ABSTRACT
An 18-year-old man, with serologically diagnosed adenovirus type 10 infection, had keratoconjunctivouveitis of both eyes after pharyngitis with transient increased intraocular pressure. Increased intraocular pressure, ranging from 46 to 28 mm Hg during medical therapy, lasted for about ten days in the early stage of the disease. Many punctate corneal opacities developed bilaterally two weeks later and disappeared within ten months. Analysis of the clinical findings demonstrated that the increased intraocular pressure may have been secondary glaucoma due to keratoconjunctivitis caused by adenovirus infection.
Subject(s)
Adenoviridae Infections/complications , Adenovirus Infections, Human/complications , Glaucoma/etiology , Keratoconjunctivitis/complications , Adenovirus Infections, Human/diagnosis , Adolescent , Corneal Opacity/diagnosis , Corneal Opacity/etiology , Glaucoma/diagnosis , Humans , Intraocular Pressure , Keratoconjunctivitis/diagnosis , Male , Pharyngitis/complicationsABSTRACT
Of 79 cases of rubella during the 1976--1977 rubella epidemic in Japan, 56 (70.9%) had mild conjunctivitis. Six (7.6%) showed epithelial keratitis, but the epidemically estimated incidence of keratitis was about 2% (two cases with rubella keratitis per 75 cases of rubella). No evidence of disease of the anterior chamber or the fundus was observed. Characteristic features of keratitis in juvenile rubella were fine punctate epithelial opacities mainly disseminated in the central area of the cornea. The punctate lesions were about 0.1 mm in diameter on an average, but varied in number from a few to about 100. In many cases, keratitis developed about one week after skin rash and disappeared within one week with no sequelae.
