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Bioorg Med Chem
; 20(6): 2002-9, 2012 Mar 15.
Article
in English
| MEDLINE
| ID: mdl-22356736
ABSTRACT
Twenty kinds of cyclic dipeptides containing l-leucine were synthesized, and their antioxidant activity against ·OH and O(2)(·-) was investigated. Compounds possessing polar amino acid residues, such as Asp, Cys, Glu, Lys, Pro, Ser, and Trp, exhibited higher antioxidant activity against ·OH than vitamin E. However, only cyclo(l-Cys-l-Leu) scavenged O(2)(·-).