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1.
An Bras Dermatol ; 97(3): 366-368, 2022.
Article in English | MEDLINE | ID: mdl-35428530

ABSTRACT

The number of skin infections caused by atypical mycobacteria has increased in recent decades. They usually appear after contact with wounds and interruptions in the integrity of the skin. The present report describes a case of cutaneous infection by Mycobacterium marinum, in a young, immunocompetent patient, with a prolonged evolution, diagnosed through a skin lesion culture (from a spindle biopsy of the skin). The patient was treated with multidrug therapy, including clarithromycin, doxycycline, and rifampicin, due to the lesion extent, with satisfactory results. A brief review of the literature is also provided.


Subject(s)
Mycobacterium Infections, Nontuberculous , Mycobacterium marinum , Skin Diseases, Bacterial , Skin Diseases, Infectious , Anti-Bacterial Agents/therapeutic use , Cellulitis , Drug Therapy, Combination , Humans , Leprostatic Agents/therapeutic use , Mycobacterium Infections, Nontuberculous/diagnosis , Mycobacterium Infections, Nontuberculous/drug therapy , Mycobacterium Infections, Nontuberculous/microbiology , Nontuberculous Mycobacteria , Skin Diseases, Bacterial/diagnosis , Skin Diseases, Bacterial/drug therapy , Skin Diseases, Bacterial/microbiology
4.
An. bras. dermatol ; 97(3): 366-368, 2022. graf
Article in English | LILACS-Express | LILACS | ID: biblio-1383567

ABSTRACT

Abstract The number of skin infections caused by atypical mycobacteria has increased in recent decades. They usually appear after contact with wounds and interruptions in the integrity of the skin. The present report describes a case of cutaneous infection by Mycobacterium marinum, in a young, immunocompetent patient, with a prolonged evolution, diagnosed through a skin lesion culture (from a spindle biopsy of the skin). The patient was treated with multidrug therapy, including clarithromycin, doxycycline, and rifampicin, due to the lesion extent, with satisfactory results. A brief review of the literature is also provided.

5.
Orthop J Sports Med ; 9(3): 2325967121990016, 2021 Mar.
Article in English | MEDLINE | ID: mdl-34250161

ABSTRACT

BACKGROUND: The removal of all adherent muscle tissue from the hamstring graft during anterior cruciate ligament reconstruction (ACLR) is common practice. However, there is a paucity of research to justify this removal or evaluate its biological implications. PURPOSE/HYPOTHESIS: The purpose of this study was to (1) evaluate the histological characteristics of the myotendinous muscle tissue harvested from hamstring tendons, (2) compare the final diameter of the prepared graft before and after the removal of the remnant musculature, and (3) evaluate patients who were treated with and without preservation of the graft-adhered muscle. The hypothesis was that the adherent musculature of the graft would have cells that could contribute to graft incorporation and revascularization, assist in the proprioceptive capacity of the neoligament, and increase the graft's diameter. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: We divided 84 patients into 2 groups: group 1 underwent ACLR using hamstring tendon autograft with adherent musculature, and group 2 underwent ACLR using hamstring tendon autograft stripped of its remnant muscle. All patients had minimum 2-year follow-up. The muscle harvested from the graft in group 2 was submitted for histological examination, and the graft diameter before and after muscle removal was compared. The Tegner activity scale and Lysholm scores were determined preoperatively and at 12 and 24 months postoperatively. RESULTS: There was a significant difference in graft diameter between groups. The evaluation of the graft diameter in group 2 showed a decrease of 11.52% after removal of muscle tissue from the tendon graft. Patients from group 1 had better Tegner and Lysholm scores (mean ± SD) after 12 months (Tegner, 8.03 vs 7 [P = .004]; Lysholm, 95.48 ± 1.2 vs 87.54 ± 3.21 [P = .002]) and better Lysholm scores after 24 months (95.76 ± 2.1 vs 89.32 ± 2.47; P = .002). The muscle tissue of the analyzed fragments presented a pattern with fibrous tissue beams, invaginating regularly and sequentially from the myotendinous junction into the muscles. CONCLUSION: Preserving the muscle tissue on tendon grafts promoted a volumetric increase in the final autograft diameter and demonstrated biological and regenerative potential. Patients who underwent ACLR using the tendon with the muscle attached had better functional scores at 2-year follow-up as compared with patients treated using the tendon with the muscle removed.

6.
An Bras Dermatol ; 94(6): 717-720, 2019.
Article in English | MEDLINE | ID: mdl-31789249

ABSTRACT

Confluent and reticulated papillomatosis of Gougerot and Carteaud is a rare dermatosis with onset during puberty, more prevalent in females than in males. The pathogenesis is unknown, but some theories suggest either a keratinization or endocrine disorder. The lesions are verrucous, brownish, hyperkeratotic papules or spots that coalesce in a confluent and/or reticulated pattern. This report presents a case with extensive cutaneous involvement associated with acanthosis nigricans and good response to treatment with methotrexate.


Subject(s)
Dermatologic Agents/therapeutic use , Methotrexate/therapeutic use , Papilloma/drug therapy , Papilloma/pathology , Skin Neoplasms/drug therapy , Skin Neoplasms/pathology , Adolescent , Biopsy , Erythema/pathology , Humans , Male , Treatment Outcome
7.
An. bras. dermatol ; 94(6): 717-720, Nov.-Dec. 2019. graf
Article in English | LILACS | ID: biblio-1054891

ABSTRACT

Abstract Confluent and reticulated papillomatosis of Gougerot and Carteaud is a rare dermatosis with onset during puberty, more prevalent in females than in males. The pathogenesis is unknown, but some theories suggest either a keratinization or endocrine disorder. The lesions are verrucous, brownish, hyperkeratotic papules or spots that coalesce in a confluent and/or reticulated pattern. This report presents a case with extensive cutaneous involvement associated with acanthosis nigricans and good response to treatment with methotrexate.


Subject(s)
Humans , Male , Adolescent , Papilloma/pathology , Papilloma/drug therapy , Skin Neoplasms/pathology , Skin Neoplasms/drug therapy , Methotrexate/therapeutic use , Dermatologic Agents/therapeutic use , Biopsy , Treatment Outcome , Erythema/pathology
8.
An Bras Dermatol ; 92(3): 395-397, 2017.
Article in English | MEDLINE | ID: mdl-29186257

ABSTRACT

Lymphangioma is a rare benign disease of the lymphatic vessels. Typically, they are primary conditions but may be acquired secondarily, such as those caused by irradiation during radiotherapy for the treatment of breast cancer. The local lymphatic obstruction provoked by irradiation causes the appearance of asymptomatic hyaline vesicles on the irradiated skin. The present report describes a 78-year-old female patient, who initially presented hyaline vesicles that progressed into multiple papules with serous exudation of a yellowish and odorless secretion on the area of chronic radiodermitis in right breast. Despite the rarity of the case, we emphasize the importance of knowledge regarding dermatological disease for early diagnosis and proper medical conduct.


Subject(s)
Breast Neoplasms/radiotherapy , Lymphangioma/diagnosis , Neoplasms, Radiation-Induced/diagnosis , Aged , Breast Neoplasms/surgery , Female , Humans , Lymphangioma/etiology , Mastectomy
9.
An. bras. dermatol ; 92(3): 395-397, May-June 2017. graf
Article in English | LILACS | ID: biblio-886978

ABSTRACT

Abstract Lymphangioma is a rare benign disease of the lymphatic vessels. Typically, they are primary conditions but may be acquired secondarily, such as those caused by irradiation during radiotherapy for the treatment of breast cancer. The local lymphatic obstruction provoked by irradiation causes the appearance of asymptomatic hyaline vesicles on the irradiated skin. The present report describes a 78-year-old female patient, who initially presented hyaline vesicles that progressed into multiple papules with serous exudation of a yellowish and odorless secretion on the area of chronic radiodermitis in right breast. Despite the rarity of the case, we emphasize the importance of knowledge regarding dermatological disease for early diagnosis and proper medical conduct.


Subject(s)
Humans , Female , Aged , Breast Neoplasms/radiotherapy , Lymphangioma/diagnosis , Neoplasms, Radiation-Induced/diagnosis , Breast Neoplasms/surgery , Lymphangioma/etiology , Mastectomy
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