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J Craniofac Surg ; 25(3): 944-5, 2014 May.
Article in English | MEDLINE | ID: mdl-24657977

ABSTRACT

OBJECTIVE: The aim of this study was to investigate whether neutrophil-lymphocyte ratio (NLR) levels are elevated in patients with Bell palsy (BP). Moreover, we aimed to find out whether there is a correlation between NLR levels and the severity and prognosis of BP. MATERIALS AND METHODS: The study group consisted of 25 subjects who presented with BP and 25 control subjects with no evidence of facial nerve pathology. The subjects underwent a general physical examination; an assessment of laboratory blood parameters; and a cranial magnetic resonance imaging, using gadolinium as a contrast medium. RESULTS: The mean (SD) NLR values were 2.16 (0.80) in the patients with BP and 1.36 (0.48) in the control group. The mean NLR values in the patients with BP were significantly higher than in the control group (P = 0.0001). There was a positive correlation between NLR values and grade of facial paralysis (r = 0.661, P = 0.0001). The mean (SD) NLR values in the grades III, IV, V, and VI BP groups were 1.40 (0.54), 1.78 (0.44), 3.00 (0.63), and 2.60 (0.54), respectively. The mean NLR values in the grade V BP group were significantly higher than in the other groups (P = 0.0001). In addition, there was a positive correlation between NLR values and prognosis of facial paralysis (r = 0.239, P = 0.251). CONCLUSIONS: There is no previous study that investigated the association between NLR and BP in the literature. Higher NLR values in patients with BP may be a predictor of worse prognosis.


Subject(s)
Bell Palsy/immunology , Leukocyte Count , Lymphocyte Count , Neutrophils/immunology , Acyclovir/pharmacology , Acyclovir/therapeutic use , Adult , Aged, 80 and over , Anti-Inflammatory Agents/pharmacology , Anti-Inflammatory Agents/therapeutic use , Antiviral Agents/pharmacology , Antiviral Agents/therapeutic use , Bell Palsy/classification , Bell Palsy/diagnosis , Bell Palsy/drug therapy , Drug Therapy, Combination , Facial Nerve/drug effects , Facial Nerve/immunology , Female , Humans , Male , Middle Aged , Prednisolone/pharmacology , Prednisolone/therapeutic use , Prognosis , Statistics as Topic
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