ABSTRACT
According to a population-based estimate, chronic pelvic pain (CPP) affects approximately 15% of women aged 18-50. The psychosocial impact of CPP is reflected in mood disturbance, disruption of normal activity and relationships as well as pain. Identification of psychosocial factors as cause or effect remains problematic. Results of a study of 105 women with CPP using the British version of the SF-36 Health Survey Questionnaire are presented, together with analyses of face validity and reliability. While generally reflecting health status, specific problems with the questionnaire are identified related to the episodic nature of pelvic pain, and avoidance as a means of preventing pain exacerbations. Health economic analyses relating to CPP are reviewed and the implications for future directions in treatment strategy are discussed in the context of limited options of proven efficacy.
Subject(s)
Pelvic Pain/economics , Pelvic Pain/psychology , Adolescent , Adult , Child , Child Abuse, Sexual/psychology , Child, Preschool , Chronic Disease , Female , Health Care Costs , Health Status Indicators , Humans , Middle Aged , Mood Disorders/complications , Psychophysiologic Disorders/complications , Quality of Life , Surveys and Questionnaires , United KingdomABSTRACT
The Yunis-Varon syndrome is a rare hereditary disorder with ectodermal and skeletal anomalies that include agenesis or hypoplasia of the clavicles, craniofacial disproportion with severe micrognathia, digital anomalies, prenatal and postnatal growth deficiency, and neonatal death. Only 12 cases have been reported in the literature. Although neonatal death is a significant feature of this syndrome, two case reports describe children, both males, who were 30 months and 3 years of age at the time of investigation. The 30-month-old child was reexamined at 11 years of age, and had further clinical and radiologic features that included hypodontia, impacted permanent teeth, spinal defects, cardiomegaly, bilateral hearing loss, and metatarsus adductus. Children who survive the neonatal period and continue to thrive with many of the features of the Yunis-Varon syndrome as well as the new features described in this article may not have a distinct yet related syndrome.
Subject(s)
Anodontia , Cardiomegaly , Spinal Diseases , Tooth, Impacted , Abnormalities, Multiple , Anodontia/pathology , Cardiomegaly/pathology , Child , Fingers/abnormalities , Growth Disorders/pathology , Humans , Intellectual Disability , Male , Malocclusion/pathology , Mandible/abnormalities , Micrognathism/pathology , Spinal Diseases/pathology , Syndrome , Toes/abnormalities , Tooth Abnormalities/pathology , Tooth, Impacted/pathologyABSTRACT
Perirenal bleeding following biopsy was assessed in 25 consecutive cases using computerized axial tomography (CT) scanning. Perirenal hematomas were found in 15 patients (60%). In 8 patients the hematomas were moderate or large in size. There was no correlation between the clinical findings, fall in hemoglobin, presence of macroscopic hematuria and the finding of perirenal hematoma by CT scanning.
