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Vet Hum Toxicol ; 43(2): 109-11, 2001 Apr.
Article in English | MEDLINE | ID: mdl-11308118

ABSTRACT

The mycotoxin fumonisin B1 (FB1) causes a variety of health problems in animals, while epidemiological evidence suggests it is linked to human esophageal cancer. We investigated the carry-over of FB1 into bovine milk using the isolated perfused bovine udder. Two mg of FB1 was injected into the perfusion blood of 3 udders, and milk and perfused serum levels were determined for 150 min. FB1 passed through the mammary barrier into the milk, but in such low concentrations as to present a negligible risk for consumers.


Subject(s)
Carboxylic Acids/pharmacokinetics , Carcinogens, Environmental/pharmacokinetics , Cattle/metabolism , Fumonisins , Mammary Glands, Animal/metabolism , Milk/metabolism , Mycotoxins/pharmacokinetics , Animals , Cattle/blood , Female , Humans , In Vitro Techniques , Injections/veterinary , Perfusion/veterinary
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