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Nat Prod Res ; 35(17): 2831-2839, 2021 Sep.
Article in English | MEDLINE | ID: mdl-31583912

ABSTRACT

An unprecedented saponin is being reported herein together with five known compounds from the methanol extract of the roots of Albizia adianthifolia. The metabolites were obtained over repeated open column chromatography methods and spectroscopic followed by spectrometric techniques. The isolated compounds were tested against eleven Gram-negative bacteria including multidrug resistant strains. The results revealed considerable inhibition of the new saponin against the studied bacteria with MIC values ranging from 16 to 128 µg/mL.


Subject(s)
Albizzia , Anti-Bacterial Agents/pharmacology , Saponins , Albizzia/chemistry , Anti-Bacterial Agents/isolation & purification , Phytochemicals/isolation & purification , Phytochemicals/pharmacology , Plant Extracts/pharmacology , Plant Roots/chemistry , Saponins/isolation & purification , Saponins/pharmacology
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