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Immunohistochemical expression of COX-2 and c-kit in metastatic uveal melanoma.
Frota, Ana C A; Odashiro, Alexandre N; Pereira, Patricia R; Fernandes, Bruno F; Godeiro, Katyanne Dantas; Filho, Joao Pessoa Souza; Burnier, Miguel N.
Can J Ophthalmol ; 42(1): 145-6, 2007 Feb.
Article in English | MEDLINE | ID: mdl-17361263

ABSTRACT

CASE REPORT: We report a case of choroidal melanoma metastatic to the liver diagnosed by fine-needle aspiration. The biopsy sample was immunostained for COX-2 and c-kit. COMMENTS: Accurate diagnosis and identification of potential therapeutic targets are important for subsequent therapy and can be achieved by radiologically guided fine-needle aspiration biopsy.


Subject(s)
Choroid Neoplasms/metabolism , Cyclooxygenase 2/metabolism , Liver Neoplasms/metabolism , Melanoma/metabolism , Proto-Oncogene Proteins c-kit/metabolism , Aged , Biopsy, Needle , Choroid Neoplasms/pathology , Humans , Immunohistochemistry , Liver Neoplasms/secondary , Male , Melanoma/secondary
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