Review of the treatment of liver hydatid cysts.

UNLABELLED: A review was carried out in Medline, LILACS and the Cochrane Library. Our database search strategy included the following terms: "hydatid cyst", "liver", "management", "meta-analysis" and "randomized controlled trial". No language limits were used in the literature search. The latest electronic search date was the 7(th) of January 2014. INCLUSION AND EXCLUSION CRITERIA: all relevant studies on the assessment of therapeutic methods for hydatid cysts of the liver were considered for analysis. Information from editorials, letters to publishers, low quality review articles and studies done on animals were excluded from analysis. Additionally, well-structured abstracts from relevant articles were selected and accepted for analysis. Standardized forms were designed for data extraction; two investigators entered the data on patient demographics, methodology, recurrence of HC, mean cyst size and number of cysts per group. Four hundred and fourteen articles were identified using the previously described search strategy. After applying the inclusion and exclusion criteria detailed above, 57 articles were selected for final analysis: one meta-analysis, 9 randomized clinical trials, 5 non-randomized comparative prospective studies, 7 non-comparative prospective studies, and 34 retrospective studies (12 comparative and 22 non-comparative). Our results indicate that antihelminthic treatment alone is not the ideal treatment for liver hydatid cysts. More studies in the literature support the effectiveness of radical treatment compared with conservative treatment. Conservative surgery with omentoplasty is effective in preventing postoperative complications. A laparoscopic approach is safe in some situations. Percutaneous drainage with albendazole therapy is a safe and effective alternative treatment for hydatid cysts of the liver. Radical surgery with pre- and post-operative administration of albendazole is the best treatment option for liver hydatid cysts due to low recurrence and complication rates.

Leiomiosarcoma con patrón fusocelular y epitelioide en cuerpo del páncreas. Utilidad de la inmunohistoquímica en el diagnóstico diferencial de las neoplasias mesenquimales pancreáticas / Leiomyosarcoma with spindle and epithelioid pattern in the pancreatic body. The role of immunohistochemistry in the differential diagnosis of mesenchymal pancreatic tumours

Los leiomiosarcomas pancreáticos son neoplasias altamente agresivas con muy mal pronóstico. Se describe un caso de un paciente masculino de 78 años de edad que presenta un tumor abdominal en el que los estudios radiológicos confirmaron el origen primario en el páncreas. El estudio morfológico mostró un sarcoma con morfología fusocelular y epitelioide, con un perfil inmunohistoquímico positivo para actina músculo liso y desmina con negatividad para miogenina, h-caldesmon, CD117, DOG-1, S100, MyoD1, cromogranina-A, HMB-45, Melan A y EBV, confirmando el diagnóstico de leiomiosarcoma fusocelular y epitelioide. Se discute el diagnóstico diferencial con otras neoplasias mesenquimales pancreáticas(AU)

Pancreatic leiomyosarcoma is a highly aggressive malignancy with a poor prognosis. We report a case of a 78-year-old man with an abdominal mass which was diagnosed radiologically as a primary pancreatic sarcoma. Histopathology revealed a spindle/epithelioid cells morphology and immunohistochemistry showed strong positivity for smooth muscle actin and desmin, with negative results for myogenin, h-caldesmon, CD117, DOG-1, S100, MyoD1, chromogranin-A, HMB-45, Melan-A and EBV. The diagnosis of spindle and epithelioid leiomyosarcoma was confirmed. The differential diagnosis with pancreatic mesenchymal lesions is discussed(AU)

Nuevo método de operar en la eventración compleja: separación anatómica de componentes con prótesis y nuevas inserciones musculares / New surgical technique in complex incisional hernias: Component Separation Technique (CST) with prosthesis and new muscle insertions

Introducción El objetivo de este trabajo es mostrar a la comunidad quirúrgica una nueva técnica para el tratamiento de eventraciones complejas y catastróficas desarrollada en este equipo: separación anatómica de componentes (SAC) modificada por Carbonell-Bonafé. Material y método Se trató a 100 pacientes con eventración compleja. Se documentó tamaño, contenido y reductibilidad de la eventración (tomografía computarizada preoperatoria), recidivas y técnicas de cierre previas, talla y peso, alteraciones tróficas de la piel y necesidad de neumoperitoneo preoperatorio. Se operó siguiendo un protocolo homogéneo, con medida de presión intraabdominal antes, durante y tras la intervención. Se evaluó al paciente en consulta a los 15 y 30 días, mensualmente durante 3 meses, al sexto mes y anualmente hasta 5 años. Resultados Entre enero de 2003 y mayo de 2008 se intervino a 100 pacientes consecutivos. En el postoperatorio inmediato se tuvo un 12% de seromas, un 8% de isquemia parcial de bordes de la herida y un fallecimiento debido a fallo multiorgánico; en el postoperatorio tardío se tuvo un 6% de algias transitorias en los puntos de anclaje óseo. Los pacientes reanudaron su actividad habitual en una media de 2 meses con gran mejoría en su calidad de vida. No se han encontrado recidivas hasta la fecha. Conclusiones La técnica SAC que esta Unidad ha modificado es un excelente recurso en el tratamiento de grandes eventraciones: garantiza el éxito del cierre con poca morbilidad y, además, reconstruye la biomecánica de la pared abdominal (AU)

Introduction Our goal is to show the surgical community a new technique developed by our team for treating complex and catastrophic ventral hernias: Separation of Anatomical Component (SAC) amended by Carbonell–Bonafé. Materials and methods A total of 100 patients with complex incisional hernias have been treated. The size, content and reducibility of ventral hernia (preoperative CT scan), recurrences and pre-closure techniques, height and weight, trophic skin alterations and need for preoperative pneumoperitoneum were all documented. The operation was performed following a standardised protocol; intra-abdominal pressure (IAP) was measured before, during and after the intervention. Patients were evaluated in the clinic at 15 and 30 days, monthly for 3 months, at sixth months and annually for up to 5 years. Results A total of 100 consecutive patients were operated on between January 2003 and May 2008. In the immediate post-surgical period there were 12% seromas, 8% of partial-ischaemia on the edges of the wound and 1 death due to multi-organ failure. In the later period, 6% had transitional pain in bone anchorage points. They resumed their normal activities after an average of 2 months, with great improvement in their quality of life. There have been no recurrences to date. Conclusions The SAC technique, as modified by our Unit, is an excellent resource in managing large ventral hernias: successfully closing with low morbidity, as well as reconstructing the biomechanics of the abdominal wall (AU)

[New surgical technique in complex incisional hernias: Component Separation Technique (CST) with prosthesis and new muscle insertions]. / Nuevo método de operar en la eventración compleja: separación anatómica de componentes con prótesis y nuevas inserciones musculares.

INTRODUCTION: Our goal is to show the surgical community a new technique developed by our team for treating complex and catastrophic ventral hernias: Separation of Anatomical Component (SAC) amended by Carbonell-Bonafé. MATERIALS AND METHODS: A total of 100 patients with complex incisional hernias have been treated. The size, content and reducibility of ventral hernia (preoperative CT scan), recurrences and pre-closure techniques, height and weight, trophic skin alterations and need for preoperative pneumoperitoneum were all documented. The operation was performed following a standardised protocol; intra-abdominal pressure (IAP) was measured before, during and after the intervention. Patients were evaluated in the clinic at 15 and 30 days, monthly for 3 months, at sixth months and annually for up to 5 years. RESULTS: A total of 100 consecutive patients were operated on between January 2003 and May 2008. In the immediate post-surgical period there were 12% seromas, 8% of partial-ischaemia on the edges of the wound and 1 death due to multi-organ failure. In the later period, 6% had transitional pain in bone anchorage points. They resumed their normal activities after an average of 2 months, with great improvement in their quality of life. There have been no recurrences to date. CONCLUSIONS: The SAC technique, as modified by our Unit, is an excellent resource in managing large ventral hernias: successfully closing with low morbidity, as well as reconstructing the biomechanics of the abdominal wall.