ABSTRACT
To date, there are no disease-specific instruments in Spanish to assess quality of life of patients with hidradenitis suppurativa. A multicentre study was previously carried out in Spain between 2016 and 2017 to develop the Hidradenitis Suppurativa Quality of Life-24 (HSQoL-24), a disease-specific questionnaire to assess quality of life in patients with hidradenitis suppurativa. The objectiv-es of this study are to revalidate the HSQoL-24 in Spanish with a larger sample of patients, and to present the English version. In this multi-centre study in Spain, patients with hidradenitis suppurativa completed the HSQoL-24, the Dermatology Life Quality Index and the Skindex-29. The Hurley staging system was used to assess the severity of the disease. Validation of the questionnaire was carried out in 130 patients, of whom 75 (57.7%) were women. This study demonstrates adequate values of reliability and validity of the HSQoL-24, confirming the previous test re-test validation and making this questionnaire one of wide clinical validity in terms of results perceiv-ed by patients.
Subject(s)
Hidradenitis Suppurativa , Quality of Life , Female , Hidradenitis Suppurativa/diagnosis , Humans , Reproducibility of Results , Severity of Illness Index , Surveys and QuestionnairesSubject(s)
Humans , Adult , Female , Skin Diseases/diagnosis , Skin Diseases/chemically induced , Aluminum Hydroxide/adverse effects , Pseudolymphoma/diagnosis , Pseudolymphoma/chemically induced , Diagnosis, Differential , Desensitization, Immunologic/adverse effects , Skin Diseases/therapy , Hypersensitivity, Immediate , Aluminum Hydroxide/administration & dosage , Injections , Pseudolymphoma/therapyABSTRACT
El penfigoide gestacional (PG) es una dermatosis ampollosa autoinmunitaria que generalmente aparece en el segundo y el tercer trimestres de la gestación, aunque no es infrecuente su debut en el puerperio inmediato. Clínicamente, consiste en la aparición de lesiones pruriginosas urticariformes y vesículo-ampollosas que comienzan, preferentemente, en el área periumbilical, con extensión centrífuga al resto de la superficie corporal. El PG está asociado a prematuridad y bajo peso. En el 5% de los casos los recién nacidos con madre con PG pueden presentar una erupción vesículo-ampollosa moderada debido al paso transplacentario de autoanticuerpos frente a inmunoglobulina G (IgG) maternos y que suele resolverse en poco tiempo. Presentamos el caso de una paciente puérpera con lesiones inicialmente acrales, con morfología similar a las del eritema exudativo multiforme, que posteriormente se extendieron a los brazos y las piernas y dieron lugar a grandes ampollas. El estudio histológico y la inmunofluorescencia directa fueron claves para el diagnóstico correcto y el posterior manejo terapéutico (AU)
Pemphigoid gestationis (PG) is an autoimmune blistering dermatosis that usually occurs in the second and third trimesters of pregnancy, although onset in the early puerperium is not infrequent. Clinically, this entity consists of pruritic urticarial blisters and vesicles that usually start in the periumbilical area and spread peripherally. PG is associated with prematurity and low birth weight. In 5% of cases, the neonates of mothers with PG may show moderate blistering-vesicular eruptions induced by autoantibodies transferred across the placenta, which usually resolve in a short time. We report the case of a puerperal patient who initially showed acral lesions with a morphology similar to those of exudative erythema multiforme, which subsequently spread to her arms, legs and face resulting in large blisters. Histological studies and direct immunofluorescence were essential to proper diagnosis and subsequent therapeutic management (AU)
Subject(s)
Humans , Female , Pregnancy , Adult , Pemphigoid, Bullous/complications , Pemphigoid, Bullous/therapy , Pregnancy Complications/diagnosis , Pregnancy Complications/therapy , Fluorescent Antibody Technique, Direct/methods , Adrenal Cortex Hormones/therapeutic use , Foot Dermatoses/complications , Hand Dermatoses/complications , Dermatomycoses/immunology , Beclomethasone/therapeutic use , Diagnosis, DifferentialABSTRACT
El Síndrome de Löfgren es una variante de presentación aguda de la sarcoidosis, de carácter benigno, caracterizada por la presencia de eritema nodoso, adenopatías hiliares bilaterales y poliartralgias o poliartritis. Presentamos un caso de Síndrome de Löfgren cuyo interés reside en el diagnóstico de una enfermedad sistémica como es la sarcoidosis a través de las lesiones cutáneas (AU)
Löfgren syndrome is an acute form sarcoidosis that is caracterized by erythema nodosum, bilateral hilar lymphadenopathy, and polyarthralgia or polyarthitis. We report a case of Löfgren syndrome whose interest lies in the diagnosis of a systemic disease like sarcoidosis throught cutaneous manifestation (AU)
Subject(s)
Humans , Sarcoidosis/complications , Erythema Nodosum/complications , Arthritis/complications , Adenoma/complicationsABSTRACT
Los síndromes paraneoplásticos son cuadros clínicos infrecuentes que se asocian a neoplasias, siendo a menudo precursores de éstas. La asociación de Síndrome de Sweet (SS) con procesos malignos está presente en el 20% de los casos, siendo las neoplasias de origen hematológico el 85% y el 15% los tumores sólidos. De entre los tumores sólidos asociados a SS, el adenocarcinoma de colon es muy infrecuente. Presentamos un caso clínico de SS con gran expresividad clínica, que nos llevó al diagnóstico de un adenocarcinoma de colon hasta ese momento desconocido (AU)
The paraneoplastic syndromes are a rare clinical conditions that are associated with malignancies, often being forerunners of these. Sweet´s syndrome (SS) associated with malignant process is present in 20% of cases, being hemalogic disorders 85% and solid tumors 15%. Among solid tumors associated with Sweet´s syndrome, adenocarcinoma of colon is infrequent. We report a case of SS with great clinical expressiveness, that led us to the diagnosis of colon adenocarcinoma which it had been unknown until then (AU)
Subject(s)
Humans , Sweet Syndrome/diagnosis , Colonic Neoplasms/diagnosis , Paraneoplastic Syndromes/diagnosis , Adenocarcinoma/pathologyABSTRACT
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