ABSTRACT
OBJECTIVE: This randomized controlled clinical trial aimed to evaluate the effect of the casein phosphopeptide-amorphous calcium phosphate fluoride (CPP-ACPF) and photobiomodulation (PBM) in the treatment of dentin hypersensitivity (DH), and the impact of this on the health-related quality of life (HRQL). METHODS: Eighty teeth with DH were randomized into four groups and received three treatment sessions: PLACEBO = placebo + LASER application mimicking; CPP-ACPF = CPP-ACPF + LASER application mimicking; PBM = placebo + LASER active application; CPP-ACPF+PBM = CPP-ACPF + LASER active application. Tactile (exploratory probe) and evaporative (triple syringe) stimuli were used to measure DH and were recorded with the aid of a visual analogue scale (VAS) after the 1st, 2nd and 3rd treatment sessions and one-month follow-up. The HRQL was recorded in the DH experience questionnaire (DHEQ). RESULTS: The intragroup comparison showed a significant reduction in DH (p < 0.05) with both stimuli after one-month follow-up. The intergroup comparison with the evaporative stimulus showed that CPP-ACPF+PBM significantly reduced DH when compared to the rest of treatments, after one-month follow-up. CPP-ACPF+PBM group statistically differed from the other treatment groups in the DHEQ evaluation after one-month follow-up. CONCLUSION: After one-month follow-up, the association of CPP-ACPF with PBM was effective in the reduction of DH and promoted a positive impact on the HRQL of the participants of this study.
Subject(s)
Cariostatic Agents/administration & dosage , Caseins/administration & dosage , Dentin Sensitivity/therapy , Fluorides, Topical/administration & dosage , Low-Level Light Therapy/methods , Adolescent , Adult , Combined Modality Therapy/methods , Dentin Sensitivity/complications , Dentin Sensitivity/diagnosis , Drug Combinations , Female , Follow-Up Studies , Humans , Male , Middle Aged , Pain Measurement , Placebos/administration & dosage , Quality of Life , Treatment Outcome , Young AdultABSTRACT
CONTEXT: Remineralizing agents have been recommended to restore the integrity of bleached enamel. AIMS: The aim of this study was to evaluate the effect of fluoride at high concentration (5000 ppm) applied to bleached enamel. MATERIALS AND METHODS: A total of 30 specimens obtained from newly extracted third molars were divided into two groups (n = 15) as follows: control group and fluoride group. Specimens of both groups received bleaching treatment with 35% hydrogen peroxide, were then submitted to the Vickers hardness number/colorimetric test (VHN/CT) (n = 5) and Ra (n = 10) tests, and stored in artificial saliva. After bleaching, fluoride group received the application of a fluoride-based dentifrice, during 5 min. VHN, RS, and CT analysis of both groups were performed before and after treatments. For VHN, five indentations per specimen were performed, using a microdurometer. Ra analysis was performed with a rugosimeter. The color was analyzed through the CIE L* a* b* system, respectively, using a colorimeter. STATISTICAL ANALYSIS: For intergroup statistical analysis, ANOVA with Tukey's posttest was used. All tests were calculated at a significance level of 5%. RESULTS: There was statistically significant difference (P < 0.01) between the analyzed groups, on VHN, Ra, and CT evaluations. CONCLUSIONS: The use of fluoride-based dentifrice at 5000 ppm was effective in minimizing the deleterious effects on bleached enamel.
