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1.
Prog Biophys Mol Biol ; 110(2-3): 390-6, 2012.
Article in English | MEDLINE | ID: mdl-22910435

ABSTRACT

Pre-cordial thump (PT) relies on cardiac mechano-electric transduction to transform mechanically-delivered energy into an electrophysiologically relevant stimulus. Its use for emergency resuscitation has declined recent years, amidst concerns about effectiveness and side-effects. In addition, there is insufficient knowledge about bio-mechanical properties and mechanisms of PT. Using a PT-mechanics recorder, we measured PT off-patient among healthcare professionals (n = 58) in North-East Italy, and related this to retrospective information on self-reported PT outcomes. Impact-speed and peak-force were 4.7 ± 1.3 m s⁻¹ (2.2-7.8 m s⁻¹) and 394 ± 110 N (202-648 N), respectively. Average self-reported cardioversion rate by PT was 35%. No adverse events were stated. All but 3 of PT providers with self-reported cardioversion rates ≥50% had pre-impact fist-speeds of ≥3.7 m s⁻¹. In comparison with previously-reported data from UK and US (n = 22 each), self-reported success-rates and pre-impact fist-speeds were more similar to US (PT-induced cardioversion rate 27.7%; fist-speed 4.17 ± 1.68 m s⁻¹) than to UK participants (PT-induced cardioversion rate 13.3%; fist-speed 1.55 ± 0.68 m s⁻¹). Small cohort-size, retrospective nature of data-gathering, and 'self-selection bias' (participants who have used PT on patients) limits the extent to which firm conclusions can be drawn. Observations are compatible, though, with the possibility that pre-impact fist-speed may affect success-rate of PT. Thus, where PT is used for acute resuscitation, it is delivered because it is immediately 'at hand'. Negative side effects are rare or absent in witnessed cardiac arrest cases. Pre-impact fist-speed may be a determinant of outcome, and this could be trained using devices suitable for self-assessment.


Subject(s)
Cardiopulmonary Resuscitation/methods , Emergency Service, Hospital , Health Personnel , Heart , Mechanical Phenomena , Outcome Assessment, Health Care , Cardiopulmonary Resuscitation/instrumentation , Humans , Italy
2.
Resuscitation ; 80(1): 17-23, 2009 Jan.
Article in English | MEDLINE | ID: mdl-19010581

ABSTRACT

BACKGROUND: Prospective data on pre-cordial thump (PT), one of the fastest possible resuscitative manoeuvres, are scant, particularly in out-of-hospital (OOH) cardiac arrest (CA). METHODS: In this study, conducted in the Pordenone-province (north-east Italy), suspected OOH-CA victims were connected to a cardiac monitor and, upon confirmation of CA, subjected to a swift PT before any other resuscitatory intervention, without notable delay in other procedures. Investigation targets were: (i) effects on heart rhythm, (ii) return of spontaneous circulation (ROSC), (iii) hospital discharge, (iv) presence of adverse effects. Outcomes were additionally grouped by presenting rhythms into ventricular tachyarrhythmias (CA(VF/VT)), pulseless electrical activity (CA(PEA)), and asystole (CA(AS)). RESULTS: Out of 144 OOH-CA cases, PT had no effect on heart rhythm in 138 patients (CA(VF/VT)-23/24; CA(PEA)-41/42; CA(AS)-74/78). In 112 of the 138 non-responders, ROSC was neither achieved by other interventions (CA(VF/VT)-13/23; CA(PEA)-38/41; CA(AS)-61/74); overall survival was 5.6% (CA(VF/VT)-16.7%; CA(PEA)-0%; CA(AS)-5.1%). PT caused ROSC in 3 patients with witnessed CA(AS) (time-to-intervention <3 min), representing one quarter of ROSC among witnessed CA victims. Survival of PT-induced ROSC patients (2/3) was certainly no worse than among PT-irresponsive ROSC patients (6 of 28). Overall, one quarter of patients, discharged from hospital, had been resuscitated by PT. No adverse effects of PT were observed. CONCLUSIONS: PT can be combined with standard resuscitatory interventions without significant time-delay or apparent side effects. PT efficacy in CA(VF/VT) and CA(PEA) is lacking. However, PT may offer potential for the increasing proportion of asystolic OOH-CA, in particular when witnessed.


Subject(s)
Cardiopulmonary Resuscitation/methods , Heart Arrest/therapy , Physical Stimulation/methods , Aged , Aged, 80 and over , Emergency Medical Services/methods , Emergency Medical Services/statistics & numerical data , Female , Heart Arrest/mortality , Humans , Italy , Male , Middle Aged , Patient Discharge , Prospective Studies , Survival Analysis , Treatment Outcome
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