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1.
Cultur Divers Ethnic Minor Psychol ; 28(4): 483-492, 2022 Oct.
Article in English | MEDLINE | ID: mdl-35797155

ABSTRACT

OBJECTIVES: We investigate how Mexican-heritage mothers' socialization beliefs and strategies contribute to their preschool children's school readiness. While Latinx children typically start kindergarten with strong social competencies, they also start with less strong early literacy and math skills, in comparison with their non-Latinx peers. We propose that-paralleling Lareau's (2003) theory of "concerted cultivation," whereby White, middle-class parents purportedly display great intentionality in nurturing the academic and extracurricular skills of their children-Mexican-heritage mothers purposefully cultivate their children's social-emotional skills. METHODS: Using structured interviews and home observations over a 14-month period, we follow 23 Mexican-heritage mothers and their 24 preschool children. RESULTS: Drawing on ecocultural theory, Mexican-heritage mothers engage their preschool children in a concerted fashion to develop their social-emotional competence. Specifically, they: (a) articulate the role of children's social-emotional skills vis-à-vis academic skills related to school readiness; (b) delineate the character of their children's social-emotional skills; and (c) promote social-emotional skills through intention-filled parenting practices relevant to their cultural contexts. CONCLUSIONS: Understanding parents' "concerted cultivation" in differing cultural contexts may facilitate teachers' use of practices that better align with families' home practices and more effectively support the learning of Latinx children across academic domains. (PsycInfo Database Record (c) 2022 APA, all rights reserved).


Subject(s)
Mothers , Parenting , Female , Child, Preschool , Humans , Parenting/psychology , Mothers/psychology , Socialization , Parent-Child Relations , Schools
2.
Acad Med ; 96(3): 433-440, 2021 03 01.
Article in English | MEDLINE | ID: mdl-32496285

ABSTRACT

PURPOSE: Despite the importance of training in ambulatory care settings for residents to acquire important competencies, little is known about the organizational and environmental factors influencing the relative amount of time primary care residents train in ambulatory care during residency. The authors examined factors associated with postgraduate year 1 (PGY-1) residents' ambulatory care training time in Accreditation Council for Graduate Medical Education (ACGME)-accredited primary care programs. METHOD: U.S.-accredited family medicine (FM) and internal medicine (IM) programs' 2016-2017 National Graduate Medical Education (GME) Census data from 895 programs within 550 sponsoring institutions (representing 13,077 PGY-1s) were linked to the 2016 Centers for Medicare and Medicaid Services Cost Reports and 2015-2016 Area Health Resource File. Multilevel regression models examined the association of GME program characteristics, sponsoring institution characteristics, geography, and environmental factors with PGY-1 residents' percentage of time spent in ambulatory care. RESULTS: PGY-1 mean (standard deviation, SD) percent time spent in ambulatory care was 25.4% (SD, 0.4) for both FM and IM programs. In adjusted analyses (% increase [standard error, SE]), larger faculty size (0.03% [SE, 0.01], P < .001), sponsoring institution's receipt of Teaching Health Center (THC) funding (6.6% (SE, 2.7), P < .01), and accreditation warnings (4.8% [SE, 2.5], P < .05) were associated with a greater proportion of PGY-1 time spent in ambulatory care. Programs caring for higher proportions of Medicare beneficiaries spent relatively less time in ambulatory care (< 0.5% [SE, 0.2], P < .01). CONCLUSIONS: Ambulatory care time for PGY-1s varies among ACGME-accredited primary care residency programs due to the complex context and factors primary care GME programs operate under. Larger ACGME-accredited FM and IM programs and those receiving federal THC GME funding had relatively more PGY-1 time spent in ambulatory care settings. These findings inform policies to increase resident exposure in ambulatory care, potentially improving learning, competency achievement, and primary care access.


Subject(s)
Accreditation/economics , Ambulatory Care/organization & administration , Family Practice/education , Internal Medicine/education , Internship and Residency/methods , Accreditation/standards , Adult , Ambulatory Care/standards , Cross-Sectional Studies , Education, Medical, Graduate/standards , Environment , Humans , Internship and Residency/economics , Medicaid/economics , Medicare/economics , Time Factors , United States/epidemiology
3.
Eval Rev ; 44(2-3): 111-144, 2020 04.
Article in English | MEDLINE | ID: mdl-32787579

ABSTRACT

Charter schools place competitive pressure on school districts to retain students and public funding. Many districts also have moved to decentralize control of budgets and teacher hiring down to school principals, independent of competitive pressures. But almost no evaluation evidence gauges the effectiveness of charter-like schools, relative to traditional public schools. We find that autonomous pilot schools in Los Angeles enroll more low-income and Spanish-speaking students, compared with traditional schools. Pilot pupils are significantly less likely to exit the school district. But pilot pupils displayed lower test scores in mathematics and fell slightly below traditional students in English-language arts, taking into account prior performance and their propensity to enter pilot schools. We tracked 6,732 students entering pilot high schools between 2008 and 2012, statistically matched in multiple ways with traditional peers from identical sending middle schools. We discuss the advantages of our evaluation strategy and the implications of our findings for education leaders and policy makers.


Subject(s)
Academic Success , Competitive Behavior , Schools , Student Dropouts , Adolescent , Female , Humans , Los Angeles , Male
4.
Am J Public Health ; 109(11): 1557-1563, 2019 11.
Article in English | MEDLINE | ID: mdl-31536398

ABSTRACT

Objectives. To examine the impact of physical education (PE) litigation on changes in cardio-respiratory fitness among racially/ethnically and socioeconomically diverse students.Methods. We used annual school-level data for all California schools with measures of fifth graders' cardio-respiratory fitness spanning 2007-2008 through 2017-2018. A difference-in-difference design assessed changes before and after lawsuits in the proportion of students meeting fitness standards in schools in districts that were parties to PE lawsuits (n = 2715) versus in schools in districts not involved (n = 3152). We ran separate models with the proportion of students meeting fitness standards by sex, race/ethnicity, and low-income status as outcomes.Results. PE litigation led to a 1-percentage-point increase in the proportion of fifth-grade students meeting cardio-respiratory fitness standards (95% confidence interval [CI] = 0.03%, 2.0%). Effects were especially pronounced for female (1.3-percentage-point increase; 95% CI = 0.1%, 2.5%), African American (3.4-percentage-point increase; 95% CI = 0.5%, 6.2%), and low-income (2.8-percentage-point increase; 95% CI = 0.5%, 6.0%) students.Conclusions. Schools in districts subject to PE litigation showed greater improvements in student fitness, particularly among students typically at higher risk for inactivity and low fitness. Litigation may be an impactful tool for enforcing PE provision in accordance with the law.


Subject(s)
Cardiorespiratory Fitness/physiology , Physical Education and Training/legislation & jurisprudence , California , Child , Female , Humans , Male , Poverty , Racial Groups , Sex Factors , Socioeconomic Factors
6.
J Racial Ethn Health Disparities ; 3(1): 129-37, 2016 Mar.
Article in English | MEDLINE | ID: mdl-26896112

ABSTRACT

OBJECTIVE: The aims of this study are to describe growth trajectories in the body mass index (BMI) among the major racial and ethnic groups of US children and to identify predictors of children's BMI trajectories. METHODS: The Early Childhood Longitudinal Study-Birth Cohort (ECLS-B) was used to identify predictors of BMI growth trajectories, including child characteristics, maternal attributes, home practices related to diet and social behaviors, and family sociodemographic factors. Growth models, spanning 48 to 72 months of age, were estimated with hierarchical linear modeling via STATA/Xtmixed methods. RESULTS: Approximately one-third of 4-year-old females and males were overweight and/or obese. African-American and Latino children displayed higher predicted mean BMI scores and differing mean BMI trajectories, compared with White children, adjusting for time-independent and time-dependent predictors. Several factors were significantly associated with lower mean BMI trajectories, including very low birth weight, higher maternal education level, residing in a two-parent household, and breastfeeding during infancy. Greater consumption of soda and fast food was associated with higher mean BMI growth. Soda consumption was a particularly strong predictor of mean BMI growth trajectory for young Black children. Neither the child's inactivity linked to television viewing nor fruit nor vegetable consumption was predictive of BMI growth for any racial/ethnic group. CONCLUSION: Significant racial and ethnic differences are discernible in BMI trajectories among young children. Raising parents' and health practitioners' awareness of how fast food and sweetened-beverage consumption contributes to early obesity and growth in BMI-especially for Blacks and Latinos-could improve the health status of young children.


Subject(s)
Black or African American/statistics & numerical data , Body Mass Index , Health Status Disparities , Hispanic or Latino/statistics & numerical data , Pediatric Obesity/ethnology , Child, Preschool , Female , Humans , Longitudinal Studies , Male , Risk Factors , United States , White People/statistics & numerical data
7.
Cultur Divers Ethnic Minor Psychol ; 21(2): 181-90, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25364833

ABSTRACT

The question of how home activities advance the early social and cognitive development of Latino children receives growing attention from psychologists and social scientists. Some scholars and practitioners, focused on promoting "school readiness," frame the problem as weak parenting, signaled by insufficient rich language or academic skills. Other theorists, rooted in ecocultural theory, argue that early socialization and cognitive engagement are culturally situated within routine home activities. These activity structures vary and change over time as families acculturate, adapting to local social ecologies. Little is known empirically about the activity structures within Latino homes, including how young children participate. We detail the social architecture and cognitive engagement pertaining to 6 prevalent home activities in which 24 Mexican American 4-year-olds were engaged over 14 months. We then report how children participate in these 6 activities, and their potential relevance to the cognitive skills gap seen at school entry. We found that children's activities reproduced heritage language, symbols, and knowledge less often than suggested in prior literature; children's typical level of cognitive engagement varied greatly among tasks; and the distribution of time spent in activities is associated with the mother's school attainment and home language.


Subject(s)
Cognition/physiology , Family Characteristics/ethnology , Mexican Americans/psychology , Socialization , Acculturation , Adaptation, Psychological , Child Development/physiology , Child, Preschool , Female , Humans , Male , Mothers/psychology , Parenting/psychology , Schools , Social Behavior , Social Environment , Socioeconomic Factors , United States
8.
Matern Child Health J ; 17(9): 1701-11, 2013 Nov.
Article in English | MEDLINE | ID: mdl-23149800

ABSTRACT

Latino toddlers fall behind White peers at 24 months of age in oral language and interactive skills with their mothers in English or Spanish. But Latino children enter kindergarten with social skills that rival White peers, despite social-class disparities. We ask whether cognitive trajectories widen during the 24-48 month period, how these patterns differ for Latinos, especially Mexican-Americans, and whether similar gaps in social-emotional growth appear. We analyzed growth patterns for a nationally representative birth sample (n = 4,690) drawn in 2001, estimating levels of change in development from 24 to 48 months of age, focusing on Latino subgroups. The mean gap in cognitive processing for Mexican-American children, already wide at 24-months of age relative to Whites (three-fourths of a standard deviation), remained constant at 48 months. But differences in social-emotional status were statistically insignificant at both 24 and 48 months. Mexican-American mothers were observed to be equally warm and supportive relative to White peers during interaction tasks. Yet the former group engaged less frequently in cognitive facilitation, oral language, and preliteracy activities in the home. Growth in both cognitive and social domains was considerably lower in larger families, placing children raised in poor or Spanish-speaking homes within a large household at greater risk of delays. Pediatricians and practitioners must carefully gauge the social-emotional well-being of Latino children, in developmental surveillance activities. Growth in cognitive and social domains unfolds independently for children of Mexican heritage, even when raised in economically poor families.


Subject(s)
Child Development , Cognition , Mexican Americans/psychology , Social Behavior , Adult , Child, Preschool , Female , Humans , Least-Squares Analysis , Male , United States , White People/psychology
9.
Child Dev ; 83(5): 1510-26, 2012.
Article in English | MEDLINE | ID: mdl-22966920

ABSTRACT

Poverty-related developmental-risk theories dominate accounts of uneven levels of household functioning and effects on children. But immigrant parents may sustain norms and practices-stemming from heritage culture, selective migration, and social support-that buffer economic exigencies. Comparable levels of social-emotional functioning in homes of foreign-born Latino mothers were observed relative to native-born Whites, despite sharp social-class disparities, but learning activities were much weaker, drawing on a national sample of mothers with children aging from 9 to 48months (n=5,300). Asian-heritage mothers reported weaker social functioning-greater martial conflict and depression-yet stronger learning practices. Mothers' migration history, ethnicity, and social support helped to explain levels of functioning, after taking into account multiple indicators of class and poverty.


Subject(s)
Emigrants and Immigrants/psychology , Emigration and Immigration , Family Relations/ethnology , Learning , Child , Child, Preschool , Culture , Educational Status , Ethnicity/ethnology , Ethnicity/psychology , Humans , Infant , Interpersonal Relations , Mothers/statistics & numerical data , Poverty , Social Class , Social Identification , Social Support , United States
10.
Dev Psychol ; 46(3): 559-65, 2010 May.
Article in English | MEDLINE | ID: mdl-20438170

ABSTRACT

Two generations ago, Latino children and families were often defined as disadvantaged, even "culturally deprived," by psychologists, social scientists, and pediatric researchers. Since then, empirical work from several disciplines has yielded remarkable discoveries regarding the strengths of Latino families and resulting benefits for children. Theoretical advances illuminate how variation in the child's culturally bounded context or developmental niche reproduces differing socialization practices, forms of cognition, and motivated learning within everyday activities. This review sketches advances in 4 areas: detailing variation in children's local contexts and households among Latino subgroups, moving beyond Latino-White comparisons; identifying how parenting goals and practices in less acculturated, more traditional families act to reinforce social cohesion and support for children; identifying, in turn, how pressures on children and adolescents to assimilate to novel behavioral norms offer developmental risks, not only new opportunities; and seeing children's learning and motivation as situated within communities that exercise cognitive demands and social expectations, advancing particular forms of cognitive growth that are embedded within social participation and the motivated desire to become a competent member. This review places the articles that follow within such contemporary lines of work. Together they yield theoretical advances for understanding the growth of all children and adolescents, who necessarily learn and develop within bounded cultural or social-class groups.


Subject(s)
Child Development , Family/ethnology , Hispanic or Latino/psychology , Parenting/ethnology , Adolescent , Adult , Child , Cognition , Family/psychology , Humans , Parenting/psychology , Social Environment
11.
Dev Psychol ; 46(3): 566-78, 2010 May.
Article in English | MEDLINE | ID: mdl-20438171

ABSTRACT

Early research on the socialization of Latino children has posited that mothers exercise authoritarian practices, compared with lateral reasoning (authoritative) strategies emphasized by Anglo mothers. This work aimed to categorize fixed types of parenting practices tied to the mother's personality rather than to culturally bounded contexts; it often ignored the emotional warmth or harshness present in compliance attempts and relied on interview questions rather than naturalistic observation. We built from ecocultural theory to observe daily home activities in which Mexican American mothers attempted to correct their young child's behavior or encourage completion of a task (compliance attempt). We observed 24 first- or second-generation mothers and their 4-year-old children and analyzed the activity contexts and multiple forms of 1,477 compliance attempts. Mothers typically led with direct verbal commands in their attempt to achieve compliance. Many blended commands with other compliance strategies, rather than repeating simple behaviors. Drawing on Crockenberg and Litman's (1990) differentiation of variable compliance strategies, we find that most mothers relied on low power-assertive methods, including verbal commands, rather than inductive strategies that involved reasoning. Few compliance episodes prompted high power-assertive or harsh strategies. The degree of reliance on verbal commands and the complexity of mothers' repertoires appear to be related to their education and acculturation levels.


Subject(s)
Child Rearing/ethnology , Mexican Americans/psychology , Mother-Child Relations/ethnology , Mothers/psychology , Socialization , Acculturation , Adult , Child Development , Child Rearing/psychology , Child, Preschool , Educational Status , Emotions , Female , Humans , Male , Maternal Behavior/ethnology , Maternal Behavior/psychology , Parenting/ethnology , Parenting/psychology , Personality
12.
Dev Psychol ; 46(3): 579-92, 2010 May.
Article in English | MEDLINE | ID: mdl-20438172

ABSTRACT

We know that social competence contributes to young children's adaptation to, and cognitive learning within, classroom settings. Yet initial evidence is mixed on the social competencies that Latino children bring to kindergarten and the extent to which these skills advance cognitive growth. Building from ecocultural and developmental-risk theory, this paper shows children's social competence to be adaptive to the normative expectations and cognitive requirements of culturally bounded settings in both the home and classroom. Latino socialization in the home may yield social competencies that teachers value rather than reflect "risk factors" that constrain children's school readiness. We draw on the Early Childhood Longitudinal Study, kindergarten cohort (N = 19,590) to detail 5 social competencies at entry to school--self-control, interpersonal skills, approaches to learning, internalizing and externalizing problem behaviors--and to examine variability among Latino subgroups. We then test the extent to which baseline variation in social competence accounts for children's cognitive growth during the kindergarten year. We find that Latino children from poor, but not middle-class, families display weaker social competencies vis-à-vis White children (all relationships p < or = .05). Social competence levels contribute to Latino children's cognitive growth, which is shaped most strongly by positive approaches to learning. The disparities in competencies observed for Latino children from poor families, relative to White children, are significant yet much smaller than gaps in baseline levels of mathematical understanding. We discuss how the consonance or mismatch between competencies acquired at home and those valued by teachers must consider cultural differences, social-class position, and variation among diverse Latino subgroups.


Subject(s)
Adaptation, Psychological , Comprehension , Hispanic or Latino/psychology , Schools , Socialization , Child Development , Child, Preschool , Cognition , Cross-Cultural Comparison , Female , Humans , Interpersonal Relations , Male , Mathematics , Personality Development , Social Behavior , Social Environment , Socioeconomic Factors , White People
13.
Pediatrics ; 125(2): e324-32, 2010 Feb.
Article in English | MEDLINE | ID: mdl-20100750

ABSTRACT

OBJECTIVES: Infants born to immigrant mothers, including Hispanic mothers, display birth weight and mortality advantages, compared with other disadvantaged groups. We examined prenatal biological factors and maternal practices that account for this advantage. Then we estimated the extent to which healthy birth outcomes, along with maternal and family factors, contribute to the health and cognitive functioning of Hispanic infants. METHODS: A representative US sample of 8114 newborns, including 1450 newborns of Hispanic mothers, was drawn randomly in 2001. We compared the mean attributes of infants in subgroups that vary in maternal practices, family attributes, and acculturation levels. We accounted for variations in newborns' gestational age and size for gestational age and their health status and cognitive functioning at 9 months of age. RESULTS: Mexican-heritage and less-acculturated mothers were no more likely than white mothers to bear premature or small-for-gestational age infants, despite large social class disparities, which was explained in part by Hispanic women's low level of prenatal tobacco use. Parenting practices and lower class status of Hispanic mothers then began to slow infants' cognitive development, compared with white infants, because of weaker maternal education and cognitive facilitation during interaction tasks and larger family size. CONCLUSIONS: These findings extend earlier research, detailing healthy births among most immigrant Hispanic women. Robust birth outcomes contribute to the early health and cognitive growth of Hispanic infants, but risk factors linked to maternal and home practices overtake these early protective factors by late infancy. Robust births and early health indicators displayed by Hispanic infants should not distract pediatricians from attending to uneven cognitive growth.


Subject(s)
Health Status , Hispanic or Latino , Infant Welfare , Acculturation , Age Factors , Birth Weight , Female , Humans , Infant , Infant, Newborn , Mexican Americans , Pregnancy , Pregnancy Outcome , Social Support , Socioeconomic Factors
14.
Matern Child Health J ; 13(6): 755-68, 2009 Nov.
Article in English | MEDLINE | ID: mdl-19554440

ABSTRACT

Epidemiologists have shown how birth outcomes are generally robust for immigrant Latina mothers, despite often situated in poor households, advanced by their strong prenatal and nutritional practices. But little is known about (1) how these protective factors may differ among Latino subgroups, (2) the extent to which birth outcomes, ongoing maternal practices, and family supports advance Latino toddlers' health and physical growth, and (3) whether the same processes advance toddlers' early cognitive growth. We drew on a national probability sample of 8,114 infants born in 2001, including 1,450 of diverse Latino origins. Data come from birth records, maternal interviews when the child was 9 and 24 months of age, and direct assessments of health status, physical growth, and cognitive proficiencies. Descriptive analyses compared Mexican-heritage and other Latino mothers and toddlers relative to middle-class whites. Multivariate regression techniques identified predictors of child health, weight, and BMI, as well as cognitive proficiencies at 24 months. Infants of Mexican-heritage or less acculturated Latina mothers displayed robust birth outcomes, compared with other ethnic groups. The low incidence of premature births and low birthweight among these mothers continued to advance their cognitive growth through 24 months of age. Yet Latino children overall displayed smaller gains in cognitive proficiencies between 9 and 24 months, compared with middle-class populations, attributable to Latinas' lower levels of maternal education, weaker preliteracy practices, and a higher ratio of children per resident adult. Health practitioners should recognize that many Latina mothers display healthy prenatal practices and give birth to robust infants. But these early protective factors do not necessarily advance early cognitive growth. Screening practices, early interventions, and federal policy should become more sensitive to these countervailing dynamics.


Subject(s)
Child Development/physiology , Cognition , Emigration and Immigration/statistics & numerical data , Hispanic or Latino/statistics & numerical data , Adult , Body Mass Index , Educational Status , Female , Health Status , Humans , Infant , Longitudinal Studies , Maternal Behavior/ethnology , Mothers , Risk , Socioeconomic Factors , United States , Young Adult
16.
Child Dev ; 75(1): 47-65, 2004.
Article in English | MEDLINE | ID: mdl-15015674

ABSTRACT

Young children in poor communities are spending more hours in nonparental care because of policy reforms and expansion of early childhood programs. Studies show positive effects of high-quality center-based care on children's cognitive growth. Yet, little is known about the effects of center care typically available in poor communities or the effects of home-based care. Using a sample of children who were between 12 and 42 months when their mothers entered welfare-to-work programs, this paper finds positive cognitive effects for children in center care. Children also display stronger cognitive growth when caregivers are more sensitive and responsive, and stronger social development when providers have education beyond high school. Children in family child care homes show more behavioral problems but no cognitive differences.


Subject(s)
Child Behavior Disorders/etiology , Child Day Care Centers , Cognition Disorders/etiology , Early Intervention, Educational , Poverty/psychology , Socialization , Child Behavior Disorders/psychology , Child, Preschool , Cognition Disorders/psychology , Female , Humans , Infant , Male , Maternal Behavior , Mother-Child Relations , Mothers/education , Personality Assessment , Social Adjustment , Social Environment , Vocational Education , Women, Working/psychology
17.
Blood ; 102(5): 1920-6, 2003 Sep 01.
Article in English | MEDLINE | ID: mdl-12750162

ABSTRACT

Induction of transplantation tolerance to alloantigens without general immunosuppression remains an enduring challenge. Injecting a donor-specific transfusion (DST) of spleen cells together with blocking alphaCD154 antibody prior to graft transplantation is an effective way to induce long-lived graft acceptance. Using a novel T-cell receptor (TCR) transgenic (Tg) model of CD4+ T-cell-mediated rejection, this study sheds new insights into the cellular basis for enhanced graft survival induced by DST and alphaCD154. The study shows that DST and alphaCD154 induce an early, robust, abortive expansion of the Tg T cells that results in profound anergy. This is contrasted with the more delayed, regional, productive response elicited by an allogeneic graft. Studies show that the induction of tolerance to the allograft induced by DST is mediated by indirect presentation by host antigen-presenting cells. Based on these observations, we conclude that DST and alphaCD154 preemptively tolerize the alloreactive T-cell compartment to prohibit subsequent responses to the immunogenic allograft.


Subject(s)
Antigen Presentation/immunology , CD4-Positive T-Lymphocytes/immunology , Genes, RAG-1/genetics , Immune Tolerance/immunology , Skin Transplantation/immunology , Animals , Antibodies/pharmacology , CD4-Positive T-Lymphocytes/cytology , CD4-Positive T-Lymphocytes/transplantation , CD40 Ligand/immunology , CD40 Ligand/metabolism , Clone Cells , Graft Rejection/immunology , Graft Survival/immunology , Isoantigens/immunology , Mice , Mice, Inbred BALB C , Mice, Inbred C57BL , Mice, Knockout , Spleen/cytology , Tissue Donors
18.
Future Child ; 12(1): 96-119, 2002.
Article in English | MEDLINE | ID: mdl-11980041

ABSTRACT

For the changes under welfare reform to positively affect children, the gains that mothers make from employment must lead to improvements in children's daily settings at home, in child care, at school, or in the community. This article focuses on the role child care can play in promoting the development of, and life opportunities for, low-income children. Key observations include: Total federal and state funding for child care for welfare and working poor families has increased dramatically since welfare reform, from $2.8 billion in 1995 to $8.0 billion in 2000. The majority of welfare mothers tend to rely on informal child care arrangements when first participating in welfare-to-work programs, but as they move off welfare and into more stable jobs, they are more likely to choose a center or a family child care home. Although children from poor households stand to benefit the most from high-quality care, they are less likely to be enrolled in high-quality programs than are children from affluent families, partly due to uneven access to high-quality options in their neighborhoods. Less than one-quarter of all eligible families use child care subsidies, and usage varies widely across states and local areas reflecting various barriers to access and scarcity of quality center-based care. The authors conclude that to achieve welfare reform's ultimate goal of breaking the cycle of intergenerational poverty and dependence on government benefits, welfare-to-work programs should promote learning and development among children in welfare and working poor families by increasing access to high-quality child care in low-income neighborhoods.


Subject(s)
Child Care/organization & administration , Child Welfare/economics , Health Planning/legislation & jurisprudence , Public Assistance/legislation & jurisprudence , Child , Child Welfare/legislation & jurisprudence , Child, Preschool , Humans , Infant , Infant, Newborn , Public Assistance/organization & administration , Quality of Health Care , United States
19.
Eur J Immunol ; 32(3): 895-902, 2002 03.
Article in English | MEDLINE | ID: mdl-11870634

ABSTRACT

CD40 is expressed on a wide array of hematopoietic and non-hematopoietic cells, including keratinocytes. The pivotal in vivo function of CD40 on hematopoietic cells in the regulation of both humoral and cell-mediated immunity is well established. However, whether CD40 expression on non-hematopoietic cells influences immunity has until now not been addressed. Therefore, we transgenically expressed human CD40 (hCD40) under the control of the keratin 14 promoter to drive expression of hCD40 in basal keratinocytes of mice. When we selectively engaged hCD40 in vivo on the keratinocytes of these mice, the keratinocytes secreted TNF-alpha, resulting in dendritic cell migration to draining lymph nodes and enhanced in vitro T cell priming to an epicutaneously applied chemical sensitizer. Exclusive CD40 engagement on keratinocytes during a contact hypersensitivity response displayed exacerbated and prolonged cutaneous immune reactions relative to control mice. Thus, CD40 engagement on non-hematopoietic cells, such as keratinocytes, can amplify cutaneous and regional T cell responses in vivo.


Subject(s)
CD40 Antigens/immunology , Immunity, Cellular , Keratinocytes/immunology , Animals , Antibodies, Monoclonal/immunology , Antibodies, Monoclonal/pharmacology , CD40 Antigens/genetics , Chemotaxis , Dendritic Cells/immunology , Dermatitis, Allergic Contact/immunology , Ear, External , Epidermis/immunology , Female , Humans , Keratins/genetics , Lymph Nodes/immunology , Mice , Mice, Transgenic , Organ Specificity , Oxazolone/immunology , Oxazolone/toxicity , Promoter Regions, Genetic , RNA, Messenger/biosynthesis , Recombinant Fusion Proteins/immunology , T-Lymphocytes/immunology , Tumor Necrosis Factor-alpha/metabolism
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