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1.
J Allergy Clin Immunol Pract ; 5(2): 352-357.e1, 2017.
Article in English | MEDLINE | ID: mdl-27888035

ABSTRACT

BACKGROUND: Food allergy (FA) is a prevalent condition in the United States, but little is known about its phenotypes in racial minority groups. OBJECTIVE: The objective of this study was to characterize disease phenotypes and disparities in health care utilization among African American (AA), Hispanic, and white children with FA. METHODS: We conducted a large, 2-center, retrospective cohort study of children aged 0-17 years with FA seen in allergy/immunology clinics at 2 urban tertiary care centers in the United States. We used multiple logistic regression analyses adjusted for age, gender, and insurance. RESULTS: The cohort of 817 children was composed of 35% AA, 12% Hispanic, and 53% non-Hispanic white. Compared with non-Hispanic white children, AA children had significantly higher odds of having asthma and eczema (P < .01), and significantly higher odds of allergy to wheat, soy, corn, fish, and shellfish (P < .01). Compared with non-Hispanic white children, Hispanic children had significantly higher odds of allergy to corn, fish, and shellfish (P < .01), and higher odds of eczema (P < .01), but a similar rate of asthma (P = .44). In this cohort, 55%, 18%, and 11% of AA, Hispanic, and white children were covered by Medicaid, respectively (P < .00001). Compared with whites, AA and Hispanic children had a shorter duration of follow-up for FA with an allergy specialist and higher rates of FA-related anaphylaxis and emergency department visits (P < .01). CONCLUSIONS: FA phenotypes and health care utilization differ among children of different racial and/or ethnic backgrounds in the United States that put AA and Hispanic children at higher risks of adverse outcome than white children. These differences include coexistent atopic conditions, less well recognized food allergens, and higher rates of anaphylaxis.


Subject(s)
Black or African American , Food Hypersensitivity/ethnology , Food Hypersensitivity/immunology , Healthcare Disparities/ethnology , Hispanic or Latino , Minority Groups , Patient Acceptance of Health Care/ethnology , White People , Adolescent , Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , Prevalence , Retrospective Studies , United States/epidemiology
2.
Semin Dial ; 24(3): 338-40, 2011.
Article in English | MEDLINE | ID: mdl-21682774

ABSTRACT

A 28-year-old woman with end-stage renal disease maintained on peritoneal dialysis developed a hyperpigmented macular pruritic rash on multiple parts of her body associated with an eosinophilia of 22%. The consulting allergist suspected a silicone allergy from the peritoneal dialysis catheter. A patch test confirmed this diagnosis. Treatment with both topical and systemic steroids was ineffective. Following a living nonrelated renal transplant and removal of the catheter the rash and eosinophilia resolved.


Subject(s)
Catheters, Indwelling/adverse effects , Dermatitis, Allergic Contact/diagnosis , Eosinophilia/etiology , Peritoneal Dialysis/instrumentation , Pruritus/etiology , Silicones/adverse effects , Adult , Exanthema/etiology , Female , Humans , Kidney Failure, Chronic/therapy , Patch Tests , Peritoneal Dialysis/adverse effects
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