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1.
Rev Invest Clin ; 52(1): 25-30, 2000.
Article in Spanish | MEDLINE | ID: mdl-10818807

ABSTRACT

OBJECTIVE: Demonstrate the utility of centelleography using 111In-octreotide in carotid glomus simple o multiple in comparison to erythrocytes with 99mTc calculate the sensitivity, specificity and accuracy of both test. DESIGN: Comparative survey (Diagnostic test) Place: Hospital Oncológico de Concentración del Distrito Federal (Mexico). SUBJECTS: Twenty patients sent to nuclear medicine service for carotid glomus diagnosis. MAIN MEASURES: All of the patients went under a centelleography with 111In-octreotide labeled erythrocytes. Diagnostic was confirmed with US and CAT, taking as the gold standard the selective angiography and/or histopathology. RESULTS: Using 99mTc-labeled erythrocytes resulted in; True positives 13, true negatives 3, false positive 3, false negative 1. Sensitivity 92%, specificity 50%, accuracy 80% and Using 111In-octreotide: True positive 14, true negative 6, and 100% sensitivity, specificity was obtained. CONCLUSIONS: We consider that Centelleography with 111In-octreotide must be the selected image methodology to accurately diagnose carotid glomus, previous to surgery, or in case of patients prior to radiotherapy that because of age, damage size or location can not be candidates for surgery.


Subject(s)
Carotid Body Tumor/diagnostic imaging , Erythrocytes , Indium Radioisotopes , Octreotide/analogs & derivatives , Technetium , Adult , Aged , Female , Humans , Male , Middle Aged , Predictive Value of Tests , Prospective Studies , Radionuclide Imaging , Sensitivity and Specificity
2.
Rev Invest Clin ; 43(2): 119-23, 1991.
Article in Spanish | MEDLINE | ID: mdl-1947464

ABSTRACT

This is a retrospective study of 96 cases of carotid body tumor studies over a 20 year period. This tumor appears most often in females, and its frequency increases after the age of forty. In this group of patients, the sea level altitude of the place of residence appeared to be the main associative factor in the origin of the tumors. The symptoms are few, and usually the presence of the tumor is the only sign. The carotid angiography was the main study used to confirm the diagnosis. In thirty two cases surgery was performed: total resection was possible in twenty two cases and partial resection in three. In five cases it was only possible to obtain a biopsy from the tumor. The remaining two were found to be nonresectable. Surgical complications were minimal, except for one immediate postoperative death. No functionality was shown in any of the cases; only two cases were malignant, and one case was shown to be of familial origin. Our conclusion is that surgery should be performed on patients with tumors of five cm or less, under fifty years of age, with low surgical risk, and with a high tumor growth rate. Other patients can be managed with periodic examinations.


Subject(s)
Carotid Body Tumor , Adult , Aged , Aged, 80 and over , Carotid Body Tumor/diagnosis , Carotid Body Tumor/epidemiology , Carotid Body Tumor/therapy , Female , Humans , Male , Middle Aged , Retrospective Studies
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