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2.
Dermatology ; 237(2): 236-247, 2021.
Article in English | MEDLINE | ID: mdl-32101870

ABSTRACT

Podoconiosis is a form of lymphoedema that occurs in tropical highland areas in genetically susceptible individuals who are exposed to irritant volcanic soils. The disease is preventable through consistent use of footwear and attention to foot hygiene; however, in endemic areas there is a strong barefoot tradition, and many cannot afford shoes. Patients with podoconiosis face significant physical disability, psychological comorbidity, reduced quality of life and experience frequent episodes of systemic illness due to acute dermatolymphangioadenitis. This review provides an overview of this important and neglected tropical skin disease and summarizes the latest research findings.


Subject(s)
Clay , Cost of Illness , Elephantiasis/etiology , Africa South of the Sahara/epidemiology , Asia, Southeastern/epidemiology , Central America/epidemiology , Elephantiasis/diagnosis , Elephantiasis/epidemiology , Elephantiasis/therapy , Genetic Predisposition to Disease , Humans , Mental Health , Neglected Diseases , Shoes , Social Stigma , South America/epidemiology
3.
Dermatology ; 235(2): 79-90, 2019.
Article in English | MEDLINE | ID: mdl-30544123

ABSTRACT

Human scabies, a common infestation, has a worldwide distribution with a variable impact and presentation depending on the clinical situation. In developed, high-income settings, health institution and residential home outbreaks challenge health and social care services. In resource-poor settings, it is the downstream sequelae of staphylococcal and streptococcal bacteraemia, induced by scratching, which have a significant impact on the long-term health of communities. Over the past decade scabies has been recognised as a "neglected tropical disease" (NTD) by the World Health Organisation, has an accepted practical system of global diagnostic criteria and is being adopted into integrated programmes of mass drug administration for NTDs in field settings. This review seeks to summarise the recent advances in the understanding of scabies and highlight the advocacy and research headlines with their implication for diagnosis and management of outbreaks and individuals. In addition, it will indicate the priorities and questions that remain.


Subject(s)
Developed Countries , Developing Countries , Ivermectin/therapeutic use , Permethrin/therapeutic use , Scabies/diagnosis , Scabies/drug therapy , Global Burden of Disease , Humans , Insecticides/therapeutic use , Scabies/complications , Scabies/prevention & control , Skin Diseases, Bacterial/parasitology
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