Exercise at given percentages of VO2max: heterogeneous metabolic responses between individuals.

PURPOSE: Given percentages of VO(2max) are widely used for training and study purposes although they might not result in homogeneous metabolic strain. Therefore, the homogeneity of metabolic responses to prolonged exercise at fixed percentages of VO(2max) should be investigated. PROCEDURES: Twenty-one healthy male subjects (29+/-5 years, 77+/-8 kg, VO(2max): 59.9+/-11.8 ml min(-1)kg(-1)) performed two incremental tests to exhaustion on a cycle ergometer to determine VO(2max). Subsequently, two 60 min tests at 60 and 75% VO(2max) were conducted in randomised order. VO(2) was kept constant by adjusting the work rate. Blood lactate (La) responses as primary outcome variable to quantify metabolic strain were assessed. FINDINGS: Mean La was 2.1+/-1.1 mmol l(-1) (min-max: 0.7-5.6 mmol l(-1)) during the 60% VO(2max) test and 4.6+/-1.9 mmol l(-1) (min-max: 2.2-8.0 mmol l(-1)) during the 75% VO(2max) test. The coefficients of variation of La amounted for 52.4 and 41.3% during the 60 and 75% VO(2max) test, respectively. La responses did not differ significantly between three subgroups of the subjects (N=7 with VO(2max)<55 ml min(-1)kg(-1), N=7 with VO(2max) 55-65 ml min(-1)kg(-1), and N=7 with VO(2 max)>65 ml min(-1)kg(-1); P>or=0.08). CONCLUSION: Altogether, prolonged exercise at given percentages of VO(2max) leads to inhomogeneous metabolic strain as indicated by the large variability of La responses. This holds true even in subgroups of similar aerobic capacity. Thus, intensity prescription for endurance training and study purposes should not be solely based upon percentages of VO(2max) when a comparable metabolic strain is intended.

Determination of "Fatmax"with 1 h cycling protocols of constant load.

Several earlier studies were aimed at determining an exercise intensity that elicits maximal fat oxidation (Fatmax). However, these studies employed few different intensities or used exercise periods of too short a duration. All investigators described intensity with reference to maximal ergometric values, which might lead to metabolically inhomogeneous workloads between individuals. The aim of this study was to determine Fatmax by overcoming these methodological shortcomings of earlier investigations. Ten healthy recreational athletes (29 +/- 5 y; 75 +/- 6 kg; 1.81 +/- 0.04 m) conducted an initial incremental cycling test to determine VO2 peak (59.2 +/- 6.1 mL.min-1.kg-1) and individual anaerobic threshold (IAT; 221 +/- 476 W). Within 4 weeks, 5 constant-load tests of 1 h duration were carried out at 55%, 65%, 75%, 85%, and 95% IAT. During all tests indirect calorimetry (MetaMax I, Cortex, Leipzig, Germany) served to quantify fat oxidation. Capillary blood sampling for lactate measurements was conducted every 15 min. All subjects remained in a lactate steady state during the constant load tests, which minimized influences from excess CO2. There was no difference between the 5 intensities for the percentage of energy from fat metabolism (p = 0.12). Additionally, the intensities led to similar absolute amounts of oxidized fat (p = 0.34). However, there was a significant increase in fat metabolism with increasing exercise duration (p = 0.04). It is impossible to define one theoretical optimal intensity for fat oxidation that is true in all individuals. It is thus mandatory to perform an individual assessment with indirect calorimetry. Intra-individual day-to-day variation might render the use of several tests of long duration less applicable than incremental testing with stages of sufficient duration.