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Turk Kardiyol Dern Ars ; 46(2): 136-139, 2018 03.
Article in English | MEDLINE | ID: mdl-29512614

ABSTRACT

Heparin-induced thrombocytopenia (HIT) and heparin-induced thrombocytopenia and thrombosis are potentially fatal adverse reactions to heparin therapy caused by the formation of polyclonal antibodies against the platelet factor 4-heparin complex. Fatal limb and organ damage or death may occur as a result of this immunological drug reaction. Described in this case report is the management of a patient who developed HIT after undergoing a MitraClip transcatheter mitral valve repair. The aim was to encourage clinicians to pay special attention to a frail patient who receives heparin therapy and to advise clinicians that clinical scores and laboratory tests should be used as a complement for certain diagnosis. The decision about continuation or cessation of heparin therapy is an important cornerstone for hospitalized patients with HIT.


Subject(s)
Heart Valve Prosthesis Implantation/instrumentation , Heparin , Postoperative Complications , Thrombocytopenia , Factor Xa Inhibitors/therapeutic use , Fibrinolytic Agents/adverse effects , Fibrinolytic Agents/therapeutic use , Fondaparinux , Heparin/adverse effects , Heparin/therapeutic use , Humans , Male , Middle Aged , Mitral Valve Insufficiency/surgery , Polysaccharides/therapeutic use , Postoperative Complications/chemically induced , Postoperative Complications/drug therapy , Thrombocytopenia/drug therapy , Thrombocytopenia/etiology
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