ABSTRACT
The work is devoted to studying a possibility to use, for cytological diagnostics of urogenital neoplasms, of macrosystemic approaches, aimed to estimate cell systemic reactions during blasttransformation and treatment (exemplified by 95 urinary bladder cancer patients). Changes in size of nuclear and cytoplasmic areas were studied, in addition to the average activity of synthetic processes or functional activity of cell structures, and to the level of heterogeneity of functional tension in the cell space.
Subject(s)
Urinary Bladder Neoplasms/pathology , Aged , Dose Fractionation, Radiation , Electronic Data Processing , Female , Humans , Male , Middle Aged , Urinary Bladder Neoplasms/radiotherapy , Urothelium/pathology , Urothelium/radiation effectsABSTRACT
Correlations between immunologic indexes in patients suffering dyshormonal hyperplasia (33), carcinoma of the breast (48) and healthy females (25) were studied. Rosette-formation test and its modifications were used to evaluate immunologic vigor. No significant differences were found between the quantitative and structural characteristics of immunologic vigor. General relationship between correlations involved in dyshormonal hyperplasia and cancer of the breast were identified. Increased frequency of correlations between paired characteristics was reliably established in patients as compared with healthy subjects; also multiple correlations between the indexes of different lymphoid subpopulations were increased.
