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1.
Chimia (Aarau) ; 71(7): 525-527, 2017 Aug 09.
Article in English | MEDLINE | ID: mdl-28779777

ABSTRACT

This article provides an overview of activities in the fields of continuous processes, flow chemistry and microreactors at the Universities of Applied Sciences in Switzerland.

2.
Chimia (Aarau) ; 66(5): 347-9, 2012.
Article in English | MEDLINE | ID: mdl-22867552

ABSTRACT

Thin-layer chromatography (TLC) is a mature and very established technique, frequently used in many fields of applications ranging from natural product analysis to chemical or pharmaceutical applications. The introduction of a commercially available TLC-MS interface was a major step complementing the ease of use of TLC with structural elucidation power of mass spectrometry (MS). The TLC-MS interface simplifies the workflow dramatically to gain structural information directly from TLC separations. This article describes the potential of TLC-nuclear magnetic resonance spectroscopy (NMR) utilizing the TLC-MS interface to straightforwardly characterize zones of interest by NMR spectroscopy with a focus on quantification of active pharmaceutical ingredients (API) in formulations and identification of active principles in plant extracts.


Subject(s)
Biological Products/analysis , Chromatography, Thin Layer/methods , Magnetic Resonance Spectroscopy/methods , Pharmaceutical Preparations/analysis , Chemistry, Pharmaceutical , Mass Spectrometry , Plant Extracts/analysis
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