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Semin Ophthalmol ; 24(6): 225-30, 2009.
Article in English | MEDLINE | ID: mdl-19954371

ABSTRACT

PURPOSE: To evaluate the effect of intravitreal injection of the combination of Triamcinolone Acetonide and Bevacizumab in patients with diabetic macular edema. MATERIALS AND METHODS: Twenty seven eyes of 17 patients with diabetic macular edema were treated with an intravitreal injection of triamcinolone acetonide (2 mg) combined with bevacizumab (1.25 mg). RESULTS: During the 6 months follow-up period 24 eyes (89%) had to repeat the treatment according to the monthly follow-up examination.The mean visual acuity and the central macular thickness improved significantly (P<0.05) throughout the follow-up period. CONCLUSION: Intravitreal combination of Triamcinolone Acetonide and Bevacizumab seems to be effective in improving visual acuity and macular edema in patients with diabetic maculopathy.


Subject(s)
Angiogenesis Inhibitors/administration & dosage , Antibodies, Monoclonal/administration & dosage , Diabetic Retinopathy/drug therapy , Immunosuppressive Agents/administration & dosage , Macular Edema/drug therapy , Triamcinolone Acetonide/administration & dosage , Aged , Antibodies, Monoclonal, Humanized , Bevacizumab , Diabetic Retinopathy/pathology , Drug Combinations , Female , Humans , Injections, Intraocular , Macula Lutea/drug effects , Macula Lutea/pathology , Macular Edema/pathology , Male , Middle Aged , Prospective Studies , Visual Acuity/drug effects
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