ABSTRACT
A group of patients who developed postoperative shivering after receiving inhalational anaesthesia were assigned, at random, to receive either doxapram or a placebo under double-blind conditions. A significantly higher proportion of patients stopped shivering after being given doxapram than after the placebo.
Subject(s)
Anesthesia, Inhalation/adverse effects , Doxapram/therapeutic use , Postoperative Complications/drug therapy , Shivering/drug effects , Adolescent , Adult , Female , Humans , Male , Middle AgedABSTRACT
Glycopyrrolate is shown to reduce the incidence of large volumes (more than 40 ml) of postoperative gastric contents, but not the pH, after major abdominal operations and reduce the consequent risk of regurgitation. It should be preferred to atropine during these procedures.
Subject(s)
Abdomen/surgery , Glycopyrrolate/therapeutic use , Pneumonia, Aspiration/prevention & control , Pyrrolidines/therapeutic use , Adult , Atropine/therapeutic use , Clinical Trials as Topic , Gastric Juice/analysis , Humans , Hydrogen-Ion Concentration , Postoperative Complications/prevention & controlSubject(s)
Postoperative Complications/therapy , Vomiting/therapy , Adult , Female , Humans , Male , Pressure , WristABSTRACT
A technique of postoperative analgesia using continuous intravenous papaveretum with a dosage derived from previous intravenous titration is described. Hourly pain scores, pulse and respiration rates, and blood pressure readings were recorded. The patients were followed up until discharge from hospital. The nature and incidence of various complications were noted.
Subject(s)
Opium/administration & dosage , Pain, Postoperative/drug therapy , Adult , Aged , Female , Humans , Infusions, Parenteral , Male , Middle Aged , Opium/therapeutic useABSTRACT
Sublingual buprenorphine (0.4 mg) and intramuscular papaveretum (20 mg) were compared in sixty patients after abdominal hysterectomy. Though slower in onset of effect the sublingual tablets proved effective for pain relief and appeared to have a longer duration of action. The only side-effects of note were nausea and vomiting which occurred after both treatments. Haloperidol was tried as a long acting antiemetic and appeared successful.
Subject(s)
Buprenorphine/therapeutic use , Morphinans/therapeutic use , Pain, Postoperative/drug therapy , Papaverine/therapeutic use , Adult , Buprenorphine/adverse effects , Double-Blind Method , Evaluation Studies as Topic , Female , Humans , Kinetics , Papaverine/adverse effects , Random AllocationABSTRACT
The action of orphenadrine when given towards the end of a general anaesthetic is described. It is shown to delay the need for postoperative analgesia and extend the analgesic action of papaveretum.
Subject(s)
Analgesia , Opium , Orphenadrine , Pain, Postoperative/prevention & control , Clinical Trials as Topic , Drug Evaluation , Female , Humans , Middle Aged , Random Allocation , Time FactorsABSTRACT
A technique of general anaesthesia involving the use of propanidid, nitrous oxide, oxygen and halothane followed by a slow injection of suxamethonium and lignocaine is described. The technique decreased the increase in serum potassium concentration that follows the injection of suxamethonium and, it is suggested, possesses advantages over the existing practice of the injection of non-depolarizing neuromuscular blocking drugs before suxamethonium in an attempt to reduce the frequency of serious cardiac arrhythmia.
