Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 15 de 15
Filter
2.
Arch Orthop Trauma Surg ; 129(11): 1527-9, 2009 Nov.
Article in English | MEDLINE | ID: mdl-19169694

ABSTRACT

The boutonniere deformity is a well-known deformity in the fingers, however, its appearance on a lessor toe is extremely rare. In the present case, the deformity resulted from a rupture of the central slip of the extensor tendon and the shift of the lateral bands to the planter side after reduction of a traumatic planter dislocation of the PIP joint of the second toe. Surgical repair of the extensor mechanism brought good results.


Subject(s)
Foot Deformities, Acquired/surgery , Joint Dislocations/surgery , Toes/injuries , Toes/surgery , Adolescent , Humans , Male , Martial Arts/injuries
3.
J Cardiol ; 52(1): 30-8, 2008 Aug.
Article in English | MEDLINE | ID: mdl-18639775

ABSTRACT

To clarify the significance of adenosine triphosphate disodium stress myocardial perfusion imaging (ATP-MPI), we directly compared the findings of ATP-MPI with those of exercise stress myocardial perfusion imaging (Ex-MPI). ATP-MPI, Ex-MPI, and coronary angiography (CAG) were performed within 60 days in 17 coronary artery disease patients with mean age of 62.1+/-7.9 years. CAG revealed single-vessel disease (SVD) in 10 patients and multivessel disease (MVD) in seven patients. The summed stress score (SSS) of ATP-MPI was significantly higher than that of Ex-MPI (10.0 [7.8-14.3] vs. 8.0 [4-18], P<0.05). No difference in the SSS was observed between ATP-MPI and Ex-MPI in patients with SVD (8.0 [6.0-9.0] vs. 8.0 [6.0-10.0], NS), whereas this difference was significant in patients with MVD (15.0 [14.0-22.8] vs.9 [7.3-16.3], P<0.05). There was no difference in the summed rest score between ATP-MPI and Ex-MPI. The univariate logistic analysis showed that "MVD" was the significant factor influencing to the overt discrepancy between ATP-MPI and Ex-MPI (odds ratio: 9.0, 95% confidence interval: 1.07-75.84, P=0.043). The accuracy of ATP-MPI and Ex-MPI in detecting the territory of stenotic coronary vessel or previous myocardial infarction was 98.0% and 92.1% (NS), respectively. In conclusion, ATP-MPI is useful for detecting potential ischemic areas that cannot be detected by Ex-MPI, particularly in patients with MVD.


Subject(s)
Coronary Artery Disease/diagnosis , Exercise Test , Myocardial Perfusion Imaging , Adenosine Triphosphate , Coronary Angiography , Female , Humans , Male , Middle Aged
4.
Knee Surg Sports Traumatol Arthrosc ; 16(4): 393-5, 2008 Apr.
Article in English | MEDLINE | ID: mdl-18193196

ABSTRACT

We describe a case of popliteofibular ligament (PFL) injury, successfully treated with a new anatomic reconstruction technique looping the biceps femoris tendon (BT). The anterior half of the BT was split longitudinally from the fibular insertion, cut at the proximal end and left attached at the insertion. The proximal end of the BT was looped back in a slit made in the popliteal tendon (PT) at the original anatomical insertion site of the PFL, and passed through the tunnel from the posterior and the baseball suture was tightened on the anterior cortex of fibular head.


Subject(s)
Knee Injuries/surgery , Ligaments, Articular/surgery , Tendon Transfer/methods , Adult , Humans , Ligaments, Articular/injuries , Male , Suture Techniques
6.
Int Heart J ; 48(1): 1-9, 2007 Jan.
Article in English | MEDLINE | ID: mdl-17379974

ABSTRACT

Coronary perforation is an undesirable complication during percutaneous coronary intervention (PCI). We reviewed the cases of overt coronary perforation in our institute and analyzed their clinical backgrounds, the characteristics of the target lesion, management, and clinical outcomes. Between 1991 and 2005, we experienced 12 cases (0.35%) of coronary perforation in a total of 3415 PCI procedures. The perforation occurred during the use of debulking devices in 3 cases, immediately after stenting in 2, immediately after postdilatation of the stent in 2, and during wiring in 3 cases. Restoration was attempted by long inflation of a balloon in 7 cases, implantation of a covered stent graft in 1, and emergency surgical repair in 1 case. Subsequent cardiac tamponade occurred in 3 patients who required pericardiocentesis, and 1 patient died due to congestive heart failure. Administration of protamine was effective in stopping the bleeding in 6 patients, whereas continuation of antiplatelet therapy resulted in no overt rebleeding. Coronary perforation during PCI is a rare complication but is associated with significant morbidity and mortality. Intravenous administration of protamine is effective when it is used in conjunction with nonsurgical devices for initial management of perforation.


Subject(s)
Angioplasty, Balloon, Coronary/adverse effects , Cardiac Tamponade/etiology , Coronary Disease/therapy , Coronary Vessels/injuries , Aged , Aged, 80 and over , Cardiac Tamponade/diagnosis , Cardiac Tamponade/therapy , Coronary Angiography , Coronary Disease/diagnostic imaging , Endosonography , Female , Heparin Antagonists/administration & dosage , Heparin Antagonists/therapeutic use , Humans , Injections, Intravenous , Male , Middle Aged , Pericardiocentesis , Prognosis , Protamines/administration & dosage , Protamines/therapeutic use , Retrospective Studies , Rupture
8.
Clin Cardiol ; 29(6): 263-7, 2006 Jun.
Article in English | MEDLINE | ID: mdl-16796077

ABSTRACT

BACKGROUND: Experimental study has shown that blunted arterial baroreflex function markedly attenuated inotropic responses to a phosphodiesterase inhibitor (PDEI) even in normal hearts. However, whether arterial baroreflex function is related to the inotropic responsiveness to a PDEI has not been clarified in human heart failure (HF). HYPOTHESIS: The goal of this study was to examine the relationship between inotropic responses to a PDEI and arterial baroreflex sensitivity in human HF. METHODS: Twelve patients with HF were examined, and hemodynamic responses to milrinone (12.5, 25, and 50 microg/kg, intravenous injection) and arterial baroreflex sensitivity were assessed by pulse interval-left ventricular (LV) systolic pressure slope using nitroglycerin and phenylephrine. RESULTS: Milrinone (25 microg/kg) significantly increased LV dP/dt. Arterial baroreflex sensitivity was only one predictor of inotropic responses to milrinone by multivariate analysis; a strong positive correlation was also found between LV dP/dt and baroreflex sensitivity (y = 6.656X - 3.326, r = 0.93, p = 0.000). CONCLUSION: Inotropic effects of milrinone, a PDEI, correlated significantly with arterial baroreflex sensitivity, suggesting that the more baroreflex function was impaired, the more the inotropic effect of a PDEI was depressed in human HF.


Subject(s)
Baroreflex/physiology , Cardiotonic Agents/pharmacology , Heart Failure/physiopathology , Phosphodiesterase Inhibitors/pharmacology , Pressoreceptors/physiology , Adult , Aged , Baroreflex/drug effects , Female , Heart Failure/drug therapy , Humans , Male , Middle Aged , Milrinone/pharmacology
9.
J Nippon Med Sch ; 73(3): 158-63, 2006 Jun.
Article in English | MEDLINE | ID: mdl-16790984

ABSTRACT

Percutaneous aortic valvuloplasty is reportedly a useful tool for the management of critical and severe aortic stenosis with cardiogenic shock. However, early percutaneous coronary intervention for cardiogenic shock is beneficial for elderly patients with acute myocardial infarction. We describe a patient with critical aortic stenosis who presented with severe coronary stenosis of the left main trunk and the ostium of the right coronary artery. We performed percutaneous coronary intervention and percutaneous aortic valvuloplasty under intra-aortic balloon pump and percutaneous cardiopulmonary support. After these procedures, the cardiogenic shock was reversed, and the patient could be weaned from both intra-aortic balloon pump support and percutaneous cardiopulmonary support.


Subject(s)
Angioplasty, Balloon, Coronary , Aortic Valve/surgery , Cardiopulmonary Bypass , Shock, Cardiogenic/etiology , Shock, Cardiogenic/therapy , Aged, 80 and over , Aortic Valve Stenosis/complications , Aortic Valve Stenosis/therapy , Coronary Stenosis/complications , Coronary Stenosis/therapy , Female , Humans , Intra-Aortic Balloon Pumping , Treatment Outcome
10.
Nihon Rinsho ; 64(4): 691-9, 2006 Apr.
Article in Japanese | MEDLINE | ID: mdl-16613186

ABSTRACT

High-risk acute coronary syndrome is characterized by vulnerable-plaque with subocclusive thrombus and down-stream microemboli spreading minor myocardial damage, resulting in non-ST-elevation myocardial infarction. Advances in the understanding of the pathogenesis and consequences of acute coronary syndrome have stimulated development of novel biomarkers, and expanded their role in the different spectrum of the underlying pathophysiology, namely multi-biomarker strategy; consisted of biomarkers for 1) myocardial necrosis(membrane damage to myofibril necrosis), 2) plaque destabilization, 3) myocardial stress(ischemic stress per se and end-diastolic atrial or ventricular wall stress), 4) myocardial ischemia, and 5) inflammatory process. In this article, we review clinical importance of novel biomarkers referring our previous clinical investigation and other reports, especially troponin T for detection of minor myocardial damage associated with vulnerable plaque with thrombus/embolus, heart-type fatty acid -binding protein for earlier detection of myocardial damage and it's role for the rule-out triage, N-terminal pro-BNP for earlier risk stratification in cardiac emergency, and soluble CD40 ligand for earlier identification of plaque destabilization with platelet activation in non-ST-elevation acute coronary syndrome.


Subject(s)
Angina, Unstable/diagnosis , Myocardial Infarction/diagnosis , Angina, Unstable/etiology , Biomarkers/blood , CD40 Ligand/blood , Creatine Kinase, MB Form/blood , Fatty Acid Binding Protein 3 , Fatty Acid-Binding Proteins/blood , Humans , Myocardial Infarction/etiology , Myoglobin/blood , Natriuretic Peptide, Brain/blood , Syndrome , Troponin T/blood
11.
J Invasive Cardiol ; 18(3): 130-2, 2006 Mar.
Article in English | MEDLINE | ID: mdl-16598113

ABSTRACT

Angio-Seal, a vascular hemostasis device, has been shown to be safe and effective in rapidly achieving hemostasis after cardiac catheterization or coronary intervention. We propose that similar results can be obtained with Angio-Seal when removing an intra-aortic balloon pump (IABP). We studied 16 patients in whom Angio-Seal was utilized in IABP removals. The primary safety endpoint was a composite of major complications such as retroperitoneal bleeding, vessel occlusion, loss of distal pulses, vascular surgery or death, and minor complications such as hematoma (> 10 cm), AV fistula or pseudoaneurysm by 7 days after removal. The time-to-hemostasis was 2-5 minutes (mean 3.3 minutes). There were no instances of major or minor complications by the seventh day in any patients.


Subject(s)
Device Removal/methods , Hemostatic Techniques/instrumentation , Intra-Aortic Balloon Pumping/instrumentation , Adult , Aged , Aged, 80 and over , Collagen , Female , Humans , Male , Middle Aged , Time Factors , Treatment Outcome
12.
Int J Cardiol ; 111(2): 224-30, 2006 Aug 10.
Article in English | MEDLINE | ID: mdl-16185779

ABSTRACT

BACKGROUND: Elevated B-type natriuretic peptide (BNP) levels show prognostic significance in patients with non-ST elevation acute coronary syndromes, but the underlying pathophysiology remains unclear. METHODS: Two hundred and eighteen consecutive patients with non-ST elevation acute coronary syndromes were studied retrospectively. We compared clinical characteristics between groups with plasma BNP levels above or below the median value, and performed multiple logistic regression analysis to identify independent predictors of supramedian BNP levels. RESULTS: Patients with supramedian BNP (>or=134 pg/ml) were more likely to be elderly (>or=75 years) with diabetes, prior myocardial infarction, and a history of coronary artery bypass grafting. They also had higher cardiac marker levels, a higher Killip class, a lower left ventricular ejection fraction, renal insufficiency (creatinine>or=1.5 mg/dl), and more 3-vessel disease. In multivariate analysis, the strongest independent predictor of supramedian BNP levels was 3-vessel disease (chi(2)=12.1), followed by old age (chi(2)=10.3), renal insufficiency (chi(2)=5.0), higher Killip class (chi(2)=4.2), and lower left ventricular ejection fraction (chi(2)=4.1). All 11 patients dying in hospital had supramedian BNP levels. Its elevation reflected the risk of 3-vessel disease and coronary artery bypass grafting regardless of troponin status. CONCLUSION: In unselected patients with non-ST elevation acute coronary syndromes, an increase of BNP is correlated with the extent of myocardial ischemia, age, renal insufficiency, and ventricular dysfunction. It may be a useful biomarker integrating conventional risk factors for risk stratification in this population.


Subject(s)
Coronary Disease/blood , Natriuretic Peptide, Brain/blood , Aged , Biomarkers/blood , Coronary Artery Bypass , Coronary Disease/classification , Coronary Disease/mortality , Coronary Disease/physiopathology , Female , Hospital Mortality , Humans , Male , Middle Aged , Myocardial Infarction/blood , Myocardial Infarction/mortality , Myocardial Infarction/physiopathology , Myocardial Infarction/surgery , Prognosis , Survival Analysis
13.
Circ J ; 69(7): 774-9, 2005 Jul.
Article in English | MEDLINE | ID: mdl-15988101

ABSTRACT

BACKGROUND: The clinical implications of applying the new criteria of acute myocardial infarction (AMI) with cardiac troponins in terms of their diagnostic and prognostic impact in patients with suspected acute coronary syndromes (ACS) have not been well evaluated. METHODS AND RESULTS: The study group comprised 973 consecutive patients who were diagnosed as having ACS with or without ST elevation (STE). They were divided into 3 groups: unstable angina (UA) group (n=195) representing patients with no significant elevations of creatine kinase (CK) and troponin T (TnT); TnT-myocardial infarction (MI) group (n=170) with TnT elevation and no CK elevation (additionally detected AMI by the new criteria); CK-MI group (n=608) with significant elevation of CK (AMI by the old criteria). In the TnT-MI group, 140 (76%) patients had non-STE ACS. In-hospital mortality rates for STE ACS were 0%, 2.5% and 9.7% in the UA, TnT-MI and CK-MI groups, respectively. The corresponding values for non-STE ACS were 1.8%, 4.6%, and 16.5%, respectively (p<0.0001), suggesting a pivotal role of TnT. In multiple logistic regression analysis, significant CK elevation was selected as an independent predictor of in-hospital death in concurrence with age > or =75 years, prior MI, shock and low left ventricular ejection fraction in non-STE ACS. CONCLUSIONS: The new criteria result in a substantial increase in the diagnosis of AMI from non-STE ACS in particular. They assist greatly in detailed risk stratification of ACS patients, notably in cooperation with the old CK criteria.


Subject(s)
Angina, Unstable/diagnosis , Creatine Kinase/blood , Myocardial Infarction/diagnosis , Troponin T/blood , Acute Disease , Aged , Angina, Unstable/blood , Angina, Unstable/complications , Biomarkers/blood , Female , Hospital Mortality , Humans , Male , Middle Aged , Myocardial Infarction/blood , Myocardial Infarction/complications , Predictive Value of Tests , Syndrome
14.
Circ J ; 69(4): 397-403, 2005 Apr.
Article in English | MEDLINE | ID: mdl-15791032

ABSTRACT

BACKGROUND: A rapid laboratory test for diagnosis of acute aortic dissection (AAD) has not been available. We performed this prospective study to determine the utility of a rapid bedside D-dimer (DD) assay for detection of AAD. METHODS AND RESULTS: Patients with suspected AAD were recruited and their DD levels were measured by rapid bedside assay. They were divided into 2 groups according to enhanced computed tomography findings: an AAD group (n = 30) and a non-AAD group (n = 48). The median DD level was higher in the AAD group (1.80 microg/ml) than in the non-AAD group (0.42 microg/ml) (p = 0.000). The rapid bedside DD assay showed 100% sensitivity, 54% specificity, 58% positive predictive value and 100% negative predictive value for detection of AAD with a normal DD level of up to 0.5 microg/ml. The combination of DD level >0.5 microg/ml and systolic blood pressure > or = 180 mmHg showed 86% positive predictive value for detection of AAD. Conclusions We conclude that the rapid bedside DD assay is a highly sensitive method for early exclusion of AAD in patients with chest and/or back pain suggestive of AAD. Acute aortic dissection is highly probable if a rapid DD assay shows the elevated DD level with systolic blood pressure > or = 180 mmHg on admission.


Subject(s)
Aortic Aneurysm/diagnosis , Aortic Dissection/diagnosis , Fibrin Fibrinogen Degradation Products/analysis , Point-of-Care Systems/standards , Aged , Back Pain/diagnosis , Chest Pain/diagnosis , Diagnosis, Differential , Female , Humans , Hypertension , Male , Middle Aged , Myocardium/chemistry , Predictive Value of Tests , Prospective Studies , Sensitivity and Specificity , Tomography, X-Ray Computed
15.
Circ J ; 68(11): 988-92, 2004 Nov.
Article in English | MEDLINE | ID: mdl-15502377

ABSTRACT

BACKGROUND: Acute massive or submassive pulmonary embolism (PE) has high mortality, but the clinical course according to the location of onset (ie, in-hospital or out-of-hospital) is unknown. METHODS AND RESULTS: In the present study 56 consecutive patients with acute massive or submassive PE were studied retrospectively and a comparison made of the clinical characteristics, and outcomes between in-hospital onset (Group A) and out-of-hospital onset (Group B). Patients in Group A (n=28) had more frequent comorbidities with hemodynamic instability (54% vs 4%, p<0.0001) and temporary risk factors (93% vs 11%, p<0.0001), whereas patients in Group B (n=28) had a longer duration of symptoms (median: 5.5 days vs 0.5 day; p<0.0001), and had higher systolic pulmonary artery pressure (63+/-17 mmHg vs 46+/-12 mmHg, p=0.0006). Although in-hospital mortality did not differ between the 2 groups, the recurrence rate was higher in Group B (23% vs 0%, p=0.03). CONCLUSIONS: Patients who had in-hospital onset of PE had mostly temporary risk factors, unstable hemodynamics and a lower recurrence rate compared with the cases of out-of-hospital onset. In cases of in-hospital onset, prompt diagnosis and suitable treatment is needed to prevent fatalities and cases of out-of-hospital onset should be followed carefully for recurrence.


Subject(s)
Hospitalization , Pulmonary Embolism/physiopathology , Acute Disease , Aged , Arteries , Female , Gases/blood , Hemodynamics , Hospital Mortality , Humans , Male , Middle Aged , Pulmonary Embolism/blood , Pulmonary Embolism/etiology , Pulmonary Embolism/therapy , Recurrence , Retrospective Studies , Risk Factors , Severity of Illness Index , Treatment Outcome
SELECTION OF CITATIONS
SEARCH DETAIL
...