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J Int Med Res ; 40(1): 366-70, 2012.
Article in English | MEDLINE | ID: mdl-22429377

ABSTRACT

OBJECTIVE: This retrospective study examined the correlation between carboxy haemoglobin (COHb) levels and vital signs in patients with carbon monoxide (CO) intoxication. METHODS: Over a 10-year period, patients>16 years of age who presented to the emergency department due to CO intoxication were included. Age, gender, comorbidities, month/year of presentation, presenting symptoms, vital signs, blood pH, COHb level, treatment and outcome were recorded. RESULTS: In total, 476 patients were included. The mean±SD age was 36.22±13.65 years; 96.4% of the patients had a normal Glasgow Coma Scale score, 91.0% had normal blood pressure and 80.0% had a normal heart rate. COHb levels were stratified into three groups: <10% (n=39), 10-20% (n=106) and >20% (n=205); levels could not be obtained in the remaining 126 patients. In patients with COHb levels>20%, 34 (16.6%) had alkalosis and nine (4.4%) had acidosis. Among patients with COHb levels>20%, 140 (68.3%) had normal vital signs. CONCLUSIONS: Vital signs cannot be used as a prognostic marker of CO intoxication and, therefore, patients must be monitored closely.


Subject(s)
Carbon Monoxide Poisoning/diagnosis , Carbon Monoxide Poisoning/physiopathology , Vital Signs/physiology , Adult , Blood Pressure/physiology , Carboxyhemoglobin/metabolism , Emergency Service, Hospital , Female , Heart Rate/physiology , Humans , Hydrogen-Ion Concentration , Male
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