ABSTRACT
Standfirst Mounting interest in mental health conditions over the last two decades has been coupled with the increasing sophistication of techniques to study the brain in vivo. [Formula: see text].
Subject(s)
Brain , Mental HealthABSTRACT
One technology, long-read sequencing, and one research field, microbiome studies, have risen to prominence over the last decade. But how can one be used in the other? What changes are being wrought? And what limitations remain? [Formula: see text].
Subject(s)
High-Throughput Nucleotide Sequencing , Microbiota , Microbiota/genetics , Metagenome/genetics , Sequence Analysis, DNA , MetagenomicsABSTRACT
As a new realm of single-cell studies becomes more accessible, innovative developments in one well-established technique are driving the field towards full-coverage proteomic profiles of single cells.
Subject(s)
Proteomics , Tandem Mass Spectrometry , Chromatography, Liquid/methods , Proteomics/methods , Tandem Mass Spectrometry/methodsABSTRACT
A decade of progress in whole-genome sequencing techniques has imbued researchers with the confidence to sequence all eukaryotic life on earth. But what will be essential to their success, and what challenges await them?
Subject(s)
Genomics , Genomics/methods , Whole Genome SequencingABSTRACT
BioTechniques Editors explore the evolution of point-of-care testing over the past 2 years, inside and outside of the COVID-19 pandemic.
Subject(s)
COVID-19 , Pandemics , Point-of-Care Testing/trends , HumansABSTRACT
Amidst the development of new single-cell technologies and the implementation of multiomic approaches, two Stanford labs are spearheading a new field of research to combat cancer.
Subject(s)
Neoplasms , Humans , Neoplasms/genetics , Sequence AnalysisABSTRACT
Where 3D printing was characterized by the new technologies and machinery, 4D printing is defined by the smart materials making waves in drug development and regenerative medicine.
Subject(s)
Printing, Three-Dimensional , Regenerative MedicineABSTRACT
Metagenomic approaches have been key to successful tracing and outbreak management during the COVID-19 pandemic. How can we use this knowledge to better prepare, strategize and prevent future pandemics? [Formula: see text].
Subject(s)
COVID-19/virology , Metagenomics , Pandemics/prevention & control , Animals , Humans , SARS-CoV-2/isolation & purificationABSTRACT
New tools and increased awareness are yet to enact meaningful changes in reproducibility. Tristan Free investigates why and explores promising initiatives.
Subject(s)
Reproducibility of Results , Attitude , Humans , Publications/statistics & numerical data , Quality Control , Surveys and QuestionnairesABSTRACT
Joseph Martin and Tristan Free explore the latest developments in the T-cell-based therapy CAR-T and the challenges that need to be overcome for them to become common clinical practice.
Subject(s)
Immunotherapy, Adoptive , Humans , T-LymphocytesABSTRACT
Mass spectrometry has been used for decades and continues to be an integral part of analytical research. This feature explores its latest applications.
Subject(s)
Mass Spectrometry/methods , Molecular Biology/instrumentation , Microbiology , Nucleic Acids/chemistry , Proteins/chemistryABSTRACT
We look at how next-generation sequencing has advanced research across different disease fields, and the growing importance of open access genomic databases.
