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1.
Article in English | MEDLINE | ID: mdl-38532635

ABSTRACT

PURPOSE: To analyze the dynamic response of the lumbosacral vertebrae structure of a scoliosis spine and a kyphosis spine under whole-body vibration. METHODS: Typical Lenke4 (kyphosis) and Lenke3 (scoliosis) spinal columns were used as research objects. A finite element model of the lumbosacral vertebrae segment was established and validated based on CT scanning images. Modal, harmonic response, and transient dynamic analyses were performed on the lumbar-sacral scoliosis model using the finite element software abaqus. RESULTS: The first four resonance frequencies of kyphosis spine extracted from modal analysis were 0.86, 1.45, 8.51, and 55.71 Hz. The first four resonance frequencies of scoliosis spine extracted from modal analysis were 0.76, 1.45, 10.51, and 63.82 Hz. The scoliosis spine had the maximum resonance amplitude in the transverse direction, while the kyphosis spine had the maximum resonance amplitude in the anteroposterior direction. The dynamic response in transient analysis exhibited periodic response over time at all levels. CONCLUSION: The scoliosis and kyphosis deformity of the spine significantly complicates the vibration response in the scoliosis and kyphosis areas at the top of the spine. Scoliosis and kyphosis patients are more likely to experience vibrational spinal diseases than healthy people. Besides, applying vertical cyclic loads on a malformed spine may cause further rotation of scoliosis and kyphosis deformities.

2.
Biomed Mater Eng ; 34(6): 525-535, 2023.
Article in English | MEDLINE | ID: mdl-37248875

ABSTRACT

BACKGROUND: Currently, quadrilateral anterior cervical plate (QACP) is a highly prevalent ACP. OBJECTIVE: This study aims to design a novel ACP using topology optimization (TOACP). METHODS: A completed model for C1-C7 cervical segments was established and validated. QACP and TOACP cage systems were implanted within two cervical vertebrae models, respectively, and peak stresses and stress distributions for screw, plate, endplate and cage displacement were investigated under differing exercise modes. RESULTS: Stress levels upon QACP screw were maximized for over-extension exercise (243.3 MPa, 3.35% > TOACP screw). Stress level upon TOACP plate was maximized for over-extension exercise (118.2 MPa, 7.26% > QACP screw). Following QACP cage system implantation, stress on endplate and cage displacement were maximized for extension exercise, which were 27.1%, and 6.3% > TOACP cage system, respectively. Finite element analysis results revealed that topological optimization of the plate can effectively reduce screw stress, thereby enhancing cervical segments' stability during surgery. Furthermore, stress on endplate and cage displacement decreased, indicating great potential in cage sinking and fusion enhancement. CONCLUSIONS: Topological optimization of the plate equips the cage system with advantages in clinical applications and biomechanical performance, providing alternative solutions and a theoretical basis for ACP design.


Subject(s)
Spinal Fusion , Biomechanical Phenomena , Spinal Fusion/methods , Range of Motion, Articular , Bone Plates , Bone Screws , Cervical Vertebrae/surgery , Finite Element Analysis
3.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi ; 40(2): 303-312, 2023 Apr 25.
Article in Chinese | MEDLINE | ID: mdl-37139762

ABSTRACT

To investigate the effects of postoperative fusion implantation on the mesoscopic biomechanical properties of vertebrae and bone tissue osteogenesis in idiopathic scoliosis, a macroscopic finite element model of the postoperative fusion device was developed, and a mesoscopic model of the bone unit was developed using the Saint Venant sub-model approach. To simulate human physiological conditions, the differences in biomechanical properties between macroscopic cortical bone and mesoscopic bone units under the same boundary conditions were studied, and the effects of fusion implantation on bone tissue growth at the mesoscopic scale were analyzed. The results showed that the stresses in the mesoscopic structure of the lumbar spine increased compared to the macroscopic structure, and the mesoscopic stress in this case is 2.606 to 5.958 times of the macroscopic stress; the stresses in the upper bone unit of the fusion device were greater than those in the lower part; the average stresses in the upper vertebral body end surfaces were ranked in the order of right, left, posterior and anterior; the stresses in the lower vertebral body were ranked in the order of left, posterior, right and anterior; and rotation was the condition with the greatest stress value in the bone unit. It is hypothesized that bone tissue osteogenesis is better on the upper face of the fusion than on the lower face, and that bone tissue growth rate on the upper face is in the order of right, left, posterior, and anterior; while on the lower face, it is in the order of left, posterior, right, and anterior; and that patients' constant rotational movements after surgery is conducive to bone growth. The results of the study may provide a theoretical basis for the design of surgical protocols and optimization of fusion devices for idiopathic scoliosis.


Subject(s)
Scoliosis , Spinal Fusion , Humans , Scoliosis/surgery , Spinal Fusion/methods , Lumbar Vertebrae/surgery , Osteogenesis , Biomechanical Phenomena/physiology , Finite Element Analysis
4.
Biomed Mater Eng ; 34(3): 225-234, 2023.
Article in English | MEDLINE | ID: mdl-36213985

ABSTRACT

BACKGROUND: Although the internal fixation technique for scoliosis is effective, there is a great risk of nail placement in actual operation. OBJECTIVE: To compare the effects of three different nail placement strategies on LenkeC patients with scoliosis under cyclic loading. METHODS: Firstly, the finite element model was established by using CT scanning images and X-ray images of patients with LenkeC scoliosis. Secondly, the validity of the model was verified. Finally, the harmonic response analysis and transient dynamic analysis were carried out. RESULTS: The results showed that the maximum amplitude of each vertebral body appeared in the Z direction at the third natural frequency and the amplitudes of each corresponding vertebral body were very close under three kinds of nail placement. Under different nail placement methods, the uneven distribution of nails would make the model produce obvious stress concentration, but the principal stress of vertebral body and nail rod was far lower than its own yield strength. This showed that under the axial cyclic load, the vertebral bodies of scoliosis tended to have larger impact in Z direction. From the point of view of dynamics, it was feasible to reduce a certain number of nails in operation. CONCLUSION: This paper revealed that it was feasible to reduce a certain number of nails during surgery.


Subject(s)
Scoliosis , Humans , Scoliosis/diagnostic imaging , Scoliosis/surgery , Nails , Fracture Fixation, Internal , Tomography, X-Ray Computed , Finite Element Analysis , Biomechanical Phenomena
5.
PLoS One ; 16(4): e0250270, 2021.
Article in English | MEDLINE | ID: mdl-33857243

ABSTRACT

The quadrilateral anterior cervical plate (ACP) is used extensively in anterior cervical discectomy and fusion (ACDF) to reconstruct the stability of the cervical spine and prevent cage subsidence. However, there have been no comparison studies on the biomechanical performance of quadrilateral ACP and triangular ACP. The objective of this study is to investigate the functional outcomes of quadrilateral ACP and triangular ACP usage in ACDF surgery. In this study, a finite element model of intact C1-C7 segments was established and verified. Additionally, two implant systems were built; one using triangle anterior cervical plates (TACP) and another using quadrilateral orion anterior cervical plate (QACP). Both models were then compared in terms of their postoperative biomechanical performance, under normal and excessive motion. Compared to QACP, the peak stress of the TACP screws and plates occurred at 359.2 MPa and 97.2 MPa respectively and were the highest during over extension exercises. Alternately, compared to TACP, the endplate peak stress and the cage displacement of QACP were the largest at over extension, with values of 7.5 MPa and 1.2 mm, respectively. Finally, the average stress ratio of bone grafts in TACP was relatively high at 31.6%. In terms of biomechanical performance, TACP can share the load more flexibly and reduce the risks of cage subsidence and slippage but the screws have high peak stress value, thereby increasing the risk of screw slippage and fracture. This disadvantage must be considered when designing a TACP based implant for a potential patient.


Subject(s)
Bone Plates , Bone Screws , Bone Transplantation/instrumentation , Cervical Vertebrae/surgery , Models, Anatomic , Spinal Fusion/methods , Biomechanical Phenomena , Cervical Vertebrae/diagnostic imaging , Diskectomy/methods , Finite Element Analysis , Humans , Intervertebral Disc/diagnostic imaging , Intervertebral Disc/surgery , Range of Motion, Articular/physiology , Spinal Fusion/instrumentation , Stress, Mechanical , Tomography, X-Ray Computed
6.
Biomed Mater Eng ; 24(6): 2381-8, 2014.
Article in English | MEDLINE | ID: mdl-25226938

ABSTRACT

This paper studies the effect of Uyghur sand therapy on dynamics of arterial flow of knee joints via experiments and numerical simulations. Experiments have been carried out on 30 volunteers, with their diameter and flow rate of arteries of knee joints measured before and after Uyghur sand therapy. It has been found that Uyghur sand therapy will increase the inner diameter of knee arteries and speed up the blood flow. Experimental results show that Uyghur sand therapy can help relieve obstacles in local blood flow. By choosing one volunteer for CT scanning, three-dimensional reconstruction of knee-joint arteries via MIMICS software is achieved. Calculation model is the established with numerical calculations performed by ANSYS software. According to the calculations, the blood flow of the knee arteries speeds up and the uniform distribution of velocity enlarges after Uyghur sand therapy, which further confirms the experimental results. Besides, the research also suggests that Uyghur sand therapy has stronger effect on blood flow of knee-joint arteries than the inner diameter.


Subject(s)
Arteries/physiology , Blood Flow Velocity/physiology , Knee Joint/physiology , Medicine, Chinese Traditional/methods , Models, Cardiovascular , Regional Blood Flow/physiology , Arteries/diagnostic imaging , Blood Pressure/physiology , Computer Simulation , Female , Humans , Knee Joint/blood supply , Knee Joint/diagnostic imaging , Male , Ultrasonography
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