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1.
J Behav Med ; 24(5): 423-39, 2001 Oct.
Article in English | MEDLINE | ID: mdl-11702358

ABSTRACT

This study examined the moderating effects of sociotropic cognition (SC), a nondefensive need for approval, on stress-induced cardiovascular responsiveness (CVR) in women. Sixty-seven college-age females had blood pressure (BP) and heart rate (HR) monitored during baseline, anticipation, story-telling (where participants were randomly assigned to a low or high threat condition), and recovery periods. SC showed a positive association with CVR only in the high interpersonal threat context during task and early stages of the recovery periods. SC was positively correlated with such variables as anxiety, ruminative style, dysphoria, and anger. This is the first report examining the moderating effects of SC on interpersonal stress-induced CVR prior to, during, and following a task, using an explicit manipulation of social evaluation. The data help define risk factors for CVR in women, which may aid in the understanding of how emotions and stress affect physical health and well-being.


Subject(s)
Cognition , Hemodynamics , Interpersonal Relations , Stress, Psychological/physiopathology , Students/psychology , Women/psychology , Adolescent , Adult , Blood Pressure , Emotions , Female , Heart Rate , Humans , Random Allocation , Sampling Studies , Social Behavior , Social Environment , Stress, Psychological/psychology , Women's Health
2.
Psychosom Med ; 63(3): 463-9, 2001.
Article in English | MEDLINE | ID: mdl-11382274

ABSTRACT

OBJECTIVE: Research and theory link an interpersonal conflict model to cardiovascular disease. Specifically, persons scoring high on cynical hostility and social defensiveness are thought to manifest a defensive need for approval while harboring basic distrust and hostility toward those who could provide such approval. The objective of this study was to assess whether angiographically determined coronary artery disease (CAD) was associated with this combination of high cynical hostility and high social defensiveness. METHODS: Fifty-nine male patients of a Veterans Administration Medical Center (86% white, mean age = 59.9 years) participated in the study on the day before their angiographic procedure; these men filled out the Cook-Medley Hostility Scale and the Marlowe-Crowne Social Desirability Scale (social defensiveness). They subsequently were categorized as having defensive hostility (DH), high hostility (HH), high social defensiveness (SD), or low psychosocial risk (LRisk; low on both scales). RESULTS: The four groups did not differ significantly on risk factor status or health status. As predicted, a preplanned contrast showed that the DH group's mean number of arteries with at least 50% blockage (mean = 2.5) differed significantly from the combined means of the other groups. The HH and SD groups did not differ from the LRisk group. CONCLUSIONS: When combined with other reports, the approach-avoidance interpersonal conflict model holds the promise of providing additional information about the psychosocial factors contributing to CAD development among men with high cynical hostility.


Subject(s)
Coronary Disease/psychology , Defense Mechanisms , Hostility , Veterans/psychology , Adult , Aged , Coronary Disease/diagnosis , Coronary Disease/epidemiology , Humans , Hypertension/diagnosis , Hypertension/epidemiology , Male , Middle Aged , Social Desirability
3.
Psychother Psychosom ; 64(3-4): 156-61, 1995.
Article in English | MEDLINE | ID: mdl-8657847

ABSTRACT

We examined the interaction of a defensive need for approval with cynical hostility, in the prediction of pressor and heart rate reactivity to a stressful mental arithmetic task. For both systolic blood pressure and heart rate, analyses revealed the predicted interaction between defensiveness and cynical hostility; subsequent analyses showed significant correlations of defensiveness with systolic blood pressure and heart rate reactivity only among the high cynical hostility subjects. These analyses support the theory and empirical findings linking the conflicting traits of cynical hostility and defensiveness to cardiovascular reactivity and, quite possibly, to stress-related coronary disease.


Subject(s)
Cardiovascular Physiological Phenomena , Coronary Disease/psychology , Hostility , Stress, Psychological , Adolescent , Adult , Analysis of Variance , Blood Pressure/physiology , Coronary Disease/physiopathology , Heart Rate/physiology , Humans , Male , Regression Analysis , Systole
4.
Child Dev ; 63(3): 711-24, 1992 Jun.
Article in English | MEDLINE | ID: mdl-1600831

ABSTRACT

Visual expectation was assessed in 103 black 6.5-month-olds using Haith, Hazan, and Goodman's paradigm and related to performance on standard developmental assessments and tests of information processing skill. As expected, percent anticipations was higher and RT lower than in 3.0-month-olds previously tested. Split-half and left-right correlations for the RT measures were moderate and similar to those previously reported, as was split-half reliability for percent anticipations. The 2 RT measures were related to fixation duration on both visual recognition memory (VRM) and cross-modal transfer, suggesting moderate cross-task and cross-age consistency in processing speed. Percent anticipations and baseline RT each contributed independently to the prediction of VRM novelty preference. Data from a factor analysis suggested 3 dimensions of cognitive function: processing speed, developmental level, and memory/attention. These findings suggest that the visual expectation paradigm provides a reliable new approach for assessing cognitive processing efficiency and attention during infancy.


Subject(s)
Black or African American/psychology , Mental Processes , Psychology, Child , Set, Psychology , Urban Population , Attention , Cohort Studies , Fetal Alcohol Spectrum Disorders/diagnosis , Fetal Alcohol Spectrum Disorders/psychology , Humans , Infant , Longitudinal Studies , Neurologic Examination , Pattern Recognition, Visual , Reaction Time
5.
Antimicrob Agents Chemother ; 31(10): 1461-4, 1987 Oct.
Article in English | MEDLINE | ID: mdl-2893584

ABSTRACT

The effects of vancomycin, gentamicin, and combination vancomycin-gentamicin treatments on alanine aminopeptidase (AAP) and beta 2-microglobulin (beta 2M) elimination in 30 hospitalized patients were assessed and compared with elimination in a control group. Twenty-four-hour urine excretion values for AAP and beta 2M were determined on treatment day 1 and day 5 for patients receiving the three treatment regimens and for the control group. AAP excretion values for the vancomycin-treated group were not found to be statistically different from those of the control group. Both the gentamicin and the vancomycin-gentamicin groups had statistically higher AAP excretion values on treatment day 1 as well as on treatment day 5 when compared with the vancomycin and control groups. AAP excretion on day 5 of treatment was highest for the vancomycin-gentamicin group. Overall, beta 2M elimination was variable in all treatment groups. Although the beta 2M values were elevated as early as day 1 in all treatment groups, they were significantly elevated only in the vancomycin-gentamicin group on day 1 and only in the gentamicin group on day 5 compared with the vancomycin and the control groups. AAP appears to be a sensitive indicator of renal tubular damage. The combination of vancomycin and gentamicin results in greater AAP excretion than does either agent alone.


Subject(s)
Aminopeptidases/urine , Gentamicins/adverse effects , Vancomycin/adverse effects , beta 2-Microglobulin/urine , Adolescent , Adult , Aged , Aged, 80 and over , CD13 Antigens , Female , Humans , Male , Middle Aged
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