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Tenosynovitis caused by a novel nontuberculous Mycobacterium species initially misidentified as a member of the Mycobacterium tuberculosis complex.
Simner, Patricia J; Hyle, Emily P; Buckwalter, Seanne P; Branda, John A; Brown-Elliott, Barbara A; Franklin, Jameelah; Toney, Nadege C; de Man, Tom J B; Wallace, Richard J; Vasireddy, Ravikiran; Gandhi, Rajesh T; Wengenack, Nancy L.
J Clin Microbiol ; 52(12): 4414-8, 2014 Dec.
Article in English | MEDLINE | ID: mdl-25253791

ABSTRACT

We present a case of tenosynovitis caused by a novel, slowly growing, nonchromogenic, nontuberculous mycobacterium (NTM). Originally misidentified as Mycobacterium tuberculosis complex, the NTM cross-reacts with the M. tuberculosis complex nucleic acid hybridization probe, a M. tuberculosis gamma interferon release assay, and is closely related to M. tuberculosis by 16S rRNA gene sequencing.


Subject(s)
Mycobacterium Infections, Nontuberculous/diagnosis , Mycobacterium Infections, Nontuberculous/microbiology , Nontuberculous Mycobacteria/isolation & purification , Tenosynovitis/diagnosis , Tenosynovitis/microbiology , Anti-Bacterial Agents/pharmacology , Cluster Analysis , DNA, Bacterial/chemistry , DNA, Bacterial/genetics , DNA, Ribosomal/chemistry , DNA, Ribosomal/genetics , Diagnostic Errors , Diagnostic Tests, Routine , Female , Humans , Interferon-gamma Release Tests , Middle Aged , Molecular Sequence Data , Mycobacterium Infections, Nontuberculous/pathology , Nontuberculous Mycobacteria/classification , Nontuberculous Mycobacteria/genetics , Nucleic Acid Hybridization , Phylogeny , RNA, Ribosomal, 16S/genetics , Sequence Analysis, DNA , Tenosynovitis/pathology
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