1.
Pol J Pharmacol Pharm
; 38(3): 309-19, 1986.
Article
in English
| MEDLINE
| ID: mdl-3490658
ABSTRACT
The synthesis of two Schiff bases of aryl methyl ketones and ethylenediamine 1c, 1d, symmetric adducts of aryl isothiocyanates with Schiff bases 2d-2m and 2-thioxopyrrolidine-4,5-dione derivatives 4d-4m obtained by condensation of oxalyl chloride with Schiff bases of aroylthioacetic acid anilides and ethylenediamine is described. Some of 13 investigated compounds 4a, 4b, 4d-4l, 5a, 5b of 2-thioxopyrrolidine-4,5-dione type showed sedative and analgesic action.