Effects of acute exercise on emotional memory.

Research has demonstrated beneficial effects of acute exercise on memory for neutral materials, such as word lists of neutral valence/low arousal. However, the impacts of exercise on emotional memory is less understood. Across three laboratory experiments in college students, we tested if acute exercise could enhance both neutral and emotional memory performance, anticipating a greater effect for emotional memory. We examined effects of exercise at varying intensities (Experiment 1: high-intensity; Experiment 2: low- and high-intensity; Experiment 3: moderate-intensity), of diverse modalities (Experiment 1: treadmill jogging; Experiment 2: cycling; Experiment 3: open-skill (racquetball) and closed-skill (treadmill jogging) exercise), and on emotional memory performance assessed at increasing levels of hippocampal dependency (Experiment 1: Y/N recognition task; Experiment 2: paired-associative recognition task; Experiment 3: cued-recall task). We found that, in all experiments, acute exercise did not significantly influence emotional or neutral memory performance relative to sedentary control conditions. However, we observed several noteworthy outcomes indicating that acute exercise may be linked to improvements in memory confidence and accuracy for central aspects of emotional memory stimuli, and that select exercise modalities (e.g. treadmill exercise) may also be associated with increased frequency of memory intrusions.

Effects of Verbal Priming With Acute Exercise on Convergent Creativity.

The acute effects of moderate-intensity treadmill exercise during anagram problem solving on subsequent creativity performance has yet to be empirically investigated, which was this study's purpose. A two-visit (counterbalanced order), within-subject experiment was conducted among individuals aged 18-35. For the acute exercise visit, participants engaged in a 15-minute bout of moderate-intensity treadmill exercise while solving anagram problems. For the anagram only visit, participants engaged in 15 minutes of seated rest while solving anagram problems. Average RAT performance was higher for the exercise + anagram problem-solving visit (M = 10.51, SD = 3.25) compared to anagram-solving + seated rest (M = 9.29, SD = 4.12). The difference between conditions was statistically significant, t(44) = 2.385, p = .021, Cohen's d = 0.36. These findings demonstrate that acute exercise coupled with anagram problem-solving, prior to RAT completion, is a potential strategy for enhancing verbal convergent creative thinking.

Acute exercise and cognition: A review with testable questions for future research into cognitive enhancement with blood flow restriction.

Blood flow restriction, in combination with low load/intensity exercise, has consistently been shown to increase both muscle size and strength. In contrast, the effects of blood flow restricted exercise on cognition have not been well studied. Therefore, the purpose of this paper is 1) to review the currently available literature investigating the impact of blood flow restricted exercise on cognition and 2) to provide some hypotheses for how blood flow restriction might provide an additive stimulus for augmenting specific cognitive domains above exercise alone. Given the lack of research in this area, the effects of blood flow restricted exercise on cognition are still unclear. We hypothesize that blood flow restricted exercise could potentially enhance several cognitive domains (such as attention, executive functioning, and memory) through increases in lactate production, catecholamine concentration, and PGC-1α expression. We review work that suggests that blood flow restriction is not only a beneficial strategy to improve musculoskeletal function but could also be a favorable method for enhancing multiple domains of cognition. Nonetheless, it must be emphasized this is a hypothesis that currently has only minimal experimental support, and further investigations in the future are necessary to test the hypothesis.

Intelligence and creativity share a common cognitive and neural basis.

Are intelligence and creativity distinct abilities, or do they rely on the same cognitive and neural systems? We sought to quantify the extent to which intelligence and creative cognition overlap in brain and behavior by combining machine learning of fMRI data and latent variable modeling of cognitive ability data in a sample of young adults (N = 186) who completed a battery of intelligence and creative thinking tasks. The study had 3 analytic goals: (a) to assess contributions of specific facets of intelligence (e.g., fluid and crystallized intelligence) and general intelligence to creative ability (i.e., divergent thinking originality), (b) to model whole-brain functional connectivity networks that predict intelligence facets and creative ability, and (c) to quantify the degree to which these predictive networks overlap in the brain. Using structural equation modeling, we found moderate to large correlations between intelligence facets and creative ability, as well as a large correlation between general intelligence and creative ability (r = .63). Using connectome-based predictive modeling, we found that functional brain networks that predict intelligence facets overlap to varying degrees with a network that predicts creative ability, particularly within the prefrontal cortex of the executive control network. Notably, a network that predicted general intelligence shared 46% of its functional connections with a network that predicted creative ability-including connections linking executive control and salience/ventral attention networks-suggesting that intelligence and creative thinking rely on similar neural and cognitive systems. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

A Perspective on Implementing Movement Sonification to Influence Movement (and Eventually Cognitive) Creativity.

Creativity represents an important feature in a variety of daily-life and domain-specific contexts. Recent evidence indicates that physical movement serves as a key resource for exploring and generating task-relevant creative ideas, supporting the embodied perspective on creative cognition. An intuitive link between movement and creative cognition is movement creativity. The process of exploring the movement solutions an environment offers (i.e., affordances) and exploiting novel, functional, and creative movements may translate to and improve how individuals explore and generate novel ideas. Opening perception to the variety of affordances ("conventional" and novel) an environment offers drives creative movement. Teachers and coaches can promote this process by designing a learning environment that invites performers to consider and utilize novel movement solutions. In this article, we present a rationale for using movement sonification to promote creative movement. Movement sonification consists of mapping a movement parameter into sound, with a sound being triggered or changing according to how movement unfolds. We argue that movement sonification can facilitate the emergence of creative movement via enhancing perception of currently performed movements and invite performers to utilize novel affordances, and emphasizing information for regulating subsequent creative actions. We exemplify this concept in a creative dance intervention for children during physical education classes. In conclusion, we contend that learning to explore original dance sequences using movement sonification may provide a meaningful link between creative movement and creative cognition. Children may use their minds and bodies as tools for creative thinking and exploration, such as shaping letters with their bodies.

The Effects of Acute Exercise on Retroactive Memory Interference.

PURPOSE: Retroactive interference involves the disruption of previously encoded information from newly learned information and thus may impair the consolidation of long-term memory. The objective of this study was to evaluate whether acute exercise can attenuate retroactive memory interference. DESIGN: Three experimental studies were employed. Experiment 1 employed a between-subject randomized control trial (RCT) involving moderate-intensity walking (15 minutes). Experiment 2 employed a between-subject RCT involving high-intensity jogging (15 minutes). Experiment 3 employed a within-subject RCT involving moderate-intensity walking (15 minutes). SETTING: University setting. PARTICIPANTS: One hundred twelve young adults. MEASURES: After exercise, memory interference was evaluated from an episodic word-list memory task, involving the recall of 2 word lists. RESULTS: The pooled effect size (standard difference in means: -0.35; 95% confidence interval: -0.64 to -0.06) across the 3 experiments was statistically significant (P = .01). CONCLUSION: We provide suggestive evidence that acute, short-duration exercise may help attenuate a retroactive memory interference effect. Implications of these findings for exercise to improve memory and attenuate memory decay are discussed.

Acute Exercise, Psychological Stress Induction, and Episodic Memory.

Objective: In this study, we evaluated whether exercise prior to memory encoding or during memory consolidation can influence episodic memory function after being exposed to a stressful environment. Methods: We conducted 3 between-group randomized controlled experiments among young adults. We assessed episodic memory (via logic memory task) at the beginning of the experiment and approximately 45 minutes later. Across the 3 experiments, we varied the temporal period (eg, before memory encoding or during consolidation) of the acute bout of exercise (15-minute moderate-intensity exercise) and psychological stress induction. Results: Across all 3 experiments there was a statistically significant main effect for time for memory function, but there were no time x group interaction effects. Conclusion: Memory declined across the 2 assessment periods, but for all 3 experiments, exercise was not associated with memory function after being exposed to a stressful stimulus.

Role of Embodied Movement in Assessing Creative Behavior in Early Childhood: A Focused Review.

The controlled measurement of creative potential in early childhood is imperative for researchers seeking to fully understand the initial emergence and development of creativity. Evidence for original ideation has been demonstrated in infants as young as one year old, through their performance of movement-based, interactive creativity tasks. In this focused review of developmental research, we suggest that embodied movements and interactive play may uniquely facilitate creative thinking in early childhood (i.e., from birth to age six). From this review, we propose that embodied movement reinforces physical interactions that influence cognitions underlying creative behavior. Embodied creativity may supplement traditional creativity measures, as young children may be more inclined to represent their inner thoughts and experiences through movement rather than through language alone. Thus, we explored the importance of embodied creativity as a means of informing current researchers about the development of creativity, and we suggest future experimental research in this area.

Association Between Motor Skills and Musculoskeletal Physical Fitness Among Preschoolers.

OBJECTIVE: Previous work is conflicted regarding the relationship between motor skill development and physical activity. One potential explanation for this equivocality is the difficulty and lack of precision in physical activity measurement, particularly within preschool populations. Our exploration of plank performance as a proxy measure for fitness addresses a void in the literature, as few studies have investigated the role of motor skill development on fitness. The purpose of this study was to evaluate the potential relationship between motor skill level and musculoskeletal endurance (via the plank test). METHODS: Data from the 2012 National Youth Fitness Survey were used, which included 224 preschool-aged children (3-5 years). Motor skill level was assessed from the Test of Gross Motor Development-Second Edition (TGMD2). Motor skill parameters included general motor skills, locomotor skills, and object control skills. RESULTS: Within this nationally representative sample of preschoolers, increased motor skills were positively associated with plank performance [General Motor Skills (ß = 0.45; 95% CI 0.31-0.59), locomotor skills (ß = 1.88; 95% CI 1.15-2.61), and object control skills (ß = 2.05; 95% CI 1.11-2.98)]. CONCLUSION: Motor skill level in this national preschool sample was associated with musculoskeletal endurance. Thus, future interventions should aim to develop and refine motor skills among preschoolers.

Physical Activity, Muscle-Strengthening Activities, and Systemic Inflammation Among Retinopathy Patients.

OBJECTIVE: We evaluated the specific association between muscle-strengthening activity (MSA) and accelerometer-assessed physical activity on systemic inflammation among retinopathy patients in the United States. METHODS: Data from the 2005-2006 National Health and Nutrition Examination Survey (NHANES) were used to identify 157 retinopathy patients between 40 and 85 years of age with complete data on select study variables. MSA was assessed via self-report. Participation in moderate-to-vigorous physical activity (MVPA) was determined from objective accelerometer data. Systemic inflammation was assessed using C-reactive protein (CRP), which was quantified using latex-enhanced nephelometry. Nonproliferative retinopathy was determined using Early Treatment Diabetic Retinopathy Study grading criteria, as well as objective retinal imaging assessments using the Canon Non-Mydriatic Retinal Camera CR6-45NM. Individuals were excluded if they had been diagnosed with coronary artery disease, congestive heart failure, heart attack, or stroke. RESULTS: MVPA (ß = -0.004, 95% CI -0.007 to -0.001, P = 0.006) but not MSA (ß = -0.0001, 95% CI -0.002 to 0.001, P = 0.86) was associated with lower CRP levels. Additionally, for a more substantive 30 minutes/day increase in MVPA, there was a corresponding 0.12 mg/dL decrease in CRP. CONCLUSION: In this nationally representative sample of adults, only individuals who engaged in higher levels of MVPA had lower CRP levels, which is indicative of reduced systemic inflammation. MSA was not associated with systemic inflammation among this cohort. Our findings suggest that MVPA is inversely associated with systemic inflammation among retinopathy patients, which is noteworthy because increased systemic inflammation may facilitate retinopathic severity.

Association of Single and Multiple Medical Conditions with Work Status among Adults in the United States.

BACKGROUND: The purpose of this study was to comprehensively examine the association of a multitude of individual medical conditions, as well as multimorbidity, on work status among a national sample of U.S. adults. METHODS: The present study included 7 cycles (1999-2012) from the National Health and Nutrition Examination Survey (N = 28,119). RESULTS: In total, 26 medical conditions increased the odds of not working. Multimorbidity as well as having prevalent medical condition(s) within each of the Cumulative Index Rating Scale Morbidity Classes were associated with increased odds of not working. Few medical conditions were associated with higher odds of working part-time (vs. full-time) or unemployment (vs. working). CONCLUSION: These findings underscore the importance of instating comprehensive worksite wellness health promotion policies, as well as providing individuals with resources to preserve and enhance personal health.

Secular trends in the association between obesity and hypertension among adults in the United States, 1999-2014.

OBJECTIVE: To examine the secular trends in the association between obesity and hypertension among American adults between 1999 and 2014. METHODS: Data from the 1999-2014 National Health and Nutrition Examination Survey (eight survey cycles) were used. Obesity was determined from measured body mass index, with hypertension assessed from measured blood pressure and self-reported medication use. Meta-regression was used to examine the linear, quadratic, and cubic trends of the relationship between the observed odds ratio effect sizes (obesity and hypertension) and the NHANES cycles (year) using a random-effects model. RESULTS: Across the years of 1999 to 2014, there was a significant, positive linear trend (p = .006) in the association between overweight/obesity and hypertension. CONCLUSION: Our findings suggest that the association between overweight/obesity and hypertension is becoming stronger over time. Continued surveillance of temporal changes associated with obesity and hypertension is necessary to monitor how such changes may underlie changes in the risk for chronic disease. SIGNIFICANCE OF THE STUDY: This novel study evaluates whether the magnitude of association between obesity and hypertension has changed over the last 15-years.

Memory-Related Encoding-Specificity Paradigm: Experimental Application to the Exercise Domain.

The Encoding-Specificity Paradigm indicates that memory recall will be superior when contextual factors are congruent between memory encoding and memory retrieval. However, unlike other contextual conditions (e.g., verbal context, mental operations, global feature context, mood dependency, and physical operations), this paradigm has nearly been ignored in the exercise domain. Thus, the purpose of this study was to examine the Encoding-Specificity Paradigm in the context of exercise and rest conditions. 24 young adults (age: M = 21 years) completed a within-subject, counterbalanced experiment involving four laboratory visits, including 1) R-R (rest-rest) condition, 2) R-E (rest-exercise) condition, 3) E-R (exercise-rest) condition, or 4) E-E (exercise-exercise) condition. The exercise bout included a 15-minute moderate-intensity walk on a treadmill. Memory recall was assessed via a 15 word-list task. Memory recall was greater for R-R (8.71 ± 3.1) versus R-E (7.46 ± 2.8), and similarly, for E-E (8.63 ± 2.7) versus E-R (8.21 ± 2.7). The mean word recall for the congruent and incongruent conditions, respectively, was 8.67 (2.4) and 7.83 (2.4). There was a statistically significant condition effect (F = 5.02; P = .03; partial η² = .18). This experiment provides direct support for the Encoding-Specificity Paradigm in the exercise domain.

Systematic Review of the Proposed Associations between Physical Exercise and Creative Thinking.

The objective of this study was to evaluate the association between physical exercise and creative thinking. A systematic review approach was employed by searching PubMed, Google Scholar and PsychInfo databases. Among the evaluated 13 studies, 92% indicated a beneficial relationship. However, 77% were vulnerable to moderate-high risk for methodological bias, suggesting adherence to standardized and controlled research initiatives should be promoted. There appears to be weak to modest support for acute, moderate-intensity exercise to benefit creativity. Exercise timing relative to creativity assessment protocols should be addressed and further detailed. Creativity scoring procedures must be refined, and an increased focus on the motivational components of exercise may help guide researchers in measuring creative thoughts and behavior. Broader concluding claims that creativity, in general, is improved or impaired by exercise, is as problematic as sweeping statements that exercise improves or impairs a measure as dynamic as intelligence. Scientific inquiries must specify precisely which outcome characteristics are changing in line with research interventions. This review identifies several fallible linkages between physical activity and creativity. Too few studies were conducted on strong methodological foundations, perpetuating the risk for undermining or inaccurately inflating the potential association between exercise and creative thinking behavior.

Association Between Perceived Physical Activity and Cognitive Function in Older Adults.

There is irrefutable evidence that regular participation in physical activity is favorably associated with numerous positive health outcomes, including cognitive function. Emerging work suggests that perceived physical activity, independent of actual physical activity behavior, is inversely associated with mortality risk. In this study, we evaluate whether perceived physical activity, independent of actual physical activity, is associated with cognitive function, a robust indicator of mortality risk. Data from the cross-sectional 1999-2002 National Health and Nutrition Examination Survey were employed ( N = 2352; 60+ years of age). Actual physical activity was assessed via a validated survey. Perceived physical activity was assessed using the following question: "Compared with others of the same age, would you say that you are: more active, less active, or about the same?" Cognitive function was assessed from the Digit Symbol Substitution Test. When examined in separate models, both actual and perceived physical activity were positively and statistically significantly associated with cognitive function. However, when considered in the same model, actual physical activity was no longer statistically significantly associated with cognitive function, but perceived physical activity was. Perceived physical activity, independent of actual physical activity, is independently associated with cognitive function. If these findings are replicated, future work should consider evaluating perceived physical activity when examining the effects of actual physical activity behavior on cognitive function.

15-Year Secular Trends in Cognitive Function Among Older Adults in the United States.

Cognitive impairment is associated with various chronic diseases, including mobility limitation and early mortality. Thus, evaluating changes in cognition is of paramount public health interest. The purpose of this study was to evaluate secular trends in cognitive function among a representative sample of the U.S. older adult population. Data from the 1999-2000, 2001-2002, 2011-2012, and 2013-2014 National Health and Nutrition Examination Survey were utilized to identify an aggregate sample of adults 60+ years of age. The sample size across the four respective cycles was 1417, 1558, 1422, and 1592. Three cognitive assessments were employed, including the CERAD Word Learning subset (Consortium to Establish a Registry for Alzheimer's disease), the Animal Fluency test, and the Digit Symbol Substitution Test (DSST). For the entire sample and several subpopulations, DSST scores increased from 1999 to 2012 and then decreased in the 2013 to 2014 cycle. For all CERAD trials, there was evidence of increased CERAD performance from 2011-2012 to 2013-2014. No secular trends were observed for the Animal Fluency task across these cycles. Select cognitive parameters appear to be improving among U.S. older adults. Future work is needed to further explore secular trends in cognitive sustainability, and, as evidenced by our present study, cognitive enrichment over time.

A brief primer on the mediational role of BDNF in the exercise-memory link.

One of the most amazing aspects of the human brain is its ability to learn information and use it to change behaviour. A key neurotrophin that influences memory function is brain-derived neurotrophic factor (BDNF). This review briefly discusses the mechanistic role that BDNF may play in facilitating learning and memory. We also describe the role of exercise on this relationship. As discussed herein, BDNF may influence memory via BDNF-induced alterations in membrane receptor expression and translocation, as well as activating several pathways (PLC-y, PI3K, ERK) that act together to facilitate cellular effects that influence synaptic plasticity. Exercise may help to facilitate BDNF expression and its downstream cellular pathways from both direct and indirect mechanisms.

Protective and therapeutic effects of exercise on stress-induced memory impairment.

The objective of this paper was to systematically evaluate the potential preventive and therapeutic effects of exercise in attenuating stress-induced memory impairment. A systematic review was employed, searching PubMed, PsychInfo, Sports Discus and Google Scholar databases. For eligibility, studies had to be published in English, employ an experimental design, have the acute or chronic bout of exercise occur prior to, during or after the stressor, implement a psychophysiological stressor, and have an assessment of memory function occurring after the stressor. In total, 23 studies were evaluated, all of which were conducted among animal models. All 23 studies employed a chronic exercise protocol and a chronic stress protocol. Eight studies evaluated a preventive model, three employed a concurrent model, ten studies employed a therapeutic model, and two studies evaluated both a preventive and therapeutic model within the same study. Among the eight studies employing a preventive model, all eight demonstrated that the stress regimen impaired memory function. In all eight of these studies, when exercise occurred prior to the stressor, exercise attenuated the stress-induced memory impairment effect. Among the ten studies employing a therapeutic model, one study showed that the stress protocol enhanced memory function, one showed that the stress protocol did not influence memory, and eight demonstrated that the stress regimen impaired memory function. Among the eight studies showing that the stress protocol impaired memory function, all eight studies demonstrated that exercise, after the stressor, attenuated stress-induced memory impairment. Within animal models, chronic stress is associated with memory impairment and chronic exercise has both a preventive and therapeutic effect in attenuating stress-induced memory impairment. Additional experimental work in human studies is needed. Such work should also examine acute exercise and stress protocols.

Association of physical activity on the functional connectivity of the hippocampal-orbitofrontal pathway.

Objective: The objective of the study is to examine the association between physical activity and hippocampal-orbitofrontal functional connectivity. Methods: Data from the Nathan Kline Institute-Rockland Sample was utilized, which consisted of 366 participants (Mage = 43 years; 63% female). Physical activity was self-reported using the International Physical Activity Questionnaire. Hippocampal-orbitofrontal functional connectivity was assessed from magnetic resonance imaging. Results: Moderate-intensity physical activity was not statistically significantly associated with left hippocampal-orbitofrontal connectivity (ß = 0.001; 95% CI: -0.02, 0.03; P = 0.90) or right hippocampal-orbitofrontal connectivity (ß = 0.01; 95% CI: -0.01, 0.04; P = 0.22). However, vigorous-intensity physical activity was statistically significantly associated with right hippocampal-orbitofrontal connectivity (ß = 0.01; 95% CI: 0.004, 0.02; P = 0.002). Discussion: Habitual engagement in intense physical activity was associated with greater hippocampal-orbitofrontal connectivity, while moderate activity engagement was not. This may have important implications for the exercise neurobiology field in the context of exercise and memory function, suggesting that intense activity may facilitate cognitive/memory functions. However, our findings should be interpreted with caution given the relatively weak associations that were observed.

Experimental Effects of Acute Exercise on Episodic Memory Function: Considerations for the Timing of Exercise.

Our previous work employing a between-subject randomized controlled trial design suggests that exercising prior to memory encoding is more advantageous in enhancing retrospective episodic memory function when compared to exercise occurring during or after memory encoding. The present experiment evaluates this potential temporal effect of acute exercise on memory function while employing a within-subject, counterbalanced design. In a counterbalanced order (via Latin squares), 24 participants completed four visits including (1) exercising (moderate-intensity walking) prior to memory encoding, (2) exercising during memory encoding, (3) exercising after memory encoding, and (4) a control visit (no exercise). Retrospective memory function (short term and long term; 24-hour follow-up) was assessed from a multitrial word list. Prospective memory was assessed from a time-based task. Compared to all other visits, short-term memory was greater in the visit that involved exercising prior to memory encoding (F = 3.76; P = .01; η2 = .79). Similar results occurred for long-term memory, with no significant effects for prospective memory performance. We provide robust evidence demonstrating that acute moderate-intensity exercise prior to memory encoding is optimal in enhancing short-term and long-term memory function when compared to no exercise as well as exercising during and after memory encoding.