Translation, Transcultural Adaptation, and Validation of the Brazilian Portuguese Version of the Body Image Disturbance Questionnaire for Scoliosis (BR-BIDQ-S).

Objective The Body Image Disturbance Questionnaire for Scoliosis (BIDQ-S) for scoliosis derives from the Body Image Disturbance Questionnaire (BIDQ) with specific adaptation for scoliosis patients. Despite its significance and applicability, this instrument has never been translated into Brazilian Portuguese. The current study aimed to translate, transculturally adapt, and validate the BIDQ-S into Brazilian Portuguese. Methods BIDQ-S was translated and culturally adapted into Brazilian Portuguese using the American Association of Orthopedic Surgeons (AAOS) criteria. The questionnaire validation relied on internal consistency and comparison with the Cobb angle, Pediatric Quality of Life Inventory (PedsQL), and Scoliosis Research Society (SRS-22). The Brazilian version (BR-)BIDQ-S validation occurred in a sample of 35 adolescents with scoliosis waiting for specialized treatment. Results Internal consistency of the BR-BIDQ-S was 0.899 according to the Cronbach's index (i.e., virtually perfect). Although BR-BIDQ-S did not correlate with the Cobb angle, it presented correlations with the Physical, Emotional, and Social domains from the PedsQL and the Function/Activity domain from the SRS-22. Conclusion BR-BIDQ-S was reliable in evaluating the body image of adolescents with scoliosis, presenting an internal consistency of 0,899 (virtually perfect). Moreover, similar to the original instrument, it correlated with PedsQL and SRS-22.

Avaliação e Ensino de Emoções com Crianças e Jovens Adultos com Autismo ou Síndrome de Down Mediado pela Família / Assessment and Teaching of Emotions with Children and Young Adults with Autism or Down Syndrome Mediated by Family / Evaluación y Enseñanza de las Emociones con Niños y Jóvenes con Autismo o Síndrome de Down Mediadas por la Familia

Resumo: Este estudo avaliou o reconhecimento (imitação, identidade e identificação) e a nomeação de estímulos emocionais de valência negativa (raiva e tristeza) e positiva (alegria e surpresa) em conjunto com a influência dos tipos de estímulos utilizados (social-feminino, social-masculino, familiar e emoji) em crianças e jovens adultos com autismo ou síndrome de Down, por meio de tarefas aplicadas pela família e mediadas por recursos tecnológicos durante a pandemia de covid-19. Participaram cinco crianças e dois jovens adultos com autismo e uma criança e dois jovens adultos com síndrome de Down. Foram implementadas tarefas de identidade, reconhecimento, nomeação e imitação, com estímulos faciais de função avaliativa (sem consequência diferencial) e de ensino (com consequência diferencial, uso de dicas e critério de aprendizagem), visando a emergência da nomeação emocional por meio do ensino das tarefas de reconhecimento. Os resultados da linha de base identificaram que, para os participantes que apresentaram menor tempo de resposta para o mesmo gênero, a diferença de tempo de resposta foi em média 57,28% menor. Em relação à valência emocional, 50% dos participantes apresentaram diferenças nos acertos, a depender da valência positiva e negativa, sendo que 66,66% apresentaram diferenças para o tempo de resposta a depender da valência emocional. Após o procedimento de ensino, os participantes mostraram maior número de acertos nas tarefas, independentemente do gênero de estímulo e valência emocional, criando ocasião para generalização da aprendizagem de reconhecimento e nomeação de emoções, além de consolidar a viabilidade de estratégias de ensino mediadas por recursos tecnológicos e aplicadas por familiares.

Abstract: This study evaluated the recognition (imitation, identity, and identification) and naming of negative (anger and sadness) and positive (joy and surprise) emotional stimuli alongside the influence of the types of stimuli (social-female, social-male, family, and emoji) in children and young adults with autism and Down syndrome, via tasks applied by the family and mediated by technological resources, during the COVID-19 pandemic. Five children and two young adults with autism and one child and two young adults with Down syndrome participated. Identity, recognition, naming, and imitation tasks were planned and implemented using facial stimuli with evaluative (without differential consequence) and teaching (with differential consequence, tips, and learning criteria) functions, aiming at the emergence of emotional naming from the recognition teaching tasks. The baseline results showed that, for participants who had a shorter response time for the same gender, the response time difference was on average 57.28% lower. Regarding the emotional valence, 50% of the participants showed differences in the correct answers, depending on the positive and negative valence, and 66.66% showed differences in the response time depending on the emotional valence. After the teaching procedure, the participants showed a greater number of correct answers in the tasks, regardless of the stimulus type and emotional valence, creating an opportunity for generalizing learning of emotion recognition and naming, in addition to consolidating the feasibility of teaching strategies mediated by technological resources and applied by family members.

Resumen: Este estudio evaluó el reconocimiento (imitación, identidad e identificación) y la denominación de estímulos emocionales negativos (enfado y tristeza) y positivos (alegría y sorpresa) y la influencia de los tipos de estímulos utilizados (social-femenino, social-masculino, familiar y emoji ) de niños y jóvenes con autismo o síndrome de Down, a través de tareas aplicadas por la familia, mediadas por recursos tecnológicos durante la pandemia de la covid-19. Participaron cinco niños y dos adultos jóvenes con autismo, y un niño y dos adultos jóvenes con síndrome de Down. Se planificaron e implementaron tareas de identidad, reconocimiento, nombramiento e imitación con estímulos faciales con función evaluativa (sin consecuencia diferencial) y enseñanza (con consecuencia diferencial, uso de ayudas y criterios de aprendizaje), buscando la emergencia del nombramiento emocional después de la enseñanza de tareas de reconocimiento. Los resultados de la línea de base identificaron que para los participantes que tenían un tiempo de respuesta más corto para el mismo género, la diferencia en el tiempo de respuesta fue un 57,28% menor. En cuanto a la valencia emocional, el 50% de los participantes mostraron diferencias en las respuestas correctas, en función de la valencia positiva y negativa, y el 66,66% tuvieron diferencias en el tiempo de respuesta, en función de la valencia emocional. Después del procedimiento de enseñanza, los participantes mostraron mayor número de aciertos en las tareas evaluadas, independientemente del tipo de estímulo o valencia emocional, lo que genera una oportunidad para la generalización del aprendizaje de reconocimiento y denominación de emociones, además de consolidar la viabilidad de estrategias de enseñanza mediadas por recursos tecnológicos y aplicadas por la familia.

Formação em análise do comportamento no contexto da educação especial: variáveis pessoais e atitudinais relacionadas à inclusão / Training in behavior analysis in the context of special education: personal and attitudinal variables related to inclusion / Formación en análisis de conducta en el contexto de la educación especial: variables personales y actitudinales relacionadas con la inclusión

A inclusão educacional de estudantes com autismo e/ou deficiência intelectual no ensino regular, em classe comum, evidencia a urgência de programas de formação docente em práticas educacionais baseadas em evidências. O objetivo foi avaliar a estrutura de um processo formativo remoto para elaboração, aplicação e avaliação de uma intervenção comportamental na perspectiva educacional inclusiva e, mais especificamente, caracterizar as atitudes sociais de agentes educacionais participantes da formação. A formação ocorreu em dois formatos. No primeiro, todo o material foi disponibilizado em uma pasta virtual compartilhada e, no segundo, em um Ambiente Virtual de Aprendizagem (AVA). Nos dois formatos, a estrutura contou com parte teórica e prática, por meio de leitura de textos, realização de exercícios e discussões. Na parte prática, participantes tiveram a oportunidade de trabalhar com famílias e estudantes (crianças e jovens) com autismo e/ou deficiência intelectual visando identificar as necessidades e prioridades da família para elaboração colaborativa de um plano de intervenção (sistematização de práticas), implementação e análise das práticas. Para a caracterização da amostra foram levantadas informações pessoais, experiências prévias, familiaridade com ferramentas tecnológicas, conhecimento sobre os conceitos teóricos da Análise do Comportamento. Foi feita uma caracterização das atitudes sociais em relação à inclusão e analisada a validade social de participantes sobre a formação. Os resultados da formação identificaram correlações entre o nível de atitudes sociais e o engajamento nas atividades práticas entregues, além da relação entre o número de participantes que concluíram a formação, o cumprimento de tarefas e dificuldades de contato com a família. O estudo discutiu sobre estratégias que tenham em vista possibilidades de escalabilidade da formação docente de maneira sistemática e científica nesta área de atuação profissional.(AU)

The educational inclusion of students with autism and/or intellectual disabilities in regular education has highlighted the urgency of initial and continuing education programs with evidence-based educational practices. The objective was to evaluate the structure of a remote training process for the elaboration, application and evaluation of a behavioral intervention in the inclusive educational perspective and, complementarily, a specific objective was to characterize the social attitudes of educational agents participating in the training. The training took place in two formats. In the first, all material was made available in a shared folder and in the second, in a Virtual Learning Environment (VLE). In both formats, the structure had a theoretical and practical part, by reading and carrying out exercises and discussions. In the practical part, participants had the opportunity to work with families and students with autism and/or intellectual disability to identify the needs and priorities of the family for the collaborative elaboration of an intervention plan (systematization of practices), implementation and analysis of practices. For the characterization of the sample, personal information, previous experiences, familiarity with technological tools, and knowledge about the theoretical concepts of Behavior Analysis were collected. A characterization of social attitudes towards inclusion was carried out and the social validity of participants regarding training was analyzed. The results of the training identified correlations between the level of social attitudes and engagement in the practical activities delivered, in addition to the relationship between the drop in the number of participants, the fulfillment of tasks and difficulties in contacting the family. The study discussed strategies that aim at possibilities of scaling continuing education in a systematic and scientific way in this area of professional activity.(AU)

La inclusión educativa de estudiantes con autismo y/o discapacidad intelectual en la educación regular, en aulas regulares, ha puesto de relieve la urgencia de programas de educación inicial y continua en prácticas educativas basadas en evidencia. El objetivo de este estudio fue evaluar la estructura de un proceso de formación a distancia para la elaboración, aplicación y evaluación de una intervención conductual en la perspectiva educativa inclusiva y, de forma complementaria, el objetivo específico fue caracterizar las actitudes sociales de los agentes educativos participantes en la formación. La capacitación se llevó a cabo en dos formatos. En el primer, todo el material estaba disponible en una carpeta compartida y, en el segundo, en un entorno virtual de aprendizaje (EVA). En los dos formatos, la estructura tuvo una parte teórica y práctica, mediante la lectura de textos, la realización de ejercicios y discusiones. En la parte práctica, los participantes tuvieron la oportunidad de trabajar con las familias y los alumnos con autismo y/o discapacidad intelectual con el fin de identificar las necesidades y prioridades de la familia para la elaboración colaborativa de un plan de intervención (sistematización de prácticas), su implementación y el análisis de prácticas. Para la caracterización de la muestra, se planteó información personal, experiencias previas, familiaridad con herramientas tecnológicas, conocimiento sobre los conceptos teóricos del análisis de comportamiento. Se realizó una caracterización de las actitudes sociales hacia la inclusión y se analizó la validez social de los participantes respecto a la formación. Los resultados de la capacitación identificaron correlaciones entre el nivel de actitudes sociales y el compromiso en las actividades prácticas impartidas, además de la relación entre la disminución del número de participantes, el cumplimiento de las tareas y las dificultades de contacto con la familia. Este estudio discutió estrategias que apuntan a posibilidades de escalar la formación docente de forma sistemática y científica en esta área de actuación profesional.(AU)

Metabolomic approach for obstructive sleep apnea in adults: a systematic review.

Obstructive Sleep Apnea (OSA) corresponds to episodes of complete or partial upper airway obstruction during sleep. The gold standard for diagnosing OSA is polysomnography; however, metabolomics is an innovative and highly sensitive method that seeks to identify and quantify small molecules in biological systems. Identify the metabolites most frequently associated with obstructive sleep apnea in adults. The search for articles was conducted between October 2020 and August 2021, in electronic databases, such as MEDLINE/PubMed, Scielo, Embase, and Cochrane, through the combination of descriptors: obstructive sleep apnea, metabolomic, adult. This systematic review included all cross-sectional studies published, including human patients aged 18 years or older, of both genders who underwent type I or II polysomnography and metabolomics study. The search strategy selected 3697 surveys, and 4 of them were selected to be a part of this systematic review. Based on the analyzed surveys, it was found that all of them were able to diagnose OSA, reaching a sensitivity of 75-97%, and specificity that ranged from 72 to 100%; besides differentiating patients with OSA (severe, moderate, and mild) from simple snorers with a mean sensitivity of 77.2% and specificity of 66.25%. These findings suggest that, in addition to being used as a screening and diagnostic strategy for OSA, metabolomics has the potential to be used for severity stratification and to monitor the disease's progression.

Correction: Metabolomic approach for obstructive sleep apnea in adults: a systematic review.

[This corrects the article DOI: 10.1007/s41105-023-00445-5.].

Impact of L-carnitine in narcolepsy treatment: a systematic review on the effectiveness and safety.

Introduction: Studies have shown that narcolepsy patients may present with low serum acylcarnitine levels, demonstrating a dysfunctional beta fatty acid oxidation pathway in these patients. Objective: Evaluate the therapeutic efficacy of L-carnitine as a treatment for narcolepsy patients. Methods: This study runned in form of systematic review. The terms used for the search: ("narcolepsy"[MeSH Terms] OR "narcolepsy"[All Fields]) AND ("carnitine"[MeSH Terms] OR "carnitine"[All Fields] OR "l carnitine"[All Fields]). Were included all surveys published until January 2021, with the diagnosis of narcolepsy, that performed drug treatment with I-carnitine. The clinical endpoints of interest were: excessive daytime sleepiness, dissociative REM sleep manifestations: cataplexy, sleep paralysis, hypnagogic hallucinations, and early REM sleep (REM sleep naps, SOREMP). Results: L-carnitine was found to be well-tolerated and without side effects in all surveys, at dosages ranging from 500 to 510 mg/day. Newborns did not present complications during delivery. Conclusion: This study corroborates the efficacy and good tolerability of L-carnitine therapy as a treatment for patients with narcolepsy, including during pregnancy.

2H-1,2,3-Triazole-chalcones as novel cytotoxic agents against prostate cancer.

Prostate cancer is an important cause of death in the male population and for which there is no satisfactory chemotherapy. Herein a new series of chalcone hybrids containing 2H-1,2,3-triazole core as the ring B has been synthesized and evaluated in vitro against PC-3 prostate cancer cell line. Compounds 4a, 4c and 4e significantly reduced cell viability and showed IC50 of 28.55, 15.64 and 25.56 µM, respectively. The structure-activity relationship supported by computational chemistry points that the polarity of the molecular surface area should have some relevance to the efficiency of the compounds, in particular the ratio of the partial positive charge sites and the total molecular surface area exposed to the cell environment.

Crystal structure of 1-anilino-5-methyl-1H-1,2,3-triazole-4-carb-oxy-lic acid monohydrate.

In the mol-ecular structure of the title compound, C10H10N4O2·H2O, the angle between the triazole and arene rings is 87.39 (5)°. The water of crystallization connects the mol-ecules in the crystal packing. The crystal structure exhibits N-H⋯O, O-H⋯O and O-H⋯N inter-actions, resulting in the formation of a three-dimensional framework. The inter-molecular inter-actions were identified and qu-anti-fied using Hirshfeld surface analysis.

Study on the regioselectivity of the N-ethylation reaction of N-benzyl-4-oxo-1,4-dihydroquinoline-3-carboxamide.

4-Oxoquinolines are a class of organic substances of great importance in medicinal chemistry, due to their biological and synthetic versatility. N-1-Alkylated-4-oxoquinoline derivatives have been associated with different pharmacological activities such as antibacterial and antiviral. The presence of a carboxamide unit connected to carbon C-3 of the 4-oxoquinoline core has been associated with various biological activities. Experimentally, the N-ethylation reaction of N-benzyl-4-oxo-1,4-dihydroquinoline-3-carboxamide occurs at the nitrogen of the oxoquinoline group, in a regiosselective way. In this work, we employed DFT methods to investigate the regiosselective ethylation reaction of N-benzyl-4-oxo-1,4-dihydroquinoline-3-carboxamide, evaluating its acid/base behavior and possible reaction paths.

Aroylhydrazones constitute a promising class of 'metal-protein attenuating compounds' for the treatment of Alzheimer's disease: a proof-of-concept based on the study of the interactions between zinc(II) and pyridine-2-carboxaldehyde isonicotinoyl hydrazone.

With the increasing life expectancy of the world's population, neurodegenerative diseases, such as Alzheimer's disease (AD), will become a much more relevant public health issue. This fact, coupled with the lack of efficacy of the available treatments, has been driving research directed to the development of new drugs for this pathology. Metal-protein attenuating compounds (MPACs) constitute a promising class of agents with potential application on the treatment of neurodegenerative diseases, such as AD. Currently, most MPACs are based on 8-hydroxyquinoline. Recently, our research group has described the hybrid aroylhydrazone containing the 8-hydroxyquinoline group INHHQ as a promising MPAC. By studying the known structure-related ligand HPCIH, which does not contain the phenol moiety, as a simplified chemical model for INHHQ, we aimed to clarify the real impact of the aroylhydrazone group for the MPAC activity of a compound with potential anti-Alzheimer's activity. The present work describes a detailed solution and solid-state study of the coordination of HPCIH with Zn2+ ions, as well as its in vitro binding-ability towards this metal in the presence of the Aß(1-40) peptide. Similar to INHHQ, HPCIH is able to efficiently compete with Aß(1-40) for Zn2+ ions, performing as expected for an MPAC. The similarity between the behaviors of both ligands is remarkable. Taken together, the data presented herein point to aroylhydrazones, such as the compounds HPCIH and the previously published INHHQ, as encouraging MPACs for the treatment of AD.

New Polymorph Form of Dexamethasone Acetate.

A new monohydrated polymorph of dexamethasone acetate was crystallized and its crystal structure characterized. The different analytical techniques used for describing its structural and vibrational properties were: single crystal and polycrystal X-ray diffraction, solid state nuclear magnetic resonance, infrared spectroscopy. A Hirshfeld surface analysis was carried out through self-arrangement cemented by H-bonds observed in this new polymorph. This new polymorph form appeared because of self-arrangement via classical hydrogen bonds around the water molecule.

Pacientes com câncer de laringe no Nordeste: intervenção cirúrgica e reabilitação fonoaudiológica / Laryngeal cancer patients in the Northeast of Brazil: surgical intervention and speech rehabilitation

RESUMO Objetivo: caracterizar a assistência hospitalar em pacientes com câncer de laringe, na perspectiva da intervenção cirúrgica e reabilitação fonoaudiológica ofertada pelo Sistema Único de Saúde (SUS) na região Nordeste. Métodos: estudo epidemiológico descritivo, que contou com dados secundários obtidos via consulta à base de dados DATASUS, tendo levantado informações referentes ao período de janeiro de 2008 a dezembro de 2012. Resultados: aumento do número de casos de câncer de laringe com o passar dos anos, predominância do sexo masculino, aumento no número de internações, laringectomia parcial como procedimento médico mais utilizado e a maior quantidade de fonoaudiólogos vinculados ao SUS foi observada em Pernambuco. Conclusão: a assistência hospitalar aos pacientes com câncer de laringe contempla estratégias como procedimentos cirúrgicos e intervenção fonoaudiológica. Faz-se necessário que essa assistência contemple aspectos direcionados à prevenção de doenças, pois a informação em saúde, por meio de estratégias educativas, pode contribuir para o diagnóstico precoce e tratamento da doença.

ABSTRACT Purpose: to describe the hospital care provided to patients with laryngeal cancer in the Northeast of Brazil and the possibilities of surgical intervention and speech rehabilitation funded by Brazil's unified health system (SUS). Methods: this is a descriptive epidemiological study, which relied on secondary data obtained by searching the DATASUS database for information referring to the period between January 2008 and December 2012. Results: the study showed an increase in the number of cases of laryngeal cancer over the years, a predominance of male patients, and a larger number of hospitalizations; it also evidenced that the partial laryngectomy is the most frequent medical procedure, and that the state of Pernambuco has the largest number of speech therapists associated with the SUS. Conclusion: the provision of hospital care to patients with laryngeal cancer contemplates strategies such as surgical procedures and speech rehabilitation. This care should include aspects associated with disease prevention, as health information conveyed by means of educational programs may contribute to the early diagnosis and treatment of the illness.

Preferência de lado mastigatório e simetria facial em laringectomizados totais: estudo clínico e eletromiográfico / Preference side masticatory and facial symmetry in total laryngectomy: clinical and electromyographic study

OBJETIVO: observar se existe relação entre a preferência do lado mastigatório, antropometria facial e atividade elétrica do músculo masseter em laringectomizados totais. MÉTODOS: a coleta de dados, realizada no setor de Fonoaudiologia do Hospital de Câncer de Pernambuco (HCP), contou com a participação de quinze voluntários laringectomizados totais do gênero masculino e idade média de 64 anos. Foi realizada aferição das distâncias entre os pontos antropométricos faciais ex e ch nas hemifaces dos voluntários e posteriormente executado exame eletromiográfico dos músculos masseteres, bilateralmente, nos momentos de máxima intercuspidação habitual (MIH), mastigações unilaterais direita e esquerda e durante mastigação habitual. Realizou-se filmagem durante a mastigação habitual para identificação do lado de preferência mastigatória. RESULTADOS: os indivíduos cuja preferência mastigatória foi do lado direito, apresentaram o lado esquerdo da face com maior medida (72,37mm); já os indivíduos cuja preferência mastigatória foi do lado esquerdo, apresentaram maior medida da face do lado direito (68,85mm). Quando a mastigação apresentou-se unilateral direita a atividade elétrica do masseter direito atingiu média de 123,57% enquanto o masseter esquerdo alcançou média igual a 84,85% de atividade em relação à MIH (p = 0,016). CONCLUSÃO: em laringectomizados as medidas antropométricas faciais correlacionam-se com o lado de preferência de mastigação e os valores eletromiográficos dos masseteres durante a mastigação.

PURPOSE: to observe whether a relationship exists between the preference of chewing side, facial anthropometry and electrical activity of masseter muscle in total laryngectomy. METHODS: data collection, performed in the Speech Therapy Cancer Hospital of Pernambuco (HCP), with the participation of fifteen volunteers laryngectomized males and mean age of 64 years. We performed measurement of distances between points and anthropometric facial ex ch in hemifaces of volunteers and later executed EMG of the masseter muscles, bilaterally, in his habitual intercuspal (MHI), unilateral right and left chewing and during mastication. Filming took place during mastication to identify the side of the preference side. RESULTS: individuals whose right side is the masticatory predominance showed of the left side of the face to a greater extent (72.37 mm), while those whose prevalence of side left masticatory had higher estensão the side right (68.85 mm). In unilateral chewing right the electrical activity of the right masseter had an average 123.57% , while the left masseter showed an average 84.85% of the activity in relation to MHI (p = 0.016). CONCLUSION: in laryngectomized anthropometric facial measurements correlate with the preference side chewing and the values of the masseter EMG during mastication.

Responder de cães por exclusão em tarefas de discriminação condicional / Conditional discrimination responding by exclusion in dogs

O presente estudo treinou o responder por exclusão em cães por meio do ensino de discriminações condicionais entre objetos e seus respectivos nomes ditados e avaliou empiricamente a influência neste desempenho de dicas sociais humanas (gestos direcionados aos estímulos) quando estas eram direcionadas ao estímulo contrário. Os dois animais demonstraram rápida aquisição de controle pelo estímulo novo, controle que se manteve mesmo com a inserção de dicas sociais contrárias ao estímulo ditado (instruir oralmente a seleção de S+, porém apontar para S-). Foi evidente a influência das dicas sociais contrárias quando os estímulos eram familiares, com ruptura do controle preestabelecido. Discute-se a relevância deste estudo na comparação de diferentes aspectos do ambiente no comportamento canino, e enfatiza-se a necessidade de incluir sondas de controle pela novidade, para pesquisas futuras (AU)

This study trained the responding by exclusion in dogs, based on a conditional discrimination between dictated names and objects, and empirically evaluated the influence in that performance of human social cues (gestures directed to stimuli) towards the opposite stimulus. As a result, both animals showed rapid acquisition of control by the new stimulus, a pattern that persisted even after the inclusion of conflicting social cues toward the wrong stimulus (orally instructing the selection of S+, but pointing to the S-). The influence of conflicting social cues when the stimuli involved were familiar is clear, a pattern showed by the disruption of pre-established control. We discuss the relevance of this study in the comparison of different aspects of the environment on the behavior of dogs, and the need to include control probes for novelty in future research is emphasized (AU)

Responder de cães por exclusão em tarefas de discriminação condicional / Conditional discrimination responding by exclusion in dogs

O presente estudo treinou o responder por exclusão em cães por meio do ensino de discriminações condicionais entre objetos e seus respectivos nomes ditados e avaliou empiricamente a influência neste desempenho de dicas sociais humanas (gestos direcionados aos estímulos) quando estas eram direcionadas ao estímulo contrário. Os dois animais demonstraram rápida aquisição de controle pelo estímulo novo, controle que se manteve mesmo com a inserção de dicas sociais contrárias ao estímulo ditado (instruir oralmente a seleção de S+, porém apontar para S-). Foi evidente a influência das dicas sociais contrárias quando os estímulos eram familiares, com ruptura do controle preestabelecido. Discute-se a relevância deste estudo na comparação de diferentes aspectos do ambiente no comportamento canino, e enfatiza-se a necessidade de incluir sondas de controle pela novidade, para pesquisas futuras

This study trained the responding by exclusion in dogs, based on a conditional discrimination between dictated names and objects, and empirically evaluated the influence in that performance of human social cues (gestures directed to stimuli) towards the opposite stimulus. As a result, both animals showed rapid acquisition of control by the new stimulus, a pattern that persisted even after the inclusion of conflicting social cues toward the wrong stimulus (orally instructing the selection of S+, but pointing to the S-). The influence of conflicting social cues when the stimuli involved were familiar is clear, a pattern showed by the disruption of pre-established control. We discuss the relevance of this study in the comparison of different aspects of the environment on the behavior of dogs, and the need to include control probes for novelty in future research is emphasized

Incomplete swallowing and retracted tongue maneuvers for electromyographic signal normalization of the extrinsic muscles of the larynx.

PURPOSE: To investigate which muscular maneuvers provide larger electric activity (EA) of the suprahyoid (SH) and infrahyoid (IH) muscles to be used as surface electromyography (SEMG) signal normalization reference. METHODS: The electrical potentials of the SH and IH muscles of 12 subjects were evaluated using six muscular maneuvers, involving the position of the tongue and effort. It was selected as maximum voluntary sustained activity maneuver, the one having the minor coefficient of variation and the smallest value for each muscle group. The EA signal was converted using the root mean square in microvolts. It was considered then the maximum signal of each maneuver as the difference between the mean of three measures and the resting potential. RESULTS: The maneuvers that provided higher mean potentials with minor coefficient of variation and smallest P value were incomplete swallowing (IS) with effort (mean potential equal to 56.73±8.68 with coefficient of variation of 15.30%) in SH group, and tongue retracted with mouth open (TROM, mean potential equal to 46.57±7.83 with coefficient of variation of 16.81%) in IH group. CONCLUSION: The IS with effort and TROM maneuvers should be considered for signal normalization in these muscles, respectively, and may provide conditions for using the SEMG in voice clinic. SIGNIFICANCE: The use of normalization standards in researches of SH and IH muscles in the voice area will allow comparisons among future works.

Análise funcional de comportamentos inadequados e inclusão: uma contribuição à formação de educadores / Functional analysis of improper behavior and inclusion: a contribution to qualify the teachers´s work

Análises prévias da interação de uma criança com Síndrome de Down e seus pares em uma creche indicaram dois grandes problemas: pouca aceitação pelos colegas e mediação falha das educadoras na interação entre as crianças. O presente estudo implementou e avaliou um programa de intervenção baseado na análise funcional do comportamento para proporcionar formação para os educadores solucionarem tais problemas, lidando com comportamentos desafiadores exibidos pela criança, mediando sua interação com os colegas e otimizando sua escolarização como um todo. A intervenção foi baseada na consultoria colaborativa e consistiu em discussões com os educadores acerca da identificação das funções comportamentais dos comportamentos-problema para delineamento de estratégias para solucioná-los. Ao final do programa, observaram-se salientes mudanças comportamentais exibidas tanto pela criança com deficiência, quanto pelas educadoras, com diminuição significativa dos comportamentos inadequados identificados pela análise funcional (agressivos e disruptivos), bem como aumento de intervenções efetivas, de acordo com a função comportamental.(AU)

Previous analysis of the interaction patterns among a Down Syndrome child and peers in a regular school identified two major problems: fewer acceptance by other children, and flaw mediation of interaction among children. The present research designed, implemented and evaluated an intervention program for this classroom, based on functional analysis procedures, so the teachers could solve these problems, dealing with the child challenging behaviors, mediating interaction and improving the inclusion process in their class. The intervention was based on the co-operative consultancy and consisted on discussions with educators about problems found by using functional analysis and designed strategies to solve them, based on their behavioral function. At the end of the program, child and teacher achieved important behavioral changes. These may be concluded by the expressive decrease of both classes of problem behavior defined as intervention targets (Heteroagressive and Disruptive Behaviors), and also by the expressive growth of effective interventions according to behavior function.(AU)