Subject(s)
Agammaglobulinemia/diagnosis , Livedo Reticularis/diagnosis , Severe Combined Immunodeficiency/diagnosis , Agammaglobulinemia/genetics , Biopsy , Child, Preschool , Diagnosis, Differential , Humans , Livedo Reticularis/genetics , Lower Extremity , Male , Severe Combined Immunodeficiency/geneticsABSTRACT
La práctica de tatuajes tienen más de 8000 años de antigüedad, existiendo un incremento continuo en la sociedad occidental en las últimos 3 décadas La introducción de una sustancia exógena en la pielpuede provocar una respuesta inmunológica en su contra, estando descritas reacciones cutáneas por hipersensibilidad a una variedad de pigmentos, las que se limitan al área de un determinado color,atribuyéndose a los materiales inyectados. El color más reportado en la literatura es el rojo, que tradicionalmente se confeccionaban a base dederivados del mercurio (cinabrio). Diversos patrones histológicos de reacción están descritos, siendo el más frecuente el liquenoide. Presentamos una serie de 10 pacientes con reacción de hipersensibilidad a tatuaje rojo, con patrón histológico predominante dereacción granulomatosa y con moderada respuesta a tratamiento. Es importante cuando se está ante un patrón granulomatoso de reacción descartar sarcoidosis sistémica e infecciones por micobacterias.
Subject(s)
Carbamates/adverse effects , Coloring Agents/adverse effects , Granuloma/chemically induced , Hypersensitivity/etiology , Nitriles/adverse effects , Skin Diseases/chemically induced , Adult , Aged , Diagnosis, Differential , Female , Granuloma/diagnosis , Humans , Hypersensitivity/diagnosis , Male , Middle Aged , Skin Diseases/pathologyABSTRACT
Infantile digital fibromatosis is a rare benign fibro/myofibroblastic proliferation that almost only occurs on the fingers and toes. It is characterized by bright, round, intracytoplasmic, eosinophilic inclusions. We present a case of infantile digital fibromatosis in a 6-years-old child.
Subject(s)
Fingers , Myofibromatosis/congenital , Subcutaneous Tissue/pathology , Biopsy , Child , Humans , Magnetic Resonance Imaging , Male , Myofibromatosis/pathology , Myofibromatosis/surgeryABSTRACT
The main source of vitamin D is synthesis in the skin during exposure to ultraviolet radiation. The existence of photoaggravated diseases and the increasing incidence of skin cancer have prompted recommendations to avoid the sun. Here, we study the status of vitamin D in a healthy population and its relation to their habits of sun exposure. To do so, we designed a cross-sectional study that included 177 healthy people. We analyzed parameters about demographic data, sun exposure, and protection habits and estimated vitamin D dietary intake. We performed blood tests to measure serum 25-hydroxyvitamin D [25(OH)D], calcium, phosphorus, and intact parathyroid hormone. Mean levels (± standard deviation) of 25(OH)D were 24.0 (± 8.5) ng/ml. Seventy-six percent of the population did not reach recommended levels of vitamin D (30 ng/ml), including 4.5% who were vitamin D deficient (< 10 ng/ml). Levels were higher in young people (P = 0.04) and those with more sun exposure (P = 0.04). Smoking was associated with an increased risk of hypovitaminosis D (odds ratio, 1.8; 95% confidence interval, 1.00-3.35). On the basis of our findings, we should consider the risk of hypovitaminosis when we recommend sun avoidance, especially in some risk groups, because the sun is the most important source of this vitamin.
Subject(s)
Aging/blood , Smoking/blood , Smoking/epidemiology , Vitamin D Deficiency/blood , Vitamin D Deficiency/epidemiology , Adult , Aged , Calcium/blood , Female , Habits , Humans , Male , Middle Aged , Parathyroid Hormone/blood , Phosphorus/blood , Risk Factors , Spain/epidemiology , Sunlight/adverse effects , Vitamin D/analogs & derivatives , Vitamin D/bloodABSTRACT
Presentamos una recién nacida con erosiones en flexuras, pápulas palmo-plantares y placas rosadas en la espalda sin afectación sistémica. La histologíamostraba un infiltrado histiocitario en dermis superior con epidermotropismo. La inmunohistoquímica resultó positiva para S100 y CD1a por loque se trataba de células de Langerhans. El estudio de extensión fue negativo. Las lesiones involucionaron espontáneamente en el plazo de 2 semanas,diagnosticándose de Reticulohistiocitosis congénita autoinvolutiva
A female newborn who presented erosions on folds, papules on palms and soles and red-brownish plaques on the back without involvement of internalorgans is reported. Light microscopy showed an histiocytic infiltrate in the papillary dermis with epidermotrophism. Inmunomarking with S100and CD1a was positive; therefore the histiocytes were Langerhans cells. The systemic evaluation excluded extracutaneous involvement. The cutaneouslesions resolved spontanously in two weeks so the case was diagnosed as Congenital self-healing reticulohistiocytosis
