A Spatiotemporal Deep Learning Framework for Scalp EEG-Based Automated Pain Assessment in Children.

OBJECTIVE: Common pain assessment approaches such as self-evaluation and observation scales are inappropriate for children as they require patients to have reasonable communication ability. Subjective, inconsistent, and discontinuous pain assessment in children may reduce therapeutic effectiveness and thus affect their later life. METHODS: To address the need for suitable assessment measures, this paper proposes a spatiotemporal deep learning framework for scalp electroencephalogram (EEG)-based automated pain assessment in children. The dataset comprises scalp EEG data recorded from 33 pediatric patients with an arterial puncture as a pain stimulus. Two electrode reduction plans in line with clinical findings are proposed. Combining three-dimensional hand-crafted features and preprocessed raw signals, the proposed transformer-based pain assessment network (STPA-Net) integrates both spatial and temporal information. RESULTS: STPA-Net achieves superior performance with a subject-independent accuracy of 87.83% for pain recognition, and outperforms other state-of-the-art approaches. The effectiveness of electrode combinations is explored to analyze pain-related cortical activities and correspondingly reduce cost. The two proposed electrode reduction plans both demonstrate competitive pain assessment performance qualitatively and quantitatively. CONCLUSION AND SIGNIFICANCE: This study is the first to develop a scalp EEG-based automated pain assessment for children adopting a method that is objective, standardized, and consistent. The findings provide a potential reference for future clinical research.

An Adaptive Multi-Dimensional Vehicle Driving State Observer Based on Modified Sage-Husa UKF Algorithm.

An accurate vehicle driving state observer is a necessary condition for a safe automotive electronic control system. Vehicle driving state observer is challenged by unknown measurement noise and transient disturbances caused by complex working conditions and sensor failure. For the classical adaptive unscented Kalman filter (AUKF) algorithm, transient disturbances will cause the failure of state estimation and affect the subsequent process. This paper proposes an AUKF based on a modified Sage-Husa filter and divergence calculation technique for multi-dimensional vehicle driving state observation. Based on the seven-degrees-of-freedom vehicle model and the Dugoff tire model, the proposed algorithm corrects the measurement noise by using modified Sage-Husa maximum posteriori. To reduce the influence of transient disturbance on the subsequent process, covariance matrix is updated after divergence is detected. The effectiveness of the algorithm is tested on the double lane change and Sine Wave road conditions. The robustness of the algorithm is tested under severe transient disturbance. The results demonstrate that the modified Sage-Husa UKF algorithm can accurately detect transient disturbance and effectively reduce the resulted accumulated error. Compared to classical AUKF, our algorithm significantly improves the accuracy and robustness of vehicle driving state estimation. The research in this paper provides a reference for multi-dimensional data processing under changeable vehicle driving states.