Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 4 de 4
Filter
Add more filters










Database
Publication year range
4.
AIDS ; 3(4): 235-7, 1989 Apr.
Article in English | MEDLINE | ID: mdl-2500957

ABSTRACT

One hundred and ninety-nine patients with a history of intravenous drug abuse, and enrolled on the St Luke's-Roosevelt Hospital Center Methadone Program, had baseline evaluations performed from September 1984 to April 1987. The study was designed to examine immunologic parameters associated with HIV seropositivity and those predictive of progression to AIDS-related complex (ARC) and AIDS. Sixty-four patients (32%) had antibodies to HIV by enzyme-linked immunosorbent assay (ELISA), with confirmation by Western blot and none of these patients had ARC or AIDS at the time of initial evaluation. The mean values for white blood-cell count, absolute lymphocyte count, proportion and absolute CD4, and CD4/CD8 ratio were decreased significantly in the HIV-seropositive group compared with the HIV-seronegative group. On the other hand, levels of circulating beta 2-microglobulin, SCD8, SIL-2R, and HIV p24 antigen were significantly elevated in the HIV-seropositive group compared with the HIV-seronegative group.


Subject(s)
AIDS-Related Complex/immunology , Acquired Immunodeficiency Syndrome/immunology , HIV Antibodies/analysis , Methadone/therapeutic use , Substance-Related Disorders/immunology , AIDS-Related Complex/complications , Acquired Immunodeficiency Syndrome/complications , Adult , Antigens, Differentiation, T-Lymphocyte/analysis , Blotting, Western , Enzyme-Linked Immunosorbent Assay , Female , HIV Antigens/analysis , HIV Core Protein p24 , Humans , Leukocyte Count , Male , New York City , Receptors, Interleukin-2/analysis , Retroviridae Proteins/analysis , Substance-Related Disorders/complications , Substance-Related Disorders/rehabilitation , beta 2-Microglobulin/analysis
SELECTION OF CITATIONS
SEARCH DETAIL
...