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1.
Clin Infect Dis ; 52(5): 585-92, 2011 Mar 01.
Article in English | MEDLINE | ID: mdl-21292663

ABSTRACT

BACKGROUND: Foodborne botulism resulting from consumption of uncooked aquatic game foods has been an endemic hazard among Alaska Native populations for centuries. Our review was conducted to help target botulism prevention and response activities. METHODS: Records of Alaska botulism investigations for the period 1947-2007 were reviewed. We used the Centers for Disease Control and Prevention case definitions for foodborne botulism and linear regression to evaluate incidence trends and χ(2) or Fisher's Exact tests to evaluate categorical data. RESULTS: A total of 317 patients (61% of whom were female) and 159 outbreaks were reported. Overall mean annual incidence was 6.9 cases per 100,000 Alaska Native persons; mean incidence was lower in 2000 (5.7 cases per 100,000 Alaska Native persons) than in any period since 1965-1969 (0.8 cases per 100,000 Alaska Native persons). Age-specific incidence was highest (26.6 cases per 100,000 Alaska Native persons) among persons aged ≥60 years. The overall case-fatality rate was 8.2%, and the case-fatality rate was ≤4.0% since 1980. Misdiagnosis was associated with a higher case-fatality rate and delayed antitoxin administration. CONCLUSIONS: Foodborne botulism remains a public health problem in Alaska. Incidence might be decreasing, but it remains >800 times the overall US rate (0.0068 cases per 100,000 persons). Prevention messages should highlight the additional risk to female individuals and older persons. Early diagnosis is critical for timely access to antitoxin and supportive care.


Subject(s)
Endemic Diseases , Adolescent , Adult , Aged , Aged, 80 and over , Alaska , Botulism/epidemiology , Child , Child, Preschool , Female , Humans , Incidence , Male , Middle Aged , Population Groups , Young Adult
2.
J Healthc Inf Manag ; 24(1): 18-24, 2010.
Article in English | MEDLINE | ID: mdl-20077921

ABSTRACT

US healthcare is undergoing a transformation. The economic stimulus plan is intended to transform healthcare through health IT. The government has defined "meaningful use" of health IT. Healthcare is a team activity, and as such presents a challenge to the concept of meaningful use. While encoding clinical data into a computer is a positive step, it is not enough. A continuity-of-care record is needed to document and measure care; support clinical care; and coordinate care with public health agencies. This paper examines current research to assist decisionmakers moving forward. To realize the promise, integration across all clinical disciplines is critical. There are many challenges. These include: the threat of information overload, both at the transitions of care and between disciplines; the need to provide for data-sharing between clinical and public health agencies, an important component in both local community and national health issues; how to use health IT to improve the delivery of healthcare, especially with unintended outcomes of any change in healthcare and paper persistence; and addressing different views of "meaningful" for different uses and users of health IT. All of these challenges need to be considered for wise installation of health IT. In addition, attention must be paid to weaknesses in the current healthcare system to prevent codifying them in health IT.


Subject(s)
American Recovery and Reinvestment Act , Interdisciplinary Communication , Medical Records Systems, Computerized/organization & administration , Medical Records Systems, Computerized/economics , Public Health Informatics , United States
3.
Pediatr Infect Dis J ; 23(9): 875-7, 2004 Sep.
Article in English | MEDLINE | ID: mdl-15361731

ABSTRACT

We document an echovirus 18 meningitis outbreak occurring at a remote overnight children's camp in Alaska. The outbreak involved 26% of 113 camp residents, was associated with building overcrowding and occurred in a camp with a contaminated drinking water source. Lack of specific children's camp regulations and failure to implement and enforce existing regulations may have contributed to the outbreak.


Subject(s)
Communicable Disease Control , Disease Outbreaks , Echovirus Infections/epidemiology , Enterovirus B, Human/classification , Meningitis, Viral/epidemiology , Adolescent , Adult , Age Distribution , Aged , Aged, 80 and over , Alaska/epidemiology , Camping , Child , Child, Preschool , Cohort Studies , Echovirus Infections/diagnosis , Female , Humans , Infant , Logistic Models , Male , Meningitis, Viral/diagnosis , Middle Aged , Multivariate Analysis , Probability , Retrospective Studies , Risk Assessment , Sex Distribution
4.
J Infect Dis ; 189 Suppl 1: S86-90, 2004 May 01.
Article in English | MEDLINE | ID: mdl-15106095

ABSTRACT

A measles outbreak occurred among a highly vaccinated population in Alaska during 1998, providing an opportunity to determine the incremental efficacy of >or=2 doses of measles-containing vaccine (MCV) compared with 1 dose. Of 33 confirmed case patients identified, 31 had been vaccinated with 1 dose of MCV, 1 had received 2 doses, and vaccination status was unknown in 1 case. Seventy percent of cases were school-associated; 58% of cases occurred in 2 high schools. Of 3679 students attending the 2 schools, 50.4% and 45.5% had received >or=2 doses of MCV before measles introduction at the schools. The relative risk of developing measles among persons vaccinated with >or=2 doses of MCV compared with 1 dose was 0.06 (95% confidence interval, 0.01-0.44; P<.001), yielding an estimated incremental vaccine efficacy of 94.1% (95% confidence interval, 55.9%-99.2%; P<.001). Rapid implementation of a mandatory second-dose MCV requirement probably limited the extent of this outbreak.


Subject(s)
Disease Outbreaks/prevention & control , Immunization, Secondary , Measles-Mumps-Rubella Vaccine/administration & dosage , Measles-Mumps-Rubella Vaccine/therapeutic use , Measles/prevention & control , Adolescent , Adult , Alaska/epidemiology , Child, Preschool , Cohort Studies , Female , Humans , Male , Measles/epidemiology , Retrospective Studies , Treatment Outcome , Vaccination , Vaccines, Combined
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