotechnol ; 32(5): 406, 2014 May.
Article in English | MEDLINE | ID: mdl-24811502

Subject(s)
Biosimilar Pharmaceuticals , Drug Industry/legislation & jurisprudence , Humans , Indiana , United States , United States Food and Drug Administration
9.
Fraunhofer to mine Sanofi microbial collection.
Fox, Jeffrey L.
Nat Biotechnol ; 32(4): 305, 2014 Apr.
Article in English | MEDLINE | ID: mdl-24714464

Subject(s)
Bacteria , Biological Products , Biological Specimen Banks , Anti-Infective Agents , Biomedical Research , California , Drug Industry , Germany , Internationality , Paris
10.
Master Protocol for squamous cell lung cancer readies for launch.
Fox, Jeffrey L.
Nat Biotechnol ; 32(2): 116-8, 2014 Feb.
Article in English | MEDLINE | ID: mdl-24509741

Subject(s)
Carcinoma, Squamous Cell/drug therapy , Drug Industry , Lung Neoplasms/drug therapy , Clinical Trials as Topic , Humans , United States , United States Food and Drug Administration
11.
Anti-infective monoclonals step in where antimicrobials fail.
Fox, Jeffrey L.
Nat Biotechnol ; 31(11): 952-4, 2013 Nov.
Article in English | MEDLINE | ID: mdl-24213755

Subject(s)
Anti-Infective Agents/pharmacology , Antibodies, Monoclonal/pharmacology , Drug Industry/trends , Animals , Antibodies, Monoclonal, Humanized/pharmacology , Drug Resistance , Humans , Palivizumab
12.
Mars collaborates to sequence Africa's neglected food crops.
Fox, Jeffrey L.
Nat Biotechnol ; 31(10): 867, 2013 Oct.
Article in English | MEDLINE | ID: mdl-24104740

Subject(s)
Biotechnology , Cooperative Behavior , Crops, Agricultural/genetics , Food , Sequence Analysis, DNA , Africa , Biodiversity , European Union , Genome, Plant/genetics
13.
Volunteer GM wheat, mischief or carelessness?
Fox, Jeffrey L.
Nat Biotechnol ; 31(8): 669-70, 2013 Aug.
Article in English | MEDLINE | ID: mdl-23929328

Subject(s)
Glycine/analogs & derivatives , Plants, Genetically Modified/drug effects , Triticum/genetics , Glycine/pharmacology , Humans , Plants, Genetically Modified/growth & development , Triticum/drug effects , Triticum/growth & development , United States , United States Department of Agriculture , Glyphosate
14.
Fecal transplants to follow FDA rules.
Fox, Jeffrey L.
Nat Biotechnol ; 31(7): 583, 2013 Jul.
Article in English | MEDLINE | ID: mdl-23839135

Subject(s)
Feces/microbiology , United States Food and Drug Administration/legislation & jurisprudence , Humans , Microbiota , United States
15.
$350 million in new funding for brain research.
Fox, Jeffrey L.
Nat Biotechnol ; 31(6): 480, 2013 Jun.
Article in English | MEDLINE | ID: mdl-23752420

Subject(s)
Brain/physiology , Financing, Government , Research/economics , Brain/immunology , Europe , Humans , United States
16.
FDA moves on breakthrough therapies.
Fox, Jeffrey L.
Nat Biotechnol ; 31(5): 374, 2013 May.
Article in English | MEDLINE | ID: mdl-23657379

Subject(s)
Aminophenols/therapeutic use , Aminopyridines/therapeutic use , Benzodioxoles/therapeutic use , Drug Approval/organization & administration , Neoplasms/drug therapy , Quinolones/therapeutic use , Terminal Care/trends , United States
17.
Antimicrobial peptides stage a comeback.
Fox, Jeffrey L.
Nat Biotechnol ; 31(5): 379-82, 2013 May.
Article in English | MEDLINE | ID: mdl-23657384

Subject(s)
Antimicrobial Cationic Peptides/adverse effects , Antimicrobial Cationic Peptides/therapeutic use , Bacterial Infections/drug therapy , Anti-Infective Agents/adverse effects , Anti-Infective Agents/therapeutic use , Drug Approval , Humans , United States
18.
Sequestration to slash research grants and delay biosimilars.
Fox, Jeffrey L.
Nat Biotechnol ; 31(4): 271, 2013 Apr.
Article in English | MEDLINE | ID: mdl-23563405

Subject(s)
Biosimilar Pharmaceuticals/economics , Budgets , Financing, Organized/economics , Research Support as Topic/economics , Animals , Biotechnology/economics , Federal Government , Humans , United States , United States Environmental Protection Agency , United States Food and Drug Administration
19.
All conflicts of interest in one site.
Fox, Jeffrey L.
Nat Biotechnol ; 31(2): 97, 2013 Feb.
Article in English | MEDLINE | ID: mdl-23392498

Subject(s)
Databases, Factual , Internet , Conflict of Interest/economics , Humans
20.
Anthrax drug first antibacterial mAb to win approval.
Fox, Jeffrey L.
Nat Biotechnol ; 31(1): 8, 2013 Jan.
Article in English | MEDLINE | ID: mdl-23302914

Subject(s)
Anthrax/therapy , Antibodies, Monoclonal/therapeutic use , Drug Approval/legislation & jurisprudence , Biological Warfare , Biotechnology , Drug Industry , Humans , United States , United States Food and Drug Administration
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