ABSTRACT
AIM: To examine the association of distance-near disparity with neurological disease in children with intermittent exotropia. METHODS: A retrospective analysis was performed of the medical records of all children with intermittent exotropia examined at the Arkansas Children's Hospital between 1989 and 2002. The study group consisted of children with intermittent exotropia who had a near deviation that exceeded the deviation at distance by at least 10 prism dioptres. The control group consisted of children with intermittent exotropia who had a distance deviation greater than or equal to the deviation at near. The main outcome measures were the prevalence of neurological abnormalities in the study and control groups. RESULTS: Among the 29 patients in the study group, 19 (66%) had a history of concurrent neurological abnormalities. Associated neurological conditions included developmental delay (10 patients), attention deficit disorder (four patients), cerebral palsy (four patients), history of intracranial haemorrhage (four patients), periventricular leucomalacia (three patients), seizures (two patients), cortical visual impairment (two patients), hydrocephalus (one patient), history of anoxic brain damage (one patient), history of encephalitis (one patient), and autism (one patient). Among the 37 patients in the control group, seven (19%) had a history of concurrent neurological abnormalities. The difference in the prevalence of neurological disease between the study group and the control group was significant (p = 0.0002). CONCLUSION: Intermittent exotropia increasing with near fixation is associated with neurological disease in children.
Subject(s)
Exotropia/etiology , Nervous System Diseases/complications , Adolescent , Case-Control Studies , Chi-Square Distribution , Child , Child, Preschool , Depth Perception , Exotropia/diagnosis , Female , Fixation, Ocular , Humans , Male , Nervous System Diseases/diagnosis , Retrospective Studies , Vision TestsABSTRACT
AIM: To examine the association of distance-near disparity with neurological disease in children with intermittent exotropia. METHODS: A retrospective analysis was performed of the medical records of all children with intermittent exotropia examined at the Arkansas Children's Hospital between 1989 and 2002. The study group consisted of children with intermittent exotropia who had a near deviation that exceeded the deviation at distance by at least 10 prism dioptres. The control group consisted of children with intermittent exotropia who had a distance deviation greater than or equal to the deviation at near. The main outcome measure was the prevalence of neurological abnormalities in the study and control groups. RESULTS: Among the 29 patients in the study group, 19 (66%) had a history of concurrent neurological abnormalities. Associated neurological conditions included developmental delay (10 patients), attention deficit disorder (four patients), cerebral palsy (four patients), history of intracranial haemorrhage (four patients), periventricular leucomalacia (three patients), seizures (two patients), cortical visual impairment (two patients), hydrocephalus (one patient), history of anoxic brain damage (one patient), history of encephalitis (one patient), and autism (one patient). Among the 37 patients in the control group, seven (19%) had a history of concurrent neurological abnormalities. The difference in the prevalence of neurological disease between the study group and the control group was significant (p=0.0002). CONCLUSION: Intermittent exotropia increasing with near fixation is associated with neurological disease in children.
Subject(s)
Exotropia/etiology , Nervous System Diseases/complications , Adolescent , Case-Control Studies , Chi-Square Distribution , Child , Child, Preschool , Depth Perception , Exotropia/diagnosis , Female , Fixation, Ocular , Humans , Male , Nervous System Diseases/diagnosis , Retrospective Studies , Vision TestsSubject(s)
Abnormalities, Multiple/diagnosis , Brain Stem/abnormalities , Cranial Fossa, Posterior/abnormalities , Duane Retraction Syndrome/complications , Hearing Disorders/complications , Klippel-Feil Syndrome/complications , Brain Stem/pathology , Cranial Fossa, Posterior/pathology , Female , Humans , Infant , Magnetic Resonance ImagingABSTRACT
BACKGROUND: A subgroup of patients with intermittent exotropia have a high AC/A ratio, which places them at risk for esotropia at near after surgical treatment of their distance deviation. METHODS: A retrospective review of six patients with intermittent exotropia and a high AC/A ratio who were simultaneously treated with lateral rectus recessions to fully correct their exotropia at distance and placement of posterior fixation sutures on both medial rectus muscles in hopes of preventing an esotropia at near after surgery. RESULTS: Despite the persistence of a high postoperative AC/A ratio as assessed by the gradient method, five of six patients achieved stable postoperative alignment at distance and near without bifocals. One patient required postoperative bifocal correction for intermittent esotropia at near. CONCLUSION: In patients with intermittent exotropia and a high AC/A ratio, posterior fixation of the medial rectus muscles at the time of lateral rectus recessions enables the surgeon to fully correct the distance deviation and minimizes the risk of postoperative esotropia at near.
Subject(s)
Accommodation, Ocular , Convergence, Ocular , Exotropia/surgery , Oculomotor Muscles/surgery , Child , Child, Preschool , Female , Fixation, Ocular , Humans , Male , Retrospective Studies , Vision, BinocularABSTRACT
PURPOSE: To determine the influence of underlying visual system disorders on the risk of developing strabismus in children with congenital nystagmus. METHODS: We retrospectively reviewed 82 cases of congenital nystagmus from a pediatric ophthalmology referral practice. RESULTS: Strabismus was found in 50% of children with congenital nystagmus. The prevalence of strabismus was 82% in children with bilateral optic nerve hypoplasia, 53% in patients with albinism, 36% in children with congenital retinal dystrophies, and 17% in children with idiopathic congenital nystagmus. CONCLUSION: The risk that a child with congenital nystagmus will have strabismus develop can be predicted from the nature of the underlying visual disorder.
