1.
Chem Commun (Camb)
; 55(26): 3753-3756, 2019 Mar 26.
Article
in English
| MEDLINE
| ID: mdl-30860533
ABSTRACT
We present a DNA-encoded chemical library, which allows dynamic selection followed by ligation of the encoding strands. As a chemical approach to mimic the genetic recombination process of adaptive immunity, the technology led to an enhanced enrichment factor and signal-to-noise ratio compared to static libraries.