1.
Clin Exp Dermatol
; 36(3): 307-9, 2011 Apr.
Article
in English
| MEDLINE
| ID: mdl-20846356
Subject(s)
Keratosis/complications , Melanoma/complications , Skin Neoplasms/complications , Aged , Humans , Male
2.
Hautarzt
; 62(1): 40-5, 2011 Jan.
Article
in German
| MEDLINE
| ID: mdl-20664992
ABSTRACT
Lichen planus is a chronic mucocutaneous T-cell-mediated disease, whose cause is still unknown. The first case of lichen planus that transformed into squamous cell carcinoma was reported in 1903. We present three patients in whom squamous cell carcinomas were identified in chronic lichen planus. The world literature includes at least 91 cases, including our three cases. In an epidemiological study, no significant risk of transformation of cutaneous lichen planus into squamous cell carcinomas was found. In contrast, there is a significantly higher risk of malignant transformation in mucosal lichen planus, so that the WHO had graded mucosal lichen planus as a premalignant condition.