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1.
Acta cir. bras ; 26(3): 235-241, May-June 2011. ilus, tab
Article in English | LILACS | ID: lil-583745

ABSTRACT

PURPOSE: To investigate the effectiveness of fibrin glue (laparoscopic via) into promote the hemostasis of a spleen injury on a heparinized porcine model. METHODS: Eighteen Landrace porcine were submitted to laparoscopic spleen injury and randomly distributed: GHA (heparin plus adhesive), GH (heparin without adhesive) and GS (Sham - without heparin or adhesive). Ten minutes before the surgical procedures a single IV dose (200UI/kg) of heparin sodium was administrated only to groups GHA and GH. In the GHA, adhesive was applied after the mechanical injury and recorded the time until the polymerization and clot formation. RESULTS: No significant differences occurred among the groups (Fisher test) considering the weight and surgery time. The blood amount in the abdominal cavity on GH was significantly higher in comparison to the sham group and especially with the GHA (p<0.004). No significant differences were observed in the body temperature, heart rate, cardiac output, means arterial pressure, pulmonary artery pressure during the experiment. The activated partial thromboplastin time (APTT) was lower in the GHA in comparison to GH (p<0.003). CONCLUSION: The fibrin biological adhesive applied by laparoscopy is effective for hemostasis of minor spleen injury in a porcine model under the effect of anticoagulant drug.


OBJETIVO: Investigar a eficácia da cola de fibrina (via laparoscópica) na hemostasia de uma lesão no baço de porco heparinizado. MÉTODOS: Dezoito suínos Landrace foram submetidos a lesão do baço e distribuídos aleatoriamente: GHA (heparina adesivo), GH (heparina sem adesivo) e GS (Sham - sem heparina ou adesivo). Dez minutos antes dos procedimentos uma dose única (200UI/kg) de heparina sódica (EV) foi administrada nos grupos GHA e GH. A fibrina (GHA) foi aplicada após a lesão e registrado o tempo até a polimerização e formação do coágulo. RESULTADOS: Não houve diferenças significativas entre os grupos (teste de Fisher), considerando o peso e o tempo de cirurgia. A quantidade de sangue na cavidade abdominal de GH foi significativamente maior em comparação ao GS e, especialmente, com o GHA (p<0,004). Não foram observadas diferenças significativas na temperatura corporal, frequência cardíaca, débito cardíaco, pressão arterial ou pressão da artéria pulmonar durante o experimento (20 minutos). O tempo de tromboplastina parcial ativada (TTPA) foi menor no GHA em relação ao GH (p<0,003). CONCLUSÃO: A cola de fibrina biológica aplicada por laparoscopia é eficaz para a hemostasia de lesões no baço menor em um modelo suíno sob o efeito de drogas anticoagulantes.


Subject(s)
Animals , Splenic Rupture , Swine/classification , Spleen/anatomy & histology , Laparoscopy
2.
Acta Cir Bras ; 26(3): 235-41, 2011 Jun.
Article in English | MEDLINE | ID: mdl-21537527

ABSTRACT

PURPOSE: To investigate the effectiveness of fibrin glue (laparoscopic via) into promote the hemostasis of a spleen injury on a heparinized porcine model. METHODS: Eighteen Landrace porcine were submitted to laparoscopic spleen injury and randomly distributed: GHA (heparin plus adhesive), GH (heparin without adhesive) and GS (Sham - without heparin or adhesive). Ten minutes before the surgical procedures a single IV dose (200UI/kg) of heparin sodium was administrated only to groups GHA and GH. In the GHA, adhesive was applied after the mechanical injury and recorded the time until the polymerization and clot formation. RESULTS: No significant differences occurred among the groups (Fisher test) considering the weight and surgery time. The blood amount in the abdominal cavity on GH was significantly higher in comparison to the sham group and especially with the GHA (p<0.004). No significant differences were observed in the body temperature, heart rate, cardiac output, means arterial pressure, pulmonary artery pressure during the experiment. The activated partial thromboplastin time (APTT) was lower in the GHA in comparison to GH (p<0.003). CONCLUSION: The fibrin biological adhesive applied by laparoscopy is effective for hemostasis of minor spleen injury in a porcine model under the effect of anticoagulant drug.


Subject(s)
Fibrin Tissue Adhesive/therapeutic use , Hemostasis, Surgical/methods , Spleen/injuries , Spleen/surgery , Tissue Adhesives/therapeutic use , Animals , Laparoscopy , Male , Random Allocation , Swine
3.
Surg Endosc ; 23(7): 1428-32, 2009 Jul.
Article in English | MEDLINE | ID: mdl-19263124

ABSTRACT

BACKGROUND: The aim of this study was to assess the prevalence, risks, and outcomes of injuries caused by the Veress needle described in the literature. METHODS: Iatrogenic injuries caused by Veress needle insertion during diagnostic or therapeutic laparoscopies in humans were researched, with no language restriction, in the Medline, Lilacs, Embase, Scielo, and Cochrane Library databases. The following words were combined: "Veress" or "insufflation needle" or "pneumoperitoneum needle," and "complications" or "injuries" or "lesions." The bibliographic references of the selected articles were also analyzed. We considered the following: (1) number of injuries described in the literature, (2) relationship between number of injuries and number of patients who underwent Veress needle insertion in the studies that reported Veress needle injury, (3) organs and structures injured (retroperitoneal vessels, digestive tract, and self-limited, minor injuries), and (4) outcome (death, conversion to laparotomy, laparoscopic repair, spontaneous resolution). RESULTS: Thirty-eight selected articles included 696,502 laparoscopies, with 1,575 injuries (0.23%), 126 (8%) of which involved blood vessels or hollow viscera (0.018% of all laparoscopies). Of the 98 vascular injuries, 8 (8.1%) were injuries to major retroperitoneal vessels. There were 34 other reported retroperitoneal injuries, but the authors were not specific as to which vessel was injured. Of the 28 injuries to hollow viscera, 17 were considered major injuries, i.e., 60.7% (0.0024% of the total cases assessed). CONCLUSION: The insertion of the Veress needle in the abdominal midline, at the umbilicus, poses serious risk to the life of patients. Therefore, further studies should be conducted to investigate alternative sites for Veress needle insertion.


Subject(s)
Blood Vessels/injuries , Gastrointestinal Tract/injuries , Intraoperative Complications/etiology , Needles/adverse effects , Pneumoperitoneum, Artificial/instrumentation , Punctures/adverse effects , Embolism, Air/etiology , Equipment Design , Female , Fetal Death/etiology , Hemorrhage/etiology , Hemorrhage/mortality , Humans , Insufflation/instrumentation , Intraoperative Complications/epidemiology , Intraoperative Complications/surgery , Laparoscopy , Laparotomy , Peritonitis/etiology , Pregnancy , Prevalence , Urinary Bladder/injuries
4.
Arq. gastroenterol ; 45(4): 319-322, out.-dez. 2008. ilus, graf
Article in English | LILACS | ID: lil-502142

ABSTRACT

BACKGROUND: Two-layer intestinal anastomosis increases the inflammatory response while single-layer anastomosis results in a better wound healing. However the four main kinds of stitches which may be chosen in performing single layer intestinal sutures never before had been comparatively studied. AIM: To compare the four more commonly used types of single layer surgical anastomosis sutures of the digestive tract. METHODS: Six mongrel dogs were operated, each one receiving two anastomosis: one at 30 cm from de Treitz angle - sero-submucosal technique, and the other at 60 cm - total technique. This placement was alternatively inverted. The four more commonly used types of single layer surgical anastomosis sutures of the digestive tract, namely: sero-submucosal stitches tied in the lumen, over the submucosa; sero-submucosal stitches tied in the exterior of the organ, over the serosa; total stitches tied in the lumen, over the mucosa; and total sutures tied in the exterior, over the serosa (Gambee's stitches) were tested. After euthanasia (7th post-operative day) macro and microscopic features were evaluated. Friedman's test was applied for morphometry and for evaluation of the peritoneal adhesions. RESULTS: Statistical significance was demonstrated through major residual acute inflammation and proliferation in total sutures and more profuse adhesions with the sero-submucosal stitches tied in the lumen. The sero-submucosal stitches tied in the exterior over the serosa, had excellent realignment and regeneration of the layers. CONCLUSION: The sero-submucosal stitches tied in the exterior, over the serosa, were the best ones.


RACIONAL: As anastomoses intestinais em dois planos aumentam a resposta inflamatória tecidual, enquanto que a anastomose em plano único resulta em um lúmen maior com menos danos às bordas teciduais. Entretanto, os quatro tipos de suturas mais comumente utilizados em suturas intestinais nunca foram antes estudados comparativamente. OBJETIVO: Comparar os quatro tipos de sutura do tubo digestivo em plano único mais freqüentemente utilizados para anastomoses manuais do tubo digestivo. MÉTODOS: Seis cães de raça indefinida foram operados, cada um recebendo duas anastomoses: uma a 30 cm do ângulo de Treitz - técnica sero-submucosa, e a outra a 60 cm - técnica total. Esta localização foi aleatoriamente invertida. Os quatro tipos de sutura em plano único mais freqüentemente utilizados para anastomoses manuais do tubo digestivo, denominados: pontos extramucoso atados no lúmen da víscera, sobre a submucosa, pontos extramucosos atados no exterior, sobre a serosa, pontos totais atados no lúmen, sobre a mucosa, e pontos totais especiais de Gambee atados no exterior sobre a serosa, foram testados. Eutanásia e necropsia parcial no 7º dia pós-operatório permitiu avaliação de aspectos macro e microscópicos. O teste de Friedman's foi aplicado para a morfometria e avaliação das aderências peritoniais. RESULTADOS: Foi demonstrada diferença estatisticamente significante para a inflamação residual aguda e maior proliferação nas suturas totais, bem como na maior ocorrência de aderências com pontos extramucosos atados no lúmen da víscera, sobre a submucosa. A sutura extramucosa com nós atados na serosa teve regeneração das bordas e alinhamento excelentes. CONCLUSÃO: A sutura extramucosa com nós atados na serosa mostrou-se a melhor.


Subject(s)
Animals , Dogs , Intestinal Mucosa/surgery , Suture Techniques , Serous Membrane/surgery , Anastomosis, Surgical/adverse effects , Anastomosis, Surgical/methods , Cell Division , Intestinal Mucosa/pathology , Models, Animal , Peritoneal Diseases/etiology , Serous Membrane/pathology , Surgical Wound Infection/etiology , Suture Techniques/adverse effects , Tissue Adhesions/etiology
5.
Arq Gastroenterol ; 45(4): 319-22, 2008.
Article in English | MEDLINE | ID: mdl-19148361

ABSTRACT

BACKGROUND: Two-layer intestinal anastomosis increases the inflammatory response while single-layer anastomosis results in a better wound healing. However the four main kinds of stitches which may be chosen in performing single layer intestinal sutures never before had been comparatively studied. AIM: To compare the four more commonly used types of single layer surgical anastomosis sutures of the digestive tract. METHODS: Six mongrel dogs were operated, each one receiving two anastomosis: one at 30 cm from de Treitz angle - sero-submucosal technique, and the other at 60 cm - total technique. This placement was alternatively inverted. The four more commonly used types of single layer surgical anastomosis sutures of the digestive tract, namely: sero-submucosal stitches tied in the lumen, over the submucosa; sero-submucosal stitches tied in the exterior of the organ, over the serosa; total stitches tied in the lumen, over the mucosa; and total sutures tied in the exterior, over the serosa (Gambee's stitches) were tested. After euthanasia (7th post-operative day) macro and microscopic features were evaluated. Friedman's test was applied for morphometry and for evaluation of the peritoneal adhesions. RESULTS: Statistical significance was demonstrated through major residual acute inflammation and proliferation in total sutures and more profuse adhesions with the sero-submucosal stitches tied in the lumen. The sero-submucosal stitches tied in the exterior over the serosa, had excellent realignment and regeneration of the layers. CONCLUSION: The sero-submucosal stitches tied in the exterior, over the serosa, were the best ones.


Subject(s)
Intestinal Mucosa/surgery , Serous Membrane/surgery , Suture Techniques , Anastomosis, Surgical/adverse effects , Anastomosis, Surgical/methods , Animals , Cell Division , Dogs , Intestinal Mucosa/pathology , Models, Animal , Peritoneal Diseases/etiology , Serous Membrane/pathology , Surgical Wound Infection/etiology , Suture Techniques/adverse effects , Tissue Adhesions/etiology
6.
Rev. Col. Bras. Cir ; 29(5): 311-312, set.-out. 2002.
Article in Portuguese | LILACS | ID: lil-495379

ABSTRACT

One of the most difficult challenges to surgeons is the treatment of wounds on the retro hepatic vena cava. The anatomic particularities of this venous segment make its approach and treatment difficult, contributing to a high morbidity and mortality. Several techniques have been described for the treatment of these types of lesions. In this particular case, authors have chosen the introduction of a fastened provisory intra caval prothesis, without primary suturing of the wounds. The provisory intra caval prothesis can be an option for the treatment of retro hepatic vena cava lesions.

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